Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
| 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 116 | 283 | 2.43 | 58 | 50.00% | 27 | 23.28% | 31 | 26.72% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Columbus Crew | 14 | 8 | 4 | 2 | 20 | 12 | +8 | 28 | OWWL | 7 | 6 | 0 | 1 | 11 | 5 | 7 | 2 | 4 | 1 | 9 | 7 | ||
| 2 | New York Red Bulls | 15 | 8 | 2 | 5 | 18 | 17 | +1 | 26 | OXWW | 8 | 5 | 1 | 2 | 9 | 7 | 7 | 3 | 1 | 3 | 9 | 10 | ||
| 3 | Toronto FC | 14 | 6 | 4 | 4 | 17 | 15 | +2 | 22 | WXOO | 8 | 5 | 3 | 0 | 11 | 3 | 6 | 1 | 1 | 4 | 6 | 12 | ||
| 4 | Chicago Fire | 14 | 4 | 5 | 5 | 18 | 19 | -1 | 17 | LLWX | 7 | 2 | 3 | 2 | 9 | 8 | 7 | 2 | 2 | 3 | 9 | 11 | ||
| 5 | 2 | New England Revolution | 15 | 4 | 2 | 9 | 15 | 26 | -11 | 14 | WLLL | 8 | 3 | 2 | 3 | 11 | 11 | 7 | 1 | 0 | 6 | 4 | 15 | |
| 6 | 1 | Kansas City Wizards | 14 | 3 | 3 | 8 | 11 | 19 | -8 | 12 | LLLW | 8 | 3 | 2 | 3 | 9 | 8 | 6 | 0 | 1 | 5 | 2 | 11 | |
| 7 | 1 | D.C. United | 15 | 3 | 3 | 9 | 11 | 25 | -14 | 12 | OXLW | 7 | 2 | 1 | 4 | 5 | 10 | 8 | 1 | 2 | 5 | 6 | 15 | |
| 8 | 2 | Philadelphia Union | 13 | 3 | 2 | 8 | 16 | 25 | -9 | 11 | LXWL | 4 | 2 | 1 | 1 | 8 | 6 | 9 | 1 | 1 | 7 | 8 | 19 | |
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | LA Galaxy | 16 | 11 | 3 | 2 | 25 | 7 | +18 | 36 | LWOL | 7 | 6 | 1 | 0 | 15 | 4 | 9 | 5 | 2 | 2 | 10 | 3 | ||
| 2 | Real Salt Lake | 15 | 9 | 3 | 3 | 28 | 11 | +17 | 30 | WWOW | 8 | 6 | 2 | 0 | 20 | 5 | 7 | 3 | 1 | 3 | 8 | 6 | ||
| 3 | 1 | Colorado Rapids | 14 | 6 | 4 | 4 | 16 | 13 | +3 | 22 | LXXX | 6 | 3 | 2 | 1 | 8 | 5 | 8 | 3 | 2 | 3 | 8 | 8 | |
| 4 | 1 | San Jose Earthquakes | 14 | 6 | 4 | 4 | 18 | 16 | +2 | 22 | WXOL | 7 | 3 | 2 | 2 | 11 | 9 | 7 | 3 | 2 | 2 | 7 | 7 | |
| 5 | 2 | FC Dallas | 13 | 5 | 6 | 2 | 16 | 12 | +4 | 21 | WWWX | 7 | 3 | 3 | 1 | 9 | 6 | 6 | 2 | 3 | 1 | 7 | 6 | |
| 6 | Houston Dynamo | 16 | 5 | 4 | 7 | 21 | 22 | -1 | 19 | OXXL | 9 | 4 | 2 | 3 | 14 | 9 | 7 | 1 | 2 | 4 | 7 | 13 | ||
| 7 | Seattle Sounders | 15 | 4 | 3 | 8 | 16 | 23 | -7 | 15 | LLLW | 8 | 3 | 1 | 4 | 9 | 10 | 7 | 1 | 2 | 4 | 7 | 13 | ||
| 8 | Chivas USA | 15 | 4 | 2 | 9 | 17 | 21 | -4 | 14 | WXLL | 7 | 2 | 1 | 4 | 8 | 10 | 8 | 2 | 1 | 5 | 9 | 11 | ||
| 10 | +1 | Edson BUDDLE (LA Galaxy) |
| 9 | +1 | Juan Pablo ÁNGEL (New York Red Bulls, 1p) |
| 8 | Dwayne DE ROSARIO (Toronto FC, 2p) | |
| 7 | Álvaro SABORIO (Real Salt Lake) | |
| 6 | Kei KAMARA (Kansas City Wizards) | |
| Chris WONDOLOWSKI (San Jose Earthquakes, 1p) | ||
| +2 | Justin BRAUN (Chivas USA) | |
| Marco PAPPA (Chicago Fire) | ||
| Sébastien LE TOUX (Philadelphia Union, 1p) | ||
| Conor CASEY (Colorado Rapids, 3p) | ||
| 5 | Danny MWANGA (Philadelphia Union) | |
| Guillermo BARROS SCHELOTTO (Columbus Crew, 2p) | ||
| Fredy MONTERO (Seattle Sounders) | ||
| +1 | Steve ZAKUANI (Seattle Sounders) | |
| Zack SCHILAWSKI (New England Revolution) | ||
| 4 | Edgar ESPÍNDOLA (Real Salt Lake) | |
| Chad BARRETT (Toronto FC) | ||
| Brian McBRIDE (Chicago Fire, 1p) | ||
| +1 | Omar CUMMINGS (Colorado Rapids) | |
| Javier MORALES (Real Salt Lake) | ||
| Jeff CUNNINGHAM (FC Dallas, 2p) |
| Sunday, 4 July 2010 | |||||
| Colorado Rapids | 1-1 | New York Red Bulls | |||
| 15 | Cummings | 34 | Ángel | ||
| LA Galaxy | 3-1 | Seattle Sounders | |||
| 19 | Buddle | 66 | Zakuani | ||
| 48 | Juninho | ||||
| 77(og) | Riley | ||||
| Thursday, 8 July 2010 | |||||
| Chicago Fire | 0-1 | Real Salt Lake | |||
| 40(p) | Findley | ||||
| Saturday, 10 July 2010 | |||||
| Houston Dynamo | 0-0 | Columbus Crew | |||
| New York Red Bulls | 0-0 | D.C. United | |||
| New England Revolution | 2-0 | LA Galaxy | |||
| 67 | Perović | ||||
| 74 | Dube | ||||
| Kansas City Wizards | 0-2 | Chivas USA | |||
| 56 | Braun | ||||
| 87 | Braun | ||||
| Toronto FC | 1-0 | Colorado Rapids | |||
| 61 | Ibrahim | ||||
| Philadelphia Union | 1-2 | San Jose Earthquakes | |||
| 14 | McInerney | 45 | Glen | ||
| 90 | Álvarez | ||||
