Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
| 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 137 | 335 | 2.44 | 66 | 48.18% | 35 | 25.55% | 36 | 26.28% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Columbus Crew | 18 | 10 | 4 | 4 | 26 | 16 | +10 | 34 | LWWL | 10 | 8 | 0 | 2 | 16 | 6 | 8 | 2 | 4 | 2 | 10 | 10 | ||
| 2 | New York Red Bulls | 17 | 8 | 3 | 6 | 20 | 21 | -1 | 27 | XLOX | 8 | 5 | 1 | 2 | 9 | 7 | 9 | 3 | 2 | 4 | 11 | 14 | ||
| 3 | Toronto FC | 17 | 6 | 5 | 6 | 19 | 19 | +0 | 23 | LXLW | 9 | 5 | 4 | 0 | 12 | 4 | 8 | 1 | 1 | 6 | 7 | 15 | ||
| 4 | Chicago Fire | 15 | 5 | 5 | 5 | 21 | 21 | +0 | 20 | WLLW | 7 | 2 | 3 | 2 | 9 | 8 | 8 | 3 | 2 | 3 | 12 | 13 | ||
| 5 | Kansas City Wizards | 17 | 5 | 4 | 8 | 14 | 20 | -6 | 19 | WXWL | 9 | 4 | 2 | 3 | 10 | 8 | 8 | 1 | 2 | 5 | 4 | 12 | ||
| 6 | Philadelphia Union | 15 | 4 | 3 | 8 | 19 | 27 | -8 | 15 | XWLX | 6 | 3 | 2 | 1 | 11 | 8 | 9 | 1 | 1 | 7 | 8 | 19 | ||
| 7 | New England Revolution | 16 | 4 | 3 | 9 | 16 | 27 | -11 | 15 | XWLL | 8 | 3 | 2 | 3 | 11 | 11 | 8 | 1 | 1 | 6 | 5 | 16 | ||
| 8 | D.C. United | 18 | 3 | 3 | 12 | 12 | 31 | -19 | 12 | LLLO | 9 | 2 | 1 | 6 | 6 | 13 | 9 | 1 | 2 | 6 | 6 | 18 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | LA Galaxy | 19 | 12 | 4 | 3 | 31 | 13 | +18 | 40 | LXWL | 9 | 6 | 2 | 1 | 19 | 9 | 10 | 6 | 2 | 2 | 12 | 4 | ||
| 2 | Real Salt Lake | 18 | 10 | 4 | 4 | 32 | 14 | +18 | 34 | WXLW | 10 | 7 | 3 | 0 | 24 | 6 | 8 | 3 | 1 | 4 | 8 | 8 | ||
| 3 | FC Dallas | 17 | 6 | 9 | 2 | 21 | 15 | +6 | 27 | XXWX | 8 | 4 | 3 | 1 | 11 | 6 | 9 | 2 | 6 | 1 | 10 | 9 | ||
| 4 | 2 | Seattle Sounders | 19 | 7 | 4 | 8 | 21 | 25 | -4 | 25 | WWWX | 10 | 4 | 2 | 4 | 12 | 12 | 9 | 3 | 2 | 4 | 9 | 13 | |
| 5 | Colorado Rapids | 17 | 6 | 6 | 5 | 19 | 17 | +2 | 24 | XLXL | 8 | 3 | 4 | 1 | 10 | 7 | 9 | 3 | 2 | 4 | 9 | 10 | ||
| 6 | 2 | San Jose Earthquakes | 16 | 6 | 5 | 5 | 20 | 19 | +1 | 23 | LXWX | 8 | 3 | 2 | 3 | 11 | 10 | 8 | 3 | 3 | 2 | 9 | 9 | |
| 7 | Houston Dynamo | 18 | 5 | 5 | 8 | 23 | 27 | -4 | 20 | XLOX | 10 | 4 | 3 | 3 | 16 | 11 | 8 | 1 | 2 | 5 | 7 | 16 | ||
| 8 | Chivas USA | 17 | 5 | 3 | 9 | 21 | 23 | -2 | 18 | WXWX | 8 | 3 | 1 | 4 | 11 | 11 | 9 | 2 | 2 | 5 | 10 | 12 | ||
| 12 | Edson BUDDLE (LA Galaxy) | |
| 11 | +2 | Juan Pablo ÁNGEL (New York Red Bulls, 1p) |
| 8 | +1 | Álvaro SABORIO (Real Salt Lake) |
| Dwayne DE ROSARIO (Toronto FC, 2p) | ||
| +1 | Sébastien LE TOUX (Philadelphia Union, 1p) | |
| 7 | +1 | Fredy MONTERO (Seattle Sounders) |
| +1 | Justin BRAUN (Chivas USA) | |
| Steve ZAKUANI (Seattle Sounders) | ||
| +1 | Marco PAPPA (Chicago Fire) | |
| Conor CASEY (Colorado Rapids, 3p) | ||
| 6 | Kei KAMARA (Kansas City Wizards) | |
| Chris WONDOLOWSKI (San Jose Earthquakes, 1p) | ||
| 5 | +2 | Landon DONOVAN (LA Galaxy, 3p) |
| Danny MWANGA (Philadelphia Union) | ||
| Guillermo BARROS SCHELOTTO (Columbus Crew, 2p) | ||
| Chad BARRETT (Toronto FC) | ||
| Omar CUMMINGS (Colorado Rapids) | ||
| Zack SCHILAWSKI (New England Revolution) | ||
| 4 | +1 | Brad DAVIS (Houston Dynamo, 2p) |
| Brek SHEA (FC Dallas) | ||
| +1 | Marko PEROVIĆ (New England Revolution) | |
| Edgar ESPÍNDOLA (Real Salt Lake) | ||
| Brian McBRIDE (Chicago Fire, 1p) | ||
| David FERREIRA (FC Dallas, 2p) | ||
| Jesus PADILLA (Chivas USA) | ||
| +1 | Robbie FINDLEY (Real Salt Lake, 1p) | |
| Javier MORALES (Real Salt Lake) | ||
| Emilio RENTERÍA (Columbus Crew) | ||
| Jeff CUNNINGHAM (FC Dallas, 2p) |
| Saturday, 31 July 2010 | |||||
| Houston Dynamo | 2-2 | New York Red Bulls | |||
| 24 | Davis | 10 | Ángel | ||
| 89 | Mullan | 58 | Ángel | ||
| Colorado Rapids | 1-1 | FC Dallas | |||
| 26(p) | Ballouchy | 22(og) | Baudet | ||
| Kansas City Wizards | 1-0 | Toronto FC | |||
| 62 | Bunbury | ||||
| Real Salt Lake | 3-0 | D.C. United | |||
| 13 | Saborio | ||||
| 79 | Findley | ||||
| 90 | González | ||||
| Chivas USA | 3-1 | Columbus Crew | |||
| 37 | Braun | 88 | Lenhart | ||
| 45 | Gavin | ||||
| 53 | Borja | ||||
| San Jose Earthquakes | 0-1 | Seattle Sounders | |||
| 26 | Montero | ||||
| Philadelphia Union | 1-1 | New England Revolution | |||
| 25 | Le Toux | 70 | Perović | ||
| Sunday, 1 August 2010 | |||||
| LA Galaxy | 2-3 | Chicago Fire | |||
| 37(p) | Donovan | 4 | Pappa | ||
| 81(p) | Donovan | 5 | John | ||
| 19 | Banner | ||||
