| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 188 | 509 | 2.70 | 97 | 51.60% | 59 | 31.38% | 32 | 17.02% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Philadelphia Union | 19 | 8 | 5 | 6 | 32 | 26 | +6 | 29 | WLLW | 10 | 7 | 2 | 1 | 23 | 12 | 9 | 1 | 3 | 5 | 9 | 14 | ||
| 2 | 1 | New York Red Bulls | 20 | 8 | 3 | 9 | 30 | 25 | +5 | 27 | WOLX | 10 | 7 | 1 | 2 | 19 | 9 | 10 | 1 | 2 | 7 | 11 | 16 | |
| 3 | 1 | Montréal Impact | 18 | 6 | 8 | 4 | 29 | 26 | +3 | 26 | XXWX | 8 | 4 | 3 | 1 | 16 | 11 | 10 | 2 | 5 | 3 | 13 | 15 | |
| 4 | Toronto FC | 18 | 6 | 6 | 6 | 20 | 20 | +0 | 24 | XWXL | 7 | 3 | 3 | 1 | 8 | 6 | 11 | 3 | 3 | 5 | 12 | 14 | ||
| 5 | New England Revolution | 19 | 5 | 7 | 7 | 26 | 33 | -7 | 22 | WLLL | 10 | 4 | 4 | 2 | 14 | 11 | 9 | 1 | 3 | 5 | 12 | 22 | ||
| 6 | D.C. United | 18 | 5 | 6 | 7 | 17 | 20 | -3 | 21 | LXWO | 9 | 4 | 1 | 4 | 12 | 9 | 9 | 1 | 5 | 3 | 5 | 11 | ||
| 7 | Orlando City | 18 | 4 | 9 | 5 | 28 | 31 | -3 | 21 | LOLW | 10 | 3 | 7 | 0 | 19 | 14 | 8 | 1 | 2 | 5 | 9 | 17 | ||
| 8 | 1 | Chicago Fire | 17 | 4 | 5 | 8 | 16 | 21 | -5 | 17 | WLWL | 9 | 4 | 3 | 2 | 10 | 8 | 8 | 0 | 2 | 6 | 6 | 13 | |
| 9 | 1 | Columbus Crew | 18 | 3 | 8 | 7 | 23 | 29 | -6 | 17 | XLLX | 9 | 3 | 5 | 1 | 16 | 14 | 9 | 0 | 3 | 6 | 7 | 15 | |
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | FC Dallas | 21 | 11 | 4 | 6 | 31 | 29 | +2 | 37 | LWWW | 10 | 7 | 3 | 0 | 20 | 6 | 11 | 4 | 1 | 6 | 11 | 23 | ||
| 2 | Colorado Rapids | 18 | 9 | 7 | 2 | 21 | 13 | +8 | 34 | XOOW | 9 | 7 | 2 | 0 | 12 | 4 | 9 | 2 | 5 | 2 | 9 | 9 | ||
| 3 | Real Salt Lake | 19 | 8 | 5 | 6 | 29 | 30 | -1 | 29 | LXXL | 8 | 5 | 3 | 0 | 12 | 7 | 11 | 3 | 2 | 6 | 17 | 23 | ||
| 4 | LA Galaxy | 18 | 7 | 8 | 3 | 31 | 18 | +13 | 29 | WWXO | 9 | 5 | 4 | 0 | 20 | 8 | 9 | 2 | 4 | 3 | 11 | 10 | ||
| 5 | Sporting Kansas City | 21 | 8 | 4 | 9 | 24 | 24 | +0 | 28 | LWWX | 11 | 6 | 1 | 4 | 17 | 14 | 10 | 2 | 3 | 5 | 7 | 10 | ||
| 6 | Vancouver Whitecaps | 20 | 8 | 4 | 8 | 31 | 33 | -2 | 28 | WXLW | 11 | 5 | 4 | 2 | 17 | 11 | 9 | 3 | 0 | 6 | 14 | 22 | ||
| 7 | Portland Timbers | 20 | 6 | 8 | 6 | 29 | 30 | -1 | 26 | XOOW | 10 | 6 | 2 | 2 | 20 | 15 | 10 | 0 | 6 | 4 | 9 | 15 | ||
| 8 | San Jose Earthquakes | 18 | 5 | 7 | 6 | 19 | 21 | -2 | 22 | LLXX | 9 | 5 | 3 | 1 | 11 | 5 | 9 | 0 | 4 | 5 | 8 | 16 | ||
| 9 | 1 | Seattle Sounders | 18 | 6 | 2 | 10 | 19 | 21 | -2 | 20 | WLXL | 10 | 5 | 0 | 5 | 12 | 8 | 8 | 1 | 2 | 5 | 7 | 13 | |
| 10 | 1 | Houston Dynamo | 18 | 4 | 6 | 8 | 23 | 25 | -2 | 18 | OWLO | 8 | 4 | 3 | 1 | 14 | 8 | 10 | 0 | 3 | 7 | 9 | 17 | |
| 12 | David VILLA (New York City, 3p) | |
| 11 | +1 | Ignacio PIATTI (Montréal Impact, 2p) |
| 9 | Fanendo ADI (Portland Timbers, 1p) | |
| Bradley WRIGHT-PHILLIPS (New York Red Bulls) | ||
| 8 | Kei KAMARA (New England Revolution, 1p) | |
| Dominic DWYER (Sporting Kansas City) | ||
| Ola KAMARA (Columbus Crew) | ||
| Cyle LARIN (Orlando City) | ||
| Sebastian GIOVINCO (Toronto FC, 2p) | ||
| 7 | Chris WONDOLOWSKI (San Jose Earthquakes, 2p) | |
| +1 | Jordan MORRIS (Seattle Sounders) | |
| Yura MOVSISYAN (Real Salt Lake, 2p) | ||
| Diego VALERI (Portland Timbers, 3p) | ||
| GIOVANI dos Santos (LA Galaxy) | ||
| 6 | Chris PONTIUS (Philadelphia Union) | |
| Robbie KEANE (LA Galaxy, 2p) | ||
| Mike GRELLA (New York Red Bulls) | ||
| Roland ALBERG (Philadelphia Union, 3p) | ||
| Kevin MOLINO (Orlando City, 1p) | ||
| Michael BARRIOS (FC Dallas) | ||
| Pedro MORALES (Vancouver Whitecaps, 5p) | ||
| Juan MARTÍNEZ (Real Salt Lake) |
| Sunday, 10 July 2016 | |||||
| New York Red Bulls | 0-0 | Portland Timbers | |||
| Sporting Kansas City | 3-1 | New York City | |||
| 8 | Feilhaber | 14 | Lampard | ||
| 16 | Medranda | ||||
| 51 | Opara | ||||
| Wednesday, 13 July 2016 | |||||
| New York Red Bulls | 2-0 | Orlando City | |||
| 37 | Lade | ||||
| 59 | Felipe | ||||
| Columbus Crew | 1-1 | Toronto FC | |||
| 54 | Afful | 64 | Hamilton | ||
| Chicago Fire | 1-0 | Sporting Kansas City | |||
| 19 | De Leeuw | ||||
| Vancouver Whitecaps | 2-0 | Real Salt Lake | |||
| 34(og) | Glad | ||||
| 37 | Techera | ||||
| Portland Timbers | 1-1 | Montréal Impact | |||
| 14 | McInerney | 44 | Piatti | ||
| Seattle Sounders | 5-0 | FC Dallas | |||
| 6(p) | Dempsey | ||||
| 18 | Ivanschitz | ||||
| 22 | Morris | ||||
| 61 | Jones | ||||
| 73 | Roldan | ||||