Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
| 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 107 | 268 | 2.50 | 55 | 51.40% | 24 | 22.43% | 28 | 26.17% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Columbus Crew | 13 | 8 | 3 | 2 | 20 | 12 | +8 | 27 | WWLX | 7 | 6 | 0 | 1 | 11 | 5 | 6 | 2 | 3 | 1 | 9 | 7 | ||
| 2 | New York Red Bulls | 13 | 8 | 0 | 5 | 17 | 16 | +1 | 24 | WWWL | 7 | 5 | 0 | 2 | 9 | 7 | 6 | 3 | 0 | 3 | 8 | 9 | ||
| 3 | Toronto FC | 13 | 5 | 4 | 4 | 16 | 15 | +1 | 19 | XOOW | 7 | 4 | 3 | 0 | 10 | 3 | 6 | 1 | 1 | 4 | 6 | 12 | ||
| 4 | Chicago Fire | 13 | 4 | 5 | 4 | 18 | 18 | +0 | 17 | LWXW | 6 | 2 | 3 | 1 | 9 | 7 | 7 | 2 | 2 | 3 | 9 | 11 | ||
| 5 | Kansas City Wizards | 13 | 3 | 3 | 7 | 11 | 17 | -6 | 12 | LLWO | 7 | 3 | 2 | 2 | 9 | 6 | 6 | 0 | 1 | 5 | 2 | 11 | ||
| 6 | 2 | Philadelphia Union | 12 | 3 | 2 | 7 | 15 | 23 | -8 | 11 | XWLL | 3 | 2 | 1 | 0 | 7 | 4 | 9 | 1 | 1 | 7 | 8 | 19 | |
| 7 | 1 | New England Revolution | 14 | 3 | 2 | 9 | 13 | 26 | -13 | 11 | LLLW | 7 | 2 | 2 | 3 | 9 | 11 | 7 | 1 | 0 | 6 | 4 | 15 | |
| 8 | 1 | D.C. United | 14 | 3 | 2 | 9 | 11 | 25 | -14 | 11 | XLWO | 7 | 2 | 1 | 4 | 5 | 10 | 7 | 1 | 1 | 5 | 6 | 15 | |
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | LA Galaxy | 14 | 10 | 3 | 1 | 22 | 4 | +18 | 33 | OLWW | 6 | 5 | 1 | 0 | 12 | 3 | 8 | 5 | 2 | 1 | 10 | 1 | ||
| 2 | Real Salt Lake | 14 | 8 | 3 | 3 | 27 | 11 | +16 | 27 | WOWO | 8 | 6 | 2 | 0 | 20 | 5 | 6 | 2 | 1 | 3 | 7 | 6 | ||
| 3 | 1 | FC Dallas | 13 | 5 | 6 | 2 | 16 | 12 | +4 | 21 | WWWX | 7 | 3 | 3 | 1 | 9 | 6 | 6 | 2 | 3 | 1 | 7 | 6 | |
| 4 | 1 | Colorado Rapids | 12 | 6 | 3 | 3 | 15 | 11 | +4 | 21 | XXWW | 5 | 3 | 1 | 1 | 7 | 4 | 7 | 3 | 2 | 2 | 8 | 7 | |
| 5 | San Jose Earthquakes | 13 | 5 | 4 | 4 | 16 | 15 | +1 | 19 | XOLX | 7 | 3 | 2 | 2 | 11 | 9 | 6 | 2 | 2 | 2 | 5 | 6 | ||
| 6 | Houston Dynamo | 15 | 5 | 3 | 7 | 21 | 22 | -1 | 18 | XXLL | 8 | 4 | 1 | 3 | 14 | 9 | 7 | 1 | 2 | 4 | 7 | 13 | ||
| 7 | Seattle Sounders | 14 | 4 | 3 | 7 | 15 | 20 | -5 | 15 | LLWL | 8 | 3 | 1 | 4 | 9 | 10 | 6 | 1 | 2 | 3 | 6 | 10 | ||
| 8 | Chivas USA | 14 | 3 | 2 | 9 | 15 | 21 | -6 | 11 | XLLL | 7 | 2 | 1 | 4 | 8 | 10 | 7 | 1 | 1 | 5 | 7 | 11 | ||
| 9 | Edson BUDDLE (LA Galaxy) | |
| 8 | Dwayne DE ROSARIO (Toronto FC, 2p) | |
| Juan Pablo ÁNGEL (New York Red Bulls, 1p) | ||
| 7 | +2 | Álvaro SABORIO (Real Salt Lake) |
| 6 | Kei KAMARA (Kansas City Wizards) | |
| Chris WONDOLOWSKI (San Jose Earthquakes, 1p) | ||
| +1 | Marco PAPPA (Chicago Fire) | |
| +1 | Sébastien LE TOUX (Philadelphia Union, 1p) | |
| Conor CASEY (Colorado Rapids, 3p) | ||
| 5 | +2 | Danny MWANGA (Philadelphia Union) |
| Guillermo BARROS SCHELOTTO (Columbus Crew, 2p) | ||
| Fredy MONTERO (Seattle Sounders) | ||
| Zack SCHILAWSKI (New England Revolution) | ||
| 4 | +1 | Edgar ESPÍNDOLA (Real Salt Lake) |
| Chad BARRETT (Toronto FC) | ||
| Brian McBRIDE (Chicago Fire, 1p) | ||
| Justin BRAUN (Chivas USA) | ||
| Steve ZAKUANI (Seattle Sounders) | ||
| Javier MORALES (Real Salt Lake) | ||
| Jeff CUNNINGHAM (FC Dallas, 2p) |
| Sunday, 27 June 2010 | |||||
| New England Revolution | 0-1 | Chicago Fire | |||
| 30 | Pappa | ||||
| Philadelphia Union | 3-1 | Seattle Sounders | |||
| 54(p) | Le Toux | 44 | Noonan | ||
| 79 | Fred | ||||
| 84 | Mwanga | ||||
| Thursday, 1 July 2010 | |||||
| Toronto FC | 1-1 | Houston Dynamo | |||
| 84 | Gargan | 72 | Ching | ||
| Friday, 2 July 2010 | |||||
| Real Salt Lake | 5-0 | New England Revolution | |||
| 27 | Espíndola | ||||
| 45 | Olave | ||||
| 52 | Saborio | ||||
| 57 | Saborio | ||||
| 85 | Findley | ||||
| Saturday, 3 July 2010 | |||||
| FC Dallas | 1-0 | Kansas City Wizards | |||
| 58(p) | Ferreira | ||||
| Columbus Crew | 2-1 | Chicago Fire | |||
| 43 | Moffat | 44(og) | Hejduk | ||
| 45 | Garey | ||||
| Chivas USA | 1-1 | Philadelphia Union | |||
| 42 | Gavin | 21 | Mwanga | ||
| San Jose Earthquakes | 1-1 | D.C. United | |||
| 16 | Opara | 54 | Najar | ||
