Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
| 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 154 | 365 | 2.37 | 75 | 48.70% | 40 | 25.97% | 39 | 25.32% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Columbus Crew | 20 | 11 | 4 | 5 | 28 | 19 | +9 | 37 | LWLW | 10 | 8 | 0 | 2 | 16 | 6 | 10 | 3 | 4 | 3 | 12 | 13 | ||
| 2 | New York Red Bulls | 20 | 9 | 4 | 7 | 21 | 22 | -1 | 31 | LWOX | 10 | 6 | 1 | 3 | 10 | 8 | 10 | 3 | 3 | 4 | 11 | 14 | ||
| 3 | Toronto FC | 19 | 7 | 5 | 7 | 21 | 21 | +0 | 26 | LWLX | 10 | 6 | 4 | 0 | 14 | 5 | 9 | 1 | 1 | 7 | 7 | 16 | ||
| 4 | Chicago Fire | 16 | 5 | 6 | 5 | 21 | 21 | +0 | 21 | OWLL | 8 | 2 | 4 | 2 | 9 | 8 | 8 | 3 | 2 | 3 | 12 | 13 | ||
| 5 | 1 | New England Revolution | 18 | 6 | 3 | 9 | 18 | 27 | -9 | 21 | WWXW | 10 | 5 | 2 | 3 | 13 | 11 | 8 | 1 | 1 | 6 | 5 | 16 | |
| 6 | 1 | Kansas City Wizards | 19 | 5 | 5 | 9 | 15 | 22 | -7 | 20 | LXWX | 10 | 4 | 3 | 3 | 11 | 9 | 9 | 1 | 2 | 6 | 4 | 13 | |
| 7 | Philadelphia Union | 19 | 4 | 5 | 10 | 23 | 34 | -11 | 17 | XXLL | 9 | 3 | 4 | 2 | 14 | 12 | 10 | 1 | 1 | 8 | 9 | 22 | ||
| 8 | D.C. United | 20 | 3 | 3 | 14 | 13 | 35 | -22 | 12 | LLLL | 10 | 2 | 1 | 7 | 7 | 16 | 10 | 1 | 2 | 7 | 6 | 19 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | LA Galaxy | 20 | 13 | 4 | 3 | 32 | 13 | +19 | 43 | WLXW | 9 | 6 | 2 | 1 | 19 | 9 | 11 | 7 | 2 | 2 | 13 | 4 | ||
| 2 | Real Salt Lake | 21 | 11 | 6 | 4 | 36 | 16 | +20 | 39 | WXXW | 11 | 8 | 3 | 0 | 26 | 6 | 10 | 3 | 3 | 4 | 10 | 10 | ||
| 3 | FC Dallas | 19 | 8 | 9 | 2 | 27 | 17 | +10 | 33 | WWXX | 9 | 5 | 3 | 1 | 14 | 7 | 10 | 3 | 6 | 1 | 13 | 10 | ||
| 4 | Seattle Sounders | 21 | 8 | 5 | 8 | 23 | 25 | -2 | 29 | OWWW | 11 | 5 | 2 | 4 | 14 | 12 | 10 | 3 | 3 | 4 | 9 | 13 | ||
| 5 | Colorado Rapids | 19 | 7 | 7 | 5 | 21 | 18 | +3 | 28 | XWXL | 9 | 4 | 4 | 1 | 11 | 7 | 10 | 3 | 3 | 4 | 10 | 11 | ||
| 6 | San Jose Earthquakes | 18 | 7 | 5 | 6 | 21 | 20 | +1 | 26 | WLLX | 9 | 4 | 2 | 3 | 12 | 10 | 9 | 3 | 3 | 3 | 9 | 10 | ||
| 7 | Houston Dynamo | 20 | 5 | 5 | 10 | 23 | 30 | -7 | 20 | LLXL | 10 | 4 | 3 | 3 | 16 | 11 | 10 | 1 | 2 | 7 | 7 | 19 | ||
| 8 | Chivas USA | 19 | 5 | 4 | 10 | 22 | 25 | -3 | 19 | OLWX | 9 | 3 | 2 | 4 | 11 | 11 | 10 | 2 | 2 | 6 | 11 | 14 | ||
| 13 | +1 | Edson BUDDLE (LA Galaxy) |
| 11 | Juan Pablo ÁNGEL (New York Red Bulls, 1p) | |
| 9 | Sébastien LE TOUX (Philadelphia Union, 2p) | |
| 8 | Álvaro SABORIO (Real Salt Lake) | |
| Dwayne DE ROSARIO (Toronto FC, 2p) | ||
| Fredy MONTERO (Seattle Sounders) | ||
| 7 | Kei KAMARA (Kansas City Wizards) | |
| +2 | Danny MWANGA (Philadelphia Union) | |
| +1 | Chris WONDOLOWSKI (San Jose Earthquakes, 1p) | |
| Justin BRAUN (Chivas USA) | ||
| Steve ZAKUANI (Seattle Sounders) | ||
| Marco PAPPA (Chicago Fire) | ||
| +1 | Jeff CUNNINGHAM (FC Dallas, 2p) | |
| Conor CASEY (Colorado Rapids, 3p) | ||
| 6 | Chad BARRETT (Toronto FC) | |
| +1 | David FERREIRA (FC Dallas, 3p) | |
| +2 | Javier MORALES (Real Salt Lake) | |
| 5 | Landon DONOVAN (LA Galaxy, 3p) | |
| Guillermo BARROS SCHELOTTO (Columbus Crew, 2p) | ||
| +1 | Edgar ESPÍNDOLA (Real Salt Lake) | |
| Omar CUMMINGS (Colorado Rapids) | ||
| Robbie FINDLEY (Real Salt Lake, 1p) | ||
| Zack SCHILAWSKI (New England Revolution) |
| Wednesday, 11 August 2010 | |||||
| New York Red Bulls | 1-0 | Toronto FC | |||
| 23 | Lindpere | ||||
| Philadelphia Union | 1-1 | Real Salt Lake | |||
| 8 | Mwanga | 17 | Espíndola | ||
| Saturday, 14 August 2010 | |||||
| D.C. United | 1-3 | FC Dallas | |||
| 80(og) | Benítez | 36 | Ferreira | ||
| 49 | Alexander | ||||
| 90 | Cunningham | ||||
| New York Red Bulls | 0-1 | LA Galaxy | |||
| 10 | Buddle | ||||
| New England Revolution | 1-0 | Houston Dynamo | |||
| 62 | Stolica | ||||
| Real Salt Lake | 2-0 | Columbus Crew | |||
| 11 | Morales | ||||
| 60 | Morales | ||||
| Chivas USA | 0-0 | Seattle Sounders | |||
| San Jose Earthquakes | 1-0 | Kansas City Wizards | |||
| 35 | Wondolowski | ||||
| Philadelphia Union | 1-1 | Colorado Rapids | |||
| 73 | Mwanga | 59 | Larentowicz | ||
