Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 134 | 345 | 2.57 | 66 | 49.25% | 34 | 25.37% | 34 | 25.37% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | New England Revolution | 10 | 7 | 2 | 1 | 17 | 11 | +6 | 23 | WWWW | 5 | 5 | 0 | 0 | 10 | 4 | 5 | 2 | 2 | 1 | 7 | 7 | ||
| 2 | Orlando City | 10 | 6 | 3 | 1 | 18 | 7 | +11 | 21 | WWWL | 5 | 3 | 2 | 0 | 10 | 1 | 5 | 3 | 1 | 1 | 8 | 6 | ||
| 3 | Philadelphia Union | 11 | 5 | 4 | 2 | 15 | 10 | +5 | 19 | XWXW | 6 | 3 | 1 | 2 | 7 | 5 | 5 | 2 | 3 | 0 | 8 | 5 | ||
| 4 | 2 | Nashville | 10 | 3 | 6 | 1 | 13 | 11 | +2 | 15 | XWLX | 7 | 3 | 4 | 0 | 11 | 7 | 3 | 0 | 2 | 1 | 2 | 4 | |
| 5 | 1 | New York City | 9 | 4 | 2 | 3 | 16 | 10 | +6 | 14 | WLWL | 5 | 2 | 1 | 2 | 10 | 6 | 4 | 2 | 1 | 1 | 6 | 4 | |
| 6 | 1 | Columbus Crew | 9 | 4 | 2 | 3 | 9 | 7 | +2 | 14 | LWWW | 4 | 3 | 1 | 0 | 7 | 2 | 5 | 1 | 1 | 3 | 2 | 5 | |
| 7 | D.C. United | 10 | 4 | 1 | 5 | 9 | 11 | -2 | 13 | OWWL | 5 | 3 | 0 | 2 | 4 | 3 | 5 | 1 | 1 | 3 | 5 | 8 | ||
| 8 | 1 | CF Montréal | 10 | 3 | 4 | 3 | 11 | 10 | +1 | 13 | XOWL | 4 | 1 | 2 | 1 | 5 | 4 | 6 | 2 | 2 | 2 | 6 | 6 | |
| 9 | 1 | New York Red Bulls | 9 | 4 | 0 | 5 | 14 | 13 | +1 | 12 | LWWL | 5 | 4 | 0 | 1 | 9 | 3 | 4 | 0 | 0 | 4 | 5 | 10 | |
| 10 | Atlanta United | 9 | 2 | 5 | 2 | 11 | 10 | +1 | 11 | LXXX | 4 | 2 | 2 | 0 | 8 | 5 | 5 | 0 | 3 | 2 | 3 | 5 | ||
| 11 | 1 | FC Cincinnati | 9 | 3 | 1 | 5 | 9 | 17 | -8 | 10 | WWLL | 3 | 0 | 0 | 3 | 2 | 6 | 6 | 3 | 1 | 2 | 7 | 11 | |
| 12 | 1 | Inter Miami | 10 | 2 | 2 | 6 | 9 | 16 | -7 | 8 | LLLL | 5 | 0 | 1 | 4 | 4 | 11 | 5 | 2 | 1 | 2 | 5 | 5 | |
| 13 | Toronto FC | 10 | 1 | 2 | 7 | 12 | 20 | -8 | 5 | LLLL | 4 | 1 | 1 | 2 | 6 | 7 | 6 | 0 | 1 | 5 | 6 | 13 | ||
| 14 | Chicago Fire | 10 | 1 | 2 | 7 | 7 | 17 | -10 | 5 | XLLL | 6 | 1 | 2 | 3 | 6 | 9 | 4 | 0 | 0 | 4 | 1 | 8 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Seattle Sounders | 11 | 7 | 4 | 0 | 20 | 7 | +13 | 25 | XWWO | 7 | 4 | 3 | 0 | 14 | 4 | 4 | 3 | 1 | 0 | 6 | 3 | ||
| 2 | Sporting Kansas City | 12 | 7 | 2 | 3 | 22 | 15 | +7 | 23 | WWLX | 7 | 5 | 2 | 0 | 15 | 7 | 5 | 2 | 0 | 3 | 7 | 8 | ||
| 3 | LA Galaxy | 10 | 7 | 0 | 3 | 17 | 15 | +2 | 21 | WWLW | 5 | 4 | 0 | 1 | 9 | 5 | 5 | 3 | 0 | 2 | 8 | 10 | ||
| 4 | Colorado Rapids | 9 | 5 | 1 | 3 | 15 | 11 | +4 | 16 | LWWL | 4 | 3 | 0 | 1 | 10 | 6 | 5 | 2 | 1 | 2 | 5 | 5 | ||
| 5 | 4 | Minnesota United | 10 | 4 | 2 | 4 | 10 | 12 | -2 | 14 | WWXX | 5 | 3 | 0 | 2 | 5 | 3 | 5 | 1 | 2 | 2 | 5 | 9 | |
| 6 | Houston Dynamo | 11 | 3 | 5 | 3 | 15 | 16 | -1 | 14 | XXXL | 5 | 3 | 2 | 0 | 8 | 5 | 6 | 0 | 3 | 3 | 7 | 11 | ||
| 7 | 2 | Portland Timbers | 10 | 4 | 1 | 5 | 13 | 15 | -2 | 13 | LXWL | 5 | 3 | 0 | 2 | 8 | 5 | 5 | 1 | 1 | 3 | 5 | 10 | |
| 8 | 1 | Real Salt Lake | 9 | 3 | 4 | 2 | 14 | 11 | +3 | 13 | XLWX | 6 | 2 | 3 | 1 | 9 | 6 | 3 | 1 | 1 | 1 | 5 | 5 | |
| 9 | 1 | Los Angeles | 10 | 3 | 3 | 4 | 12 | 12 | +0 | 12 | LWXL | 6 | 3 | 2 | 1 | 9 | 5 | 4 | 0 | 1 | 3 | 3 | 7 | |
| 10 | San Jose Earthquakes | 11 | 3 | 1 | 7 | 12 | 20 | -8 | 10 | LLOL | 6 | 2 | 0 | 4 | 9 | 11 | 5 | 1 | 1 | 3 | 3 | 9 | ||
| 11 | Austin FC | 10 | 2 | 3 | 5 | 6 | 11 | -5 | 9 | LOXO | 1 | 0 | 1 | 0 | 0 | 0 | 9 | 2 | 2 | 5 | 6 | 11 | ||
| 12 | Vancouver Whitecaps | 10 | 2 | 2 | 6 | 10 | 16 | -6 | 8 | XLLL | 4 | 2 | 0 | 2 | 4 | 3 | 6 | 0 | 2 | 4 | 6 | 13 | ||
| 13 | FC Dallas | 9 | 1 | 4 | 4 | 9 | 14 | -5 | 7 | LXLX | 5 | 1 | 4 | 0 | 8 | 5 | 4 | 0 | 0 | 4 | 1 | 9 | ||
| 10 | +2 | Javier HERNÁNDEZ (LA Galaxy) |
| 9 | +1 | Raúl RUIDÍAZ (Seattle Sounders) |
| 7 | +1 | Dániel SALLÓI (Sporting Kansas City) |
| 6 | +1 | NANI (Orlando City) |
| +1 | Alan PULIDO (Sporting Kansas City) | |
| +1 | Maximiliano URRUTI (Houston Dynamo) | |
| 5 | +1 | Gonzalo HIGUAÍN (Inter Miami) |
| Jesús MEDINA (New York City) | ||
| Damir KREILACH (Real Salt Lake) | ||
| 4 | Caden CLARK (New York Red Bulls) | |
| Ola KAMARA (D.C. United) | ||
| Adam BUKSA (New England Revolution) | ||
| +1 | Cory BURKE (Philadelphia Union) | |
| +1 | Cristian DÁJOME (Vancouver Whitecaps) | |
| Rubio RUBIN (Real Salt Lake) | ||
| Valentín CASTELLANOS (New York City) | ||
| Ismaël TAJOURI-SHRADI (New York City) | ||
| Gustavo BOU (New England Revolution) |
| Friday, 25 June 2021 | |||||
| Inter Miami | 1-2 | Orlando City | |||
| 67 | Higuaín | 73 | Mueller | ||
| 81 | Nani | ||||
| Saturday, 26 June 2021 | |||||
| Sporting Kansas City | 2-1 | Los Angeles | |||
| 61 | Pulido | 24 | Kim | ||
| 87 | Sallói | ||||
| Chicago Fire | 3-3 | Philadelphia Union | |||
| 2(og) | Glesnes | 28 | Sullivan | ||
| 56 | Sekulić | 45 | Burke | ||
| 67 | Pineda | 79(og) | Sekulić | ||
| Portland Timbers | 0-1 | Minnesota United | |||
| 2 | Hunou | ||||
| Seattle Sounders | 2-2 | Vancouver Whitecaps | |||
| 40 | Ruidíaz | 49 | Dájome | ||
| 71 | Medranda | 56 | Cavallini | ||
| Real Salt Lake | 1-1 | Houston Dynamo | |||
| 11 | Glad | 52 | Urruti | ||
| Toronto FC | 0-2 | FC Cincinnati | |||
| 4 | Cruz | ||||
| 68 | Acosta | ||||
| San Jose Earthquakes | 1-3 | LA Galaxy | |||
| 82 | Cowell | 11 | Hernández | ||
| 50 | Hernández | ||||
| 70(og) | Jungwirth | ||||
| Nashville | 1-1 | CF Montréal | |||
| 90 | Danladi | 63 | Struna | ||
