Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
| 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 123 | 296 | 2.40 | 61 | 49.59% | 29 | 23.58% | 33 | 26.83% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Columbus Crew | 16 | 9 | 4 | 3 | 22 | 13 | +9 | 31 | WLOW | 9 | 7 | 0 | 2 | 13 | 6 | 7 | 2 | 4 | 1 | 9 | 7 | ||
| 2 | New York Red Bulls | 16 | 8 | 2 | 6 | 18 | 19 | -1 | 26 | LOXW | 8 | 5 | 1 | 2 | 9 | 7 | 8 | 3 | 1 | 4 | 9 | 12 | ||
| 3 | Toronto FC | 15 | 6 | 4 | 5 | 18 | 17 | +1 | 22 | LWXO | 8 | 5 | 3 | 0 | 11 | 3 | 7 | 1 | 1 | 5 | 7 | 14 | ||
| 4 | Chicago Fire | 14 | 4 | 5 | 5 | 18 | 19 | -1 | 17 | LLWX | 7 | 2 | 3 | 2 | 9 | 8 | 7 | 2 | 2 | 3 | 9 | 11 | ||
| 5 | 1 | Kansas City Wizards | 16 | 4 | 4 | 8 | 13 | 20 | -7 | 16 | XWLL | 8 | 3 | 2 | 3 | 9 | 8 | 8 | 1 | 2 | 5 | 4 | 12 | |
| 6 | 2 | Philadelphia Union | 14 | 4 | 2 | 8 | 18 | 26 | -8 | 14 | WLXW | 5 | 3 | 1 | 1 | 10 | 7 | 9 | 1 | 1 | 7 | 8 | 19 | |
| 7 | 2 | New England Revolution | 15 | 4 | 2 | 9 | 15 | 26 | -11 | 14 | WLLL | 8 | 3 | 2 | 3 | 11 | 11 | 7 | 1 | 0 | 6 | 4 | 15 | |
| 8 | 1 | D.C. United | 16 | 3 | 3 | 10 | 11 | 26 | -15 | 12 | LOXL | 8 | 2 | 1 | 5 | 5 | 11 | 8 | 1 | 2 | 5 | 6 | 15 | |
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | LA Galaxy | 16 | 11 | 3 | 2 | 25 | 7 | +18 | 36 | LWOL | 7 | 6 | 1 | 0 | 15 | 4 | 9 | 5 | 2 | 2 | 10 | 3 | ||
| 2 | Real Salt Lake | 16 | 9 | 3 | 4 | 28 | 13 | +15 | 30 | LWWO | 8 | 6 | 2 | 0 | 20 | 5 | 8 | 3 | 1 | 4 | 8 | 8 | ||
| 3 | 2 | FC Dallas | 15 | 6 | 7 | 2 | 19 | 13 | +6 | 25 | WXWW | 8 | 4 | 3 | 1 | 11 | 6 | 7 | 2 | 4 | 1 | 8 | 7 | |
| 4 | 1 | Colorado Rapids | 15 | 6 | 5 | 4 | 17 | 14 | +3 | 23 | XLXX | 7 | 3 | 3 | 1 | 9 | 6 | 8 | 3 | 2 | 3 | 8 | 8 | |
| 5 | 1 | San Jose Earthquakes | 14 | 6 | 4 | 4 | 18 | 16 | +2 | 22 | WXOL | 7 | 3 | 2 | 2 | 11 | 9 | 7 | 3 | 2 | 2 | 7 | 7 | |
| 6 | Houston Dynamo | 16 | 5 | 4 | 7 | 21 | 22 | -1 | 19 | OXXL | 9 | 4 | 2 | 3 | 14 | 9 | 7 | 1 | 2 | 4 | 7 | 13 | ||
| 7 | Seattle Sounders | 17 | 5 | 4 | 8 | 18 | 24 | -6 | 19 | WXLL | 9 | 3 | 2 | 4 | 10 | 11 | 8 | 2 | 2 | 4 | 8 | 13 | ||
| 8 | Chivas USA | 15 | 4 | 2 | 9 | 17 | 21 | -4 | 14 | WXLL | 7 | 2 | 1 | 4 | 8 | 10 | 8 | 2 | 1 | 5 | 9 | 11 | ||
| 10 | Edson BUDDLE (LA Galaxy) | |
| 9 | Juan Pablo ÁNGEL (New York Red Bulls, 1p) | |
| 8 | Dwayne DE ROSARIO (Toronto FC, 2p) | |
| 7 | Álvaro SABORIO (Real Salt Lake) | |
| +1 | Sébastien LE TOUX (Philadelphia Union, 1p) | |
| +1 | Conor CASEY (Colorado Rapids, 3p) | |
| 6 | Kei KAMARA (Kansas City Wizards) | |
| Chris WONDOLOWSKI (San Jose Earthquakes, 1p) | ||
| +1 | Fredy MONTERO (Seattle Sounders) | |
| Justin BRAUN (Chivas USA) | ||
| Marco PAPPA (Chicago Fire) | ||
| 5 | Danny MWANGA (Philadelphia Union) | |
| Guillermo BARROS SCHELOTTO (Columbus Crew, 2p) | ||
| +1 | Chad BARRETT (Toronto FC) | |
| Steve ZAKUANI (Seattle Sounders) | ||
| Zack SCHILAWSKI (New England Revolution) | ||
| 4 | +1 | Brek SHEA (FC Dallas) |
| Edgar ESPÍNDOLA (Real Salt Lake) | ||
| Brian McBRIDE (Chicago Fire, 1p) | ||
| Omar CUMMINGS (Colorado Rapids) | ||
| +1 | David FERREIRA (FC Dallas, 2p) | |
| Javier MORALES (Real Salt Lake) | ||
| Jeff CUNNINGHAM (FC Dallas, 2p) |
| Sunday, 11 July 2010 | |||||
| Seattle Sounders | 1-1 | FC Dallas | |||
| 14 | Montero | 87 | Ferreira | ||
| Wednesday, 14 July 2010 | |||||
| Columbus Crew | 0-1 | Kansas City Wizards | |||
| 14 | Bunbury | ||||
| Thursday, 15 July 2010 | |||||
| D.C. United | 0-1 | Seattle Sounders | |||
| 89 | Levesque | ||||
| Saturday, 17 July 2010 | |||||
| FC Dallas | 2-0 | Real Salt Lake | |||
| 69 | Shea | ||||
| 77 | Harris | ||||
| Colorado Rapids | 1-1 | Kansas City Wizards | |||
| 74 | Casey | 20 | Arnaud | ||
| Columbus Crew | 2-0 | New York Red Bulls | |||
| 20 | Rentería | ||||
| 48 | Carroll | ||||
| Philadelphia Union | 2-1 | Toronto FC | |||
| 61 | Orozco | 81 | Barrett | ||
| 90 | Le Toux | ||||
