Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 56 | 149 | 2.66 | 29 | 51.79% | 14 | 25.00% | 13 | 23.21% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | 1 | Philadelphia Union | 4 | 3 | 1 | 0 | 7 | 2 | +5 | 10 | WWWX | 2 | 1 | 1 | 0 | 3 | 1 | 2 | 2 | 0 | 0 | 4 | 1 | |
| 2 | 1 | Columbus Crew | 4 | 2 | 2 | 0 | 10 | 5 | +5 | 8 | XWXW | 2 | 2 | 0 | 0 | 6 | 1 | 2 | 0 | 2 | 0 | 4 | 4 | |
| 3 | 3 | Chicago Fire | 4 | 2 | 2 | 0 | 5 | 1 | +4 | 8 | WWOO | 2 | 1 | 1 | 0 | 3 | 1 | 2 | 1 | 1 | 0 | 2 | 0 | |
| 4 | 1 | New York Red Bulls | 4 | 2 | 1 | 1 | 8 | 4 | +4 | 7 | XLWW | 2 | 0 | 1 | 1 | 1 | 2 | 2 | 2 | 0 | 0 | 7 | 2 | |
| 5 | 3 | Orlando City | 4 | 2 | 1 | 1 | 4 | 2 | +2 | 7 | WLOW | 2 | 1 | 0 | 1 | 3 | 2 | 2 | 1 | 1 | 0 | 1 | 0 | |
| 6 | 1 | Atlanta United | 4 | 2 | 1 | 1 | 8 | 8 | +0 | 7 | XWLW | 3 | 2 | 1 | 0 | 8 | 5 | 1 | 0 | 0 | 1 | 0 | 3 | |
| 7 | 3 | D.C. United | 4 | 2 | 0 | 2 | 5 | 4 | +1 | 6 | LLWW | 2 | 1 | 0 | 1 | 3 | 2 | 2 | 1 | 0 | 1 | 2 | 2 | |
| 8 | 2 | FC Cincinnati | 4 | 2 | 0 | 2 | 5 | 8 | -3 | 6 | WWLL | 2 | 1 | 0 | 1 | 3 | 2 | 2 | 1 | 0 | 1 | 2 | 6 | |
| 9 | 2 | New York City | 4 | 1 | 1 | 2 | 4 | 4 | +0 | 4 | LWOL | 2 | 1 | 0 | 1 | 4 | 3 | 2 | 0 | 1 | 1 | 0 | 1 | |
| 10 | 1 | New England Revolution | 4 | 1 | 1 | 2 | 6 | 8 | -2 | 4 | LLWX | 2 | 1 | 0 | 1 | 3 | 3 | 2 | 0 | 1 | 1 | 3 | 5 | |
| 11 | Toronto FC | 4 | 1 | 1 | 2 | 5 | 8 | -3 | 4 | WLLX | 2 | 1 | 0 | 1 | 3 | 5 | 2 | 0 | 1 | 1 | 2 | 3 | ||
| 12 | 1 | Charlotte FC | 4 | 1 | 0 | 3 | 4 | 7 | -3 | 3 | WLLL | 2 | 1 | 0 | 1 | 3 | 2 | 2 | 0 | 0 | 2 | 1 | 5 | |
| 13 | 1 | CF Montréal | 4 | 0 | 1 | 3 | 5 | 11 | -6 | 1 | XLLL | 1 | 0 | 0 | 1 | 1 | 2 | 3 | 0 | 1 | 2 | 4 | 9 | |
| 14 | 2 | Inter Miami | 4 | 0 | 1 | 3 | 2 | 10 | -8 | 1 | LLLO | 2 | 0 | 1 | 1 | 0 | 2 | 2 | 0 | 0 | 2 | 2 | 8 | |
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Los Angeles | 4 | 3 | 1 | 0 | 9 | 2 | +7 | 10 | WWXW | 3 | 2 | 1 | 0 | 7 | 2 | 1 | 1 | 0 | 0 | 2 | 0 | ||
| 2 | Real Salt Lake | 4 | 3 | 1 | 0 | 6 | 3 | +3 | 10 | WWWO | 2 | 2 | 0 | 0 | 3 | 1 | 2 | 1 | 1 | 0 | 3 | 2 | ||
| 3 | 4 | Minnesota United | 4 | 2 | 2 | 0 | 4 | 2 | +2 | 8 | WWXX | 2 | 1 | 1 | 0 | 2 | 1 | 2 | 1 | 1 | 0 | 2 | 1 | |
| 4 | 1 | Austin FC | 4 | 2 | 1 | 1 | 11 | 3 | +8 | 7 | XLWW | 3 | 2 | 1 | 0 | 11 | 2 | 1 | 0 | 0 | 1 | 0 | 1 | |
| 5 | 3 | FC Dallas | 4 | 2 | 1 | 1 | 7 | 3 | +4 | 7 | WWLX | 3 | 2 | 1 | 0 | 7 | 2 | 1 | 0 | 0 | 1 | 0 | 1 | |
| 6 | 2 | Colorado Rapids | 4 | 2 | 1 | 1 | 6 | 4 | +2 | 7 | XWWL | 2 | 2 | 0 | 0 | 5 | 0 | 2 | 0 | 1 | 1 | 1 | 4 | |
| 7 | 2 | LA Galaxy | 4 | 2 | 0 | 2 | 4 | 4 | +0 | 6 | LLWW | 2 | 1 | 0 | 1 | 1 | 1 | 2 | 1 | 0 | 1 | 3 | 3 | |
| 8 | 1 | Houston Dynamo | 4 | 1 | 2 | 1 | 3 | 3 | +0 | 5 | XWLO | 3 | 1 | 2 | 0 | 3 | 2 | 1 | 0 | 0 | 1 | 0 | 1 | |
| 9 | 3 | Portland Timbers | 4 | 1 | 2 | 1 | 5 | 7 | -2 | 5 | LWXX | 2 | 1 | 1 | 0 | 3 | 2 | 2 | 0 | 1 | 1 | 2 | 5 | |
| 10 | 1 | Seattle Sounders | 4 | 1 | 1 | 2 | 4 | 5 | -1 | 4 | XWLL | 2 | 1 | 0 | 1 | 3 | 3 | 2 | 0 | 1 | 1 | 1 | 2 | |
| 11 | 1 | Nashville | 4 | 1 | 1 | 2 | 3 | 5 | -2 | 4 | LLXW | 0 | 0 | 0 | 0 | 0 | 0 | 4 | 1 | 1 | 2 | 3 | 5 | |
| 12 | Sporting Kansas City | 4 | 1 | 0 | 3 | 3 | 8 | -5 | 3 | LLWL | 1 | 1 | 0 | 0 | 1 | 0 | 3 | 0 | 0 | 3 | 2 | 8 | ||
| 13 | San Jose Earthquakes | 4 | 0 | 1 | 3 | 4 | 9 | -5 | 1 | LLXL | 2 | 0 | 1 | 1 | 4 | 6 | 2 | 0 | 0 | 2 | 0 | 3 | ||
| 14 | Vancouver Whitecaps | 4 | 0 | 1 | 3 | 2 | 9 | -7 | 1 | LLOL | 1 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 0 | 3 | 2 | 9 | ||
| 4 | Lucas ZELARAYÁN (Columbus Crew) | |
| +1 | Carlos VELA (Los Angeles, 1p) | |
| +2 | Brandon VÁZQUEZ (FC Cincinnati) | |
| 3 | Lewis MORGAN (New York Red Bulls) | |
| +1 | Dániel GAZDAG (Philadelphia Union, 1p) | |
| +3 | Jesús FERREIRA (FC Dallas) | |
| Sebastián DRIUSSI (Austin FC) |
| Saturday, 19 March 2022 | |||||
| FC Dallas | 4-1 | Portland Timbers | |||
| 26 | Ferreira | 61 | Niezgoda | ||
| 30 | Ferreira | ||||
| 36 | Ferreira | ||||
| 77 | Arriola | ||||
| Houston Dynamo | 1-1 | Colorado Rapids | |||
| 90 | Pasher | 42 | Kaye | ||
| LA Galaxy | 0-1 | Orlando City | |||
| 9 | Torres | ||||
| Chicago Fire | 3-1 | Sporting Kansas City | |||
| 30 | Przybyłko | 56 | Espinoza | ||
| 50(p) | Shaqiri | ||||
| 82 | Przybyłko | ||||
| Real Salt Lake | 2-1 | Nashville | |||
| 2 | Wood | 25 | Zimmerman | ||
| 54 | Schmitt | ||||
| Toronto FC | 2-1 | D.C. United | |||
| 24 | Pozuelo | 10 | Canouse | ||
| 53 | Osorio | ||||
| Minnesota United | 1-0 | San Jose Earthquakes | |||
| 32 | Amarilla | ||||
| New York City | 0-2 | Philadelphia Union | |||
| 12 | Bedoya | ||||
| 33 | Gazdag | ||||
| Atlanta United | 3-3 | CF Montréal | |||
| 6 | Martínez | 28 | Mihailovic | ||
| 85 | Almada | 37 | Koné | ||
| 90 | Lennon | 42(p) | Quioto | ||
| FC Cincinnati | 3-1 | Inter Miami | |||
| 18 | Matarrita | 30(p) | Higuaín | ||
| 24 | Vázquez | ||||
| 82 | Vázquez | ||||
| Charlotte FC | 3-1 | New England Revolution | |||
| 6 | Świderski | 54(p) | Carles Gil | ||
| 57 | Świderski | ||||
| 64 | Bender | ||||
| Sunday, 20 March 2022 | |||||
| New York Red Bulls | 1-1 | Columbus Crew | |||
| 84 | Barlow | 90 | Nagbe | ||
| Los Angeles | 3-1 | Vancouver Whitecaps | |||
| 27 | Hollingshead | 12 | Blackmon | ||
| 38 | Vela | ||||
| 70 | Hollingshead | ||||
| Austin FC | 1-1 | Seattle Sounders | |||
| 70 | Fagúndez | 43 | Bruin | ||
