Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 14 | 35 | 2.50 | 7 | 50.00% | 5 | 35.71% | 2 | 14.29% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Columbus Crew | 1 | 1 | 0 | 0 | 4 | 0 | +4 | 3 | W--- | 1 | 1 | 0 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 2 | D.C. United | 1 | 1 | 0 | 0 | 3 | 0 | +3 | 3 | W--- | 1 | 1 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 3 | New York Red Bulls | 1 | 1 | 0 | 0 | 3 | 1 | +2 | 3 | W--- | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 3 | 1 | ||
| 4 | Atlanta United | 1 | 1 | 0 | 0 | 3 | 1 | +2 | 3 | W--- | 1 | 1 | 0 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 5 | Orlando City | 1 | 1 | 0 | 0 | 2 | 0 | +2 | 3 | W--- | 1 | 1 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 6 | New England Revolution | 1 | 0 | 1 | 0 | 2 | 2 | +0 | 1 | X--- | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 2 | 2 | ||
| 7 | Toronto FC | 1 | 0 | 1 | 0 | 1 | 1 | +0 | 1 | X--- | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | ||
| 8 | Philadelphia Union | 1 | 0 | 1 | 0 | 1 | 1 | +0 | 1 | X--- | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 9 | Chicago Fire | 1 | 0 | 1 | 0 | 0 | 0 | +0 | 1 | O--- | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | ||
| 10 | Inter Miami | 1 | 0 | 1 | 0 | 0 | 0 | +0 | 1 | O--- | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 11 | New York City | 1 | 0 | 0 | 1 | 0 | 1 | -1 | 0 | L--- | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 1 | ||
| 12 | CF Montréal | 1 | 0 | 0 | 1 | 0 | 2 | -2 | 0 | L--- | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 2 | ||
| 13 | Charlotte FC | 1 | 0 | 0 | 1 | 0 | 3 | -3 | 0 | L--- | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3 | ||
| 14 | FC Cincinnati | 1 | 0 | 0 | 1 | 0 | 5 | -5 | 0 | L--- | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 5 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Austin FC | 1 | 1 | 0 | 0 | 5 | 0 | +5 | 3 | W--- | 1 | 1 | 0 | 0 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 2 | Los Angeles | 1 | 1 | 0 | 0 | 3 | 0 | +3 | 3 | W--- | 1 | 1 | 0 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 3 | Nashville | 1 | 1 | 0 | 0 | 1 | 0 | +1 | 3 | W--- | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | ||
| 4 | LA Galaxy | 1 | 1 | 0 | 0 | 1 | 0 | +1 | 3 | W--- | 1 | 1 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 5 | Portland Timbers | 1 | 0 | 1 | 0 | 2 | 2 | +0 | 1 | X--- | 1 | 0 | 1 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 6 | Minnesota United | 1 | 0 | 1 | 0 | 1 | 1 | +0 | 1 | X--- | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 1 | 1 | ||
| 7 | FC Dallas | 1 | 0 | 1 | 0 | 1 | 1 | +0 | 1 | X--- | 1 | 0 | 1 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 8 | Real Salt Lake | 1 | 0 | 1 | 0 | 0 | 0 | +0 | 1 | O--- | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | ||
| 9 | Houston Dynamo | 1 | 0 | 1 | 0 | 0 | 0 | +0 | 1 | O--- | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 10 | Seattle Sounders | 1 | 0 | 0 | 1 | 0 | 1 | -1 | 0 | L--- | 1 | 0 | 0 | 1 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 11 | San Jose Earthquakes | 1 | 0 | 0 | 1 | 1 | 3 | -2 | 0 | L--- | 1 | 0 | 0 | 1 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | ||
| 12 | Sporting Kansas City | 1 | 0 | 0 | 1 | 1 | 3 | -2 | 0 | L--- | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 1 | 3 | ||
| 13 | Colorado Rapids | 1 | 0 | 0 | 1 | 0 | 3 | -3 | 0 | L--- | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 3 | ||
| 14 | Vancouver Whitecaps | 1 | 0 | 0 | 1 | 0 | 4 | -4 | 0 | L--- | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | 0 | 4 | ||
| 3 | +3 | Carlos VELA (Los Angeles, 1p) |
| 2 | +2 | Michael ESTRADA (D.C. United, 1p) |
| +2 | Cecilio DOMÍNGUEZ (Austin FC) | |
| 1 | +1 | Alexander RING (Austin FC) |
| +1 | ALEXANDRE PATO (Orlando City) | |
| +1 | Luis DÍAZ (Columbus Crew) | |
| +1 | Dominic DWYER (Atlanta United) | |
| +1 | Miguel BERRY (Columbus Crew) | |
| +1 | Javier HERNÁNDEZ (LA Galaxy) | |
| +1 | Lucas ZELARAYÁN (Columbus Crew) | |
| +1 | Derrick ETIENNE (Columbus Crew) | |
| +1 | Tom BARLOW (New York Red Bulls) | |
| +1 | Patryk KLIMALA (New York Red Bulls) | |
| +1 | Aníbal GODOY (Nashville) | |
| +1 | Ola KAMARA (D.C. United) | |
| +1 | Dániel SALLÓI (Sporting Kansas City) | |
| +1 | Sebastián DRIUSSI (Austin FC) | |
| +1 | Jáder OBRIAN (FC Dallas) | |
| +1 | LUIZ de ARAÚJO Guimarães (Atlanta United) | |
| +1 | Javier LÓPEZ (San Jose Earthquakes) | |
| +1 | Brandon BYE (New England Revolution) | |
| +1 | Omir FERNANDEZ (New York Red Bulls) | |
| +1 | Caleb WILEY (Atlanta United) | |
| +1 | Sebastian LLETGET (New England Revolution) | |
| +1 | Cory BURKE (Philadelphia Union) | |
| +1 | Jonathan OSORIO (Toronto FC) | |
| +1 | Robin LOD (Minnesota United) | |
| +1 | Benji MICHEL (Orlando City) | |
| +1 | Dairon ASPRILLA (Portland Timbers) | |
| +1 | Yimmi CHARÁ (Portland Timbers) |
| Saturday, 26 February 2022 | |||||
| D.C. United | 3-0 | Charlotte FC | |||
| 37(p) | Estrada | ||||
| 45 | Estrada | ||||
| 65 | Kamara | ||||
| FC Dallas | 1-1 | Toronto FC | |||
| 9 | Obrian | 45 | Osorio | ||
| Columbus Crew | 4-0 | Vancouver Whitecaps | |||
| 8 | Berry | ||||
| 25 | Etienne | ||||
| 84 | Díaz | ||||
| 87 | Zelarayán | ||||
| Portland Timbers | 2-2 | New England Revolution | |||
| 60 | Asprilla | 41 | Bye | ||
| 78 | Chará | 63 | Lletget | ||
| San Jose Earthquakes | 1-3 | New York Red Bulls | |||
| 69 | López | 45 | Klimala | ||
| 72 | Fernandez | ||||
| 90 | Barlow | ||||
| Philadelphia Union | 1-1 | Minnesota United | |||
| 35 | Burke | 23 | Lod | ||
| Los Angeles | 3-0 | Colorado Rapids | |||
| 29(p) | Vela | ||||
| 35 | Vela | ||||
| 50 | Vela | ||||
| Austin FC | 5-0 | FC Cincinnati | |||
| 2 | Domínguez | ||||
| 14 | Ring | ||||
| 43 | Driussi | ||||
| 61 | Domínguez | ||||
| 90(og) | Kann | ||||
| Inter Miami | 0-0 | Chicago Fire | |||
| Sunday, 27 February 2022 | |||||
| Houston Dynamo | 0-0 | Real Salt Lake | |||
| LA Galaxy | 1-0 | New York City | |||
| 90 | Hernández | ||||
| Seattle Sounders | 0-1 | Nashville | |||
| 80 | Godoy | ||||
| Orlando City | 2-0 | CF Montréal | |||
| 49 | Alexandre Pato | ||||
| 59 | Michel | ||||
| Atlanta United | 3-1 | Sporting Kansas City | |||
| 20 | Luiz Araújo | 85 | Sallói | ||
| 45 | Dwyer | ||||
| 89 | Wiley | ||||
