Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
| 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 89 | 224 | 2.51 | 48 | 53.93% | 17 | 19.10% | 24 | 26.97% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Columbus Crew | 11 | 6 | 3 | 2 | 16 | 11 | +5 | 21 | LXLW | 5 | 4 | 0 | 1 | 7 | 4 | 6 | 2 | 3 | 1 | 9 | 7 | ||
| 2 | 1 | New York Red Bulls | 12 | 7 | 0 | 5 | 14 | 16 | -2 | 21 | WWLL | 7 | 5 | 0 | 2 | 9 | 7 | 5 | 2 | 0 | 3 | 5 | 9 | |
| 3 | 1 | Toronto FC | 11 | 5 | 2 | 4 | 15 | 14 | +1 | 17 | OWWO | 5 | 4 | 1 | 0 | 9 | 2 | 6 | 1 | 1 | 4 | 6 | 12 | |
| 4 | 1 | Chicago Fire | 10 | 3 | 4 | 3 | 14 | 14 | +0 | 13 | WXXL | 5 | 2 | 2 | 1 | 7 | 5 | 5 | 1 | 2 | 2 | 7 | 9 | |
| 5 | 1 | New England Revolution | 12 | 3 | 2 | 7 | 13 | 20 | -7 | 11 | LWLO | 6 | 2 | 2 | 2 | 9 | 10 | 6 | 1 | 0 | 5 | 4 | 10 | |
| 6 | Kansas City Wizards | 10 | 2 | 3 | 5 | 9 | 13 | -4 | 9 | OLLX | 5 | 2 | 2 | 1 | 7 | 3 | 5 | 0 | 1 | 4 | 2 | 10 | ||
| 7 | Philadelphia Union | 9 | 2 | 1 | 6 | 11 | 19 | -8 | 7 | LWXL | 2 | 1 | 1 | 0 | 4 | 3 | 7 | 1 | 0 | 6 | 7 | 16 | ||
| 8 | D.C. United | 11 | 2 | 1 | 8 | 7 | 20 | -13 | 7 | OWLL | 7 | 2 | 1 | 4 | 5 | 10 | 4 | 0 | 0 | 4 | 2 | 10 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | LA Galaxy | 12 | 10 | 2 | 0 | 22 | 3 | +19 | 32 | WWWO | 6 | 5 | 1 | 0 | 12 | 3 | 6 | 5 | 1 | 0 | 10 | 0 | ||
| 2 | Real Salt Lake | 11 | 6 | 2 | 3 | 21 | 11 | +10 | 20 | OWWW | 5 | 4 | 1 | 0 | 14 | 5 | 6 | 2 | 1 | 3 | 7 | 6 | ||
| 3 | 2 | Colorado Rapids | 10 | 6 | 1 | 3 | 11 | 7 | +4 | 19 | WWWL | 5 | 3 | 1 | 1 | 7 | 4 | 5 | 3 | 0 | 2 | 4 | 3 | |
| 4 | San Jose Earthquakes | 11 | 5 | 2 | 4 | 15 | 14 | +1 | 17 | LXLW | 6 | 3 | 1 | 2 | 10 | 8 | 5 | 2 | 1 | 2 | 5 | 6 | ||
| 5 | 2 | Houston Dynamo | 13 | 5 | 1 | 7 | 18 | 19 | -1 | 16 | LLLW | 7 | 4 | 0 | 3 | 12 | 7 | 6 | 1 | 1 | 4 | 6 | 12 | |
| 6 | FC Dallas | 11 | 3 | 6 | 2 | 13 | 11 | +2 | 15 | WXLX | 6 | 2 | 3 | 1 | 8 | 6 | 5 | 1 | 3 | 1 | 5 | 5 | ||
| 7 | Seattle Sounders | 12 | 4 | 3 | 5 | 12 | 14 | -2 | 15 | WLLW | 7 | 3 | 1 | 3 | 7 | 7 | 5 | 1 | 2 | 2 | 5 | 7 | ||
| 8 | Chivas USA | 12 | 3 | 1 | 8 | 13 | 18 | -5 | 10 | LLLL | 5 | 2 | 0 | 3 | 6 | 7 | 7 | 1 | 1 | 5 | 7 | 11 | ||
| 9 | Edson BUDDLE (LA Galaxy) | |
| 8 | Dwayne DE ROSARIO (Toronto FC, 2p) | |
| 6 | +1 | Chris WONDOLOWSKI (San Jose Earthquakes, 1p) |
| +1 | Juan Pablo ÁNGEL (New York Red Bulls, 1p) | |
| 5 | Kei KAMARA (Kansas City Wizards) | |
| Álvaro SABORIO (Real Salt Lake) | ||
| Sébastien LE TOUX (Philadelphia Union) | ||
| Zack SCHILAWSKI (New England Revolution) | ||
| 4 | Guillermo BARROS SCHELOTTO (Columbus Crew, 2p) | |
| Chad BARRETT (Toronto FC) | ||
| Brian McBRIDE (Chicago Fire, 1p) | ||
| +1 | Fredy MONTERO (Seattle Sounders) | |
| Justin BRAUN (Chivas USA) | ||
| +1 | Steve ZAKUANI (Seattle Sounders) | |
| Jeff CUNNINGHAM (FC Dallas, 2p) | ||
| Conor CASEY (Colorado Rapids, 3p) | ||
| 3 | +1 | Danny MWANGA (Philadelphia Union) |
| Brad DAVIS (Houston Dynamo, 2p) | ||
| +2 | Brek SHEA (FC Dallas) | |
| +1 | Baggio HUSIDIĆ (Chicago Fire) | |
| +1 | Eddie GAVEN (Columbus Crew) | |
| +2 | Jovan KIROVSKI (LA Galaxy) | |
| Edgar ESPÍNDOLA (Real Salt Lake) | ||
| Jesus PADILLA (Chivas USA) | ||
| Javier MORALES (Real Salt Lake) | ||
| +1 | Marco PAPPA (Chicago Fire) |
| Wednesday, 2 June 2010 | |||||
| New York Red Bulls | 2-1 | Houston Dynamo | |||
| 15 | Ubiparipović | 65 | Ching | ||
| 90 | Ángel | ||||
| San Jose Earthquakes | 2-2 | Columbus Crew | |||
| 6 | Álvarez | 5 | Gaven | ||
| 79 | Wondolowski | 70 | Marshall | ||
| Saturday, 5 June 2010 | |||||
| D.C. United | 0-0 | Real Salt Lake | |||
| FC Dallas | 2-0 | San Jose Earthquakes | |||
| 58 | Shea | ||||
| 60 | Shea | ||||
| Colorado Rapids | 1-0 | Columbus Crew | |||
| 85 | Moor | ||||
| New York Red Bulls | 1-0 | Chivas USA | |||
| 27 | Stammler | ||||
| LA Galaxy | 4-1 | Houston Dynamo | |||
| 1 | Kirovski | 7 | Weaver | ||
| 21 | Kirovski | ||||
| 48 | Bowen | ||||
| 56 | Alex Cazumba | ||||
| Chicago Fire | 2-1 | Philadelphia Union | |||
| 14 | Husidić | 90 | Mwanga | ||
| 74 | Pappa | ||||
| Seattle Sounders | 3-0 | New England Revolution | |||
| 5 | Gonzalez | ||||
| 24 | Zakuani | ||||
| 42 | Montero | ||||
| Toronto FC | 0-0 | Kansas City Wizards | |||
