Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
| 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 145 | 351 | 2.42 | 71 | 48.97% | 37 | 25.52% | 37 | 25.52% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Columbus Crew | 19 | 11 | 4 | 4 | 28 | 17 | +11 | 37 | WLWW | 10 | 8 | 0 | 2 | 16 | 6 | 9 | 3 | 4 | 2 | 12 | 11 | ||
| 2 | New York Red Bulls | 18 | 8 | 4 | 6 | 20 | 21 | -1 | 28 | OXLO | 8 | 5 | 1 | 2 | 9 | 7 | 10 | 3 | 3 | 4 | 11 | 14 | ||
| 3 | Toronto FC | 18 | 7 | 5 | 6 | 21 | 20 | +1 | 26 | WLXL | 10 | 6 | 4 | 0 | 14 | 5 | 8 | 1 | 1 | 6 | 7 | 15 | ||
| 4 | Chicago Fire | 16 | 5 | 6 | 5 | 21 | 21 | +0 | 21 | OWLL | 8 | 2 | 4 | 2 | 9 | 8 | 8 | 3 | 2 | 3 | 12 | 13 | ||
| 5 | Kansas City Wizards | 18 | 5 | 5 | 8 | 15 | 21 | -6 | 20 | XWXW | 10 | 4 | 3 | 3 | 11 | 9 | 8 | 1 | 2 | 5 | 4 | 12 | ||
| 6 | 1 | New England Revolution | 17 | 5 | 3 | 9 | 17 | 27 | -10 | 18 | WXWL | 9 | 4 | 2 | 3 | 12 | 11 | 8 | 1 | 1 | 6 | 5 | 16 | |
| 7 | 1 | Philadelphia Union | 17 | 4 | 3 | 10 | 21 | 32 | -11 | 15 | LLXW | 7 | 3 | 2 | 2 | 12 | 10 | 10 | 1 | 1 | 8 | 9 | 22 | |
| 8 | D.C. United | 19 | 3 | 3 | 13 | 12 | 32 | -20 | 12 | LLLL | 9 | 2 | 1 | 6 | 6 | 13 | 10 | 1 | 2 | 7 | 6 | 19 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | LA Galaxy | 19 | 12 | 4 | 3 | 31 | 13 | +18 | 40 | LXWL | 9 | 6 | 2 | 1 | 19 | 9 | 10 | 6 | 2 | 2 | 12 | 4 | ||
| 2 | Real Salt Lake | 19 | 10 | 5 | 4 | 33 | 15 | +18 | 35 | XWXL | 10 | 7 | 3 | 0 | 24 | 6 | 9 | 3 | 2 | 4 | 9 | 9 | ||
| 3 | FC Dallas | 18 | 7 | 9 | 2 | 24 | 16 | +8 | 30 | WXXW | 9 | 5 | 3 | 1 | 14 | 7 | 9 | 2 | 6 | 1 | 10 | 9 | ||
| 4 | Seattle Sounders | 20 | 8 | 4 | 8 | 23 | 25 | -2 | 28 | WWWW | 11 | 5 | 2 | 4 | 14 | 12 | 9 | 3 | 2 | 4 | 9 | 13 | ||
| 5 | Colorado Rapids | 18 | 7 | 6 | 5 | 20 | 17 | +3 | 27 | WXLX | 9 | 4 | 4 | 1 | 11 | 7 | 9 | 3 | 2 | 4 | 9 | 10 | ||
| 6 | San Jose Earthquakes | 17 | 6 | 5 | 6 | 20 | 20 | +0 | 23 | LLXW | 8 | 3 | 2 | 3 | 11 | 10 | 9 | 3 | 3 | 3 | 9 | 10 | ||
| 7 | Houston Dynamo | 19 | 5 | 5 | 9 | 23 | 29 | -6 | 20 | LXLO | 10 | 4 | 3 | 3 | 16 | 11 | 9 | 1 | 2 | 6 | 7 | 18 | ||
| 8 | Chivas USA | 18 | 5 | 3 | 10 | 22 | 25 | -3 | 18 | LWXW | 8 | 3 | 1 | 4 | 11 | 11 | 10 | 2 | 2 | 6 | 11 | 14 | ||
| 12 | Edson BUDDLE (LA Galaxy) | |
| 11 | Juan Pablo ÁNGEL (New York Red Bulls, 1p) | |
| 9 | +1 | Sébastien LE TOUX (Philadelphia Union, 2p) |
| 8 | Álvaro SABORIO (Real Salt Lake) | |
| Dwayne DE ROSARIO (Toronto FC, 2p) | ||
| +1 | Fredy MONTERO (Seattle Sounders) | |
| 7 | +1 | Kei KAMARA (Kansas City Wizards) |
| Justin BRAUN (Chivas USA) | ||
| Steve ZAKUANI (Seattle Sounders) | ||
| Marco PAPPA (Chicago Fire) | ||
| Conor CASEY (Colorado Rapids, 3p) | ||
| 6 | Chris WONDOLOWSKI (San Jose Earthquakes, 1p) | |
| +1 | Chad BARRETT (Toronto FC) | |
| +2 | Jeff CUNNINGHAM (FC Dallas, 2p) | |
| 5 | Landon DONOVAN (LA Galaxy, 3p) | |
| Danny MWANGA (Philadelphia Union) | ||
| Guillermo BARROS SCHELOTTO (Columbus Crew, 2p) | ||
| Omar CUMMINGS (Colorado Rapids) | ||
| +1 | David FERREIRA (FC Dallas, 3p) | |
| +1 | Robbie FINDLEY (Real Salt Lake, 1p) | |
| Zack SCHILAWSKI (New England Revolution) |
| Thursday, 5 August 2010 | |||||
| Philadelphia Union | 1-2 | Columbus Crew | |||
| 45(p) | Le Toux | 43 | Lenhart | ||
| 50 | Lenhart | ||||
| Saturday, 7 August 2010 | |||||
| Colorado Rapids | 1-0 | San Jose Earthquakes | |||
| 26(og) | Busch | ||||
| New England Revolution | 1-0 | D.C. United | |||
| 42 | Phelan | ||||
| Kansas City Wizards | 1-1 | Real Salt Lake | |||
| 21 | Kamara | 33 | Findley | ||
| Toronto FC | 2-1 | Chivas USA | |||
| 21 | Attakora-Gyan | 65(p) | Maldonado | ||
| 32 | Barrett | ||||
| Sunday, 8 August 2010 | |||||
| FC Dallas | 3-1 | Philadelphia Union | |||
| 24(p) | Ferreira | 9 | Moreno | ||
| 75 | Cunningham | ||||
| 81 | Cunningham | ||||
| Chicago Fire | 0-0 | New York Red Bulls | |||
| Seattle Sounders | 2-0 | Houston Dynamo | |||
| 64 | Montero | ||||
| 88 | Fernández | ||||
