Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 110 | 305 | 2.77 | 60 | 54.55% | 31 | 28.18% | 19 | 17.27% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Montréal Impact | 11 | 4 | 4 | 3 | 18 | 16 | +2 | 16 | XXXX | 5 | 2 | 2 | 1 | 8 | 5 | 6 | 2 | 2 | 2 | 10 | 11 | ||
| 2 | Philadelphia Union | 10 | 4 | 3 | 3 | 14 | 11 | +3 | 15 | XXXW | 5 | 3 | 2 | 0 | 10 | 4 | 5 | 1 | 1 | 3 | 4 | 7 | ||
| 3 | Toronto FC | 10 | 4 | 2 | 4 | 13 | 11 | +2 | 14 | LWLW | 2 | 1 | 0 | 1 | 4 | 4 | 8 | 3 | 2 | 3 | 9 | 7 | ||
| 4 | 2 | D.C. United | 11 | 3 | 4 | 4 | 13 | 13 | +0 | 13 | WLXW | 7 | 3 | 1 | 3 | 10 | 7 | 4 | 0 | 3 | 1 | 3 | 6 | |
| 5 | 2 | New England Revolution | 12 | 2 | 7 | 3 | 15 | 20 | -5 | 13 | WLXX | 6 | 2 | 4 | 0 | 7 | 4 | 6 | 0 | 3 | 3 | 8 | 16 | |
| 6 | 2 | Orlando City | 10 | 2 | 5 | 3 | 17 | 16 | +1 | 11 | LXXL | 5 | 1 | 4 | 0 | 10 | 7 | 5 | 1 | 1 | 3 | 7 | 9 | |
| 7 | 2 | New York Red Bulls | 11 | 3 | 1 | 7 | 13 | 20 | -7 | 10 | LXWW | 5 | 3 | 0 | 2 | 11 | 9 | 6 | 0 | 1 | 5 | 2 | 11 | |
| 8 | Columbus Crew | 10 | 2 | 4 | 4 | 12 | 15 | -3 | 10 | XXLW | 5 | 2 | 2 | 1 | 10 | 9 | 5 | 0 | 2 | 3 | 2 | 6 | ||
| 9 | Chicago Fire | 9 | 1 | 4 | 4 | 8 | 12 | -4 | 7 | LLXL | 5 | 1 | 2 | 2 | 6 | 7 | 4 | 0 | 2 | 2 | 2 | 5 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Colorado Rapids | 12 | 7 | 3 | 2 | 15 | 9 | +6 | 24 | XWWX | 6 | 6 | 0 | 0 | 9 | 2 | 6 | 1 | 3 | 2 | 6 | 7 | ||
| 2 | FC Dallas | 13 | 7 | 2 | 4 | 19 | 19 | +0 | 23 | WWLL | 7 | 5 | 2 | 0 | 13 | 5 | 6 | 2 | 0 | 4 | 6 | 14 | ||
| 3 | 3 | Vancouver Whitecaps | 13 | 6 | 2 | 5 | 20 | 20 | +0 | 20 | WWWL | 7 | 4 | 2 | 1 | 11 | 6 | 6 | 2 | 0 | 4 | 9 | 14 | |
| 4 | 1 | LA Galaxy | 10 | 5 | 4 | 1 | 24 | 12 | +12 | 19 | XWXW | 5 | 4 | 1 | 0 | 17 | 7 | 5 | 1 | 3 | 1 | 7 | 5 | |
| 5 | 1 | San Jose Earthquakes | 11 | 5 | 3 | 3 | 15 | 14 | +1 | 18 | WLXW | 6 | 5 | 1 | 0 | 10 | 3 | 5 | 0 | 2 | 3 | 5 | 11 | |
| 6 | 1 | Real Salt Lake | 10 | 5 | 2 | 3 | 14 | 14 | +0 | 17 | LLWL | 4 | 4 | 0 | 0 | 6 | 2 | 6 | 1 | 2 | 3 | 8 | 12 | |
| 7 | Sporting Kansas City | 13 | 5 | 2 | 6 | 13 | 14 | -1 | 17 | WLLX | 6 | 3 | 1 | 2 | 8 | 7 | 7 | 2 | 1 | 4 | 5 | 7 | ||
| 8 | Seattle Sounders | 10 | 4 | 1 | 5 | 10 | 12 | -2 | 13 | LWWL | 6 | 4 | 0 | 2 | 7 | 4 | 4 | 0 | 1 | 3 | 3 | 8 | ||
| 9 | Portland Timbers | 12 | 3 | 3 | 6 | 17 | 22 | -5 | 12 | LLLW | 6 | 3 | 1 | 2 | 11 | 10 | 6 | 0 | 2 | 4 | 6 | 12 | ||
| 10 | Houston Dynamo | 11 | 3 | 2 | 6 | 18 | 19 | -1 | 11 | WLWL | 6 | 3 | 2 | 1 | 13 | 8 | 5 | 0 | 0 | 5 | 5 | 11 | ||
| 8 | +1 | Fanendo ADI (Portland Timbers, 1p) |
| +1 | David VILLA (New York City, 2p) | |
| +2 | Sebastian GIOVINCO (Toronto FC, 2p) | |
| 7 | Chris WONDOLOWSKI (San Jose Earthquakes, 2p) | |
| 6 | Ignacio PIATTI (Montréal Impact) | |
| 5 | Kei KAMARA (New England Revolution, 1p) | |
| +1 | Dominic DWYER (Sporting Kansas City) | |
| +1 | Michael BARRIOS (FC Dallas) | |
| +1 | C.J. SAPONG (Philadelphia Union) | |
| GIOVANI dos Santos (LA Galaxy) | ||
| +1 | Pedro MORALES (Vancouver Whitecaps, 4p) | |
| 4 | Kennedy IGBOANANIKE (Chicago Fire) | |
| Chris PONTIUS (Philadelphia Union) | ||
| +1 | Álvaro SABORIO (D.C. United) | |
| Robbie KEANE (LA Galaxy, 2p) | ||
| +1 | Cristian BOLAÑOS (Vancouver Whitecaps) | |
| Cyle LARIN (Orlando City) | ||
| Jordan MORRIS (Seattle Sounders) | ||
| Kevin MOLINO (Orlando City, 1p) | ||
| +1 | Giles BARNES (Houston Dynamo) | |
| Gyasi ZARDES (LA Galaxy) | ||
| Mike MAGEE (LA Galaxy) | ||
| Dominic ODURO (Montréal Impact) | ||
| +1 | Didier DROGBA (Montréal Impact, 1p) | |
| Joao PLATA (Real Salt Lake, 1p) |
| Friday, 13 May 2016 | |||||
| D.C. United | 2-0 | New York Red Bulls | |||
| 20 | Saborio | ||||
| 43 | Nyarko | ||||
| Saturday, 14 May 2016 | |||||
| FC Dallas | 2-0 | Seattle Sounders | |||
| 3(p) | Díaz | ||||
| 80 | Barrios | ||||
| Columbus Crew | 1-1 | Colorado Rapids | |||
| 23 | Cedrick | 55 | Doyle | ||
| New England Revolution | 2-0 | Chicago Fire | |||
| 22 | Nguyen | ||||
| 84 | Hollinger-Janzen | ||||
| Montréal Impact | 1-1 | Philadelphia Union | |||
| 3 | Drogba | 24 | Sapong | ||
| Toronto FC | 3-4 | Vancouver Whitecaps | |||
| 37 | Giovinco | 12 | Manneh | ||
| 66 | Giovinco | 18 | Bolaños | ||
| 80 | Moor | 70 | Manneh | ||
| 72 | Morales | ||||
| Sunday, 15 May 2016 | |||||
| Houston Dynamo | 1-0 | Real Salt Lake | |||
| 65 | Barnes | ||||
| Sporting Kansas City | 2-1 | Orlando City | |||
| 74 | Dwyer | 67(og) | Medranda | ||
| 79 | Peterson | ||||
| Portland Timbers | 1-2 | New York City | |||
| 55 | Adi | 12 | Villa | ||
| 65 | McNamara | ||||
