| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
| 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 263 | 676 | 2.57 | 110 | 41.83% | 70 | 26.62% | 83 | 31.56% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Louisville City | 19 | 12 | 6 | 1 | 37 | 17 | +20 | 42 | WXWO | 9 | 4 | 4 | 1 | 17 | 9 | 10 | 8 | 2 | 0 | 20 | 8 | ||
| 2 | New York Red Bulls 2 | 18 | 12 | 5 | 1 | 31 | 12 | +19 | 41 | WWWO | 9 | 4 | 4 | 1 | 13 | 5 | 9 | 8 | 1 | 0 | 18 | 7 | ||
| 3 | FC Cincinnati | 18 | 10 | 4 | 4 | 26 | 18 | +8 | 34 | LWLW | 10 | 6 | 2 | 2 | 15 | 10 | 8 | 4 | 2 | 2 | 11 | 8 | ||
| 4 | Charleston Battery | 18 | 9 | 5 | 4 | 22 | 16 | +6 | 32 | OXWW | 9 | 5 | 2 | 2 | 10 | 6 | 9 | 4 | 3 | 2 | 12 | 10 | ||
| 5 | Rochester Rhinos | 18 | 8 | 6 | 4 | 22 | 16 | +6 | 30 | XWOW | 10 | 6 | 3 | 1 | 16 | 10 | 8 | 2 | 3 | 3 | 6 | 6 | ||
| 6 | 2 | Richmond Kickers | 18 | 7 | 5 | 6 | 20 | 15 | +5 | 26 | WWLO | 8 | 5 | 2 | 1 | 10 | 4 | 10 | 2 | 3 | 5 | 10 | 11 | |
| 7 | 1 | Charlotte Independence | 17 | 7 | 4 | 6 | 23 | 20 | +3 | 25 | LLXW | 10 | 5 | 1 | 4 | 14 | 13 | 7 | 2 | 3 | 2 | 9 | 7 | |
| 8 | 2 | Bethlehem Steel | 18 | 6 | 6 | 6 | 20 | 21 | -1 | 24 | WWLL | 8 | 4 | 2 | 2 | 10 | 5 | 10 | 2 | 4 | 4 | 10 | 16 | |
| 9 | 2 | Orlando City B | 18 | 6 | 6 | 6 | 24 | 26 | -2 | 24 | OOXW | 11 | 3 | 4 | 4 | 15 | 17 | 7 | 3 | 2 | 2 | 9 | 9 | |
| 10 | 1 | Wilmington Hammerheads | 18 | 6 | 5 | 7 | 22 | 26 | -4 | 23 | LLWW | 9 | 3 | 3 | 3 | 11 | 10 | 9 | 3 | 2 | 4 | 11 | 16 | |
| 11 | Toronto FC 2 | 21 | 5 | 5 | 11 | 26 | 38 | -12 | 20 | XWWL | 10 | 3 | 3 | 4 | 12 | 15 | 11 | 2 | 2 | 7 | 14 | 23 | ||
| 12 | Harrisburg City | 20 | 5 | 2 | 13 | 25 | 38 | -13 | 17 | WLLO | 10 | 3 | 1 | 6 | 17 | 23 | 10 | 2 | 1 | 7 | 8 | 15 | ||
| 13 | Pittsburgh Riverhounds | 17 | 2 | 4 | 11 | 15 | 28 | -13 | 10 | LLLO | 9 | 2 | 1 | 6 | 8 | 14 | 8 | 0 | 3 | 5 | 7 | 14 | ||
| 14 | FC Montréal | 18 | 2 | 1 | 15 | 15 | 34 | -19 | 7 | LLLL | 6 | 0 | 0 | 6 | 4 | 13 | 12 | 2 | 1 | 9 | 11 | 21 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | 1 | LA Galaxy 2 | 18 | 8 | 8 | 2 | 37 | 23 | +14 | 32 | WWWX | 11 | 6 | 4 | 1 | 20 | 10 | 7 | 2 | 4 | 1 | 17 | 13 | |
| 2 | 2 | Colorado Springs | 18 | 9 | 4 | 5 | 23 | 14 | +9 | 31 | XWLX | 9 | 6 | 2 | 1 | 10 | 3 | 9 | 3 | 2 | 4 | 13 | 11 | |
| 3 | 2 | Sacramento Republic | 18 | 8 | 5 | 5 | 23 | 18 | +5 | 29 | LXLW | 10 | 5 | 2 | 3 | 14 | 11 | 8 | 3 | 3 | 2 | 9 | 7 | |
| 4 | 1 | OKC Energy | 16 | 7 | 7 | 2 | 20 | 13 | +7 | 28 | WWOO | 8 | 3 | 4 | 1 | 11 | 8 | 8 | 4 | 3 | 1 | 9 | 5 | |
| 5 | 2 | RGV Toros | 19 | 7 | 7 | 5 | 26 | 21 | +5 | 28 | WOOL | 9 | 4 | 3 | 2 | 15 | 7 | 10 | 3 | 4 | 3 | 11 | 14 | |
| 6 | 3 | San Antonio | 17 | 6 | 6 | 5 | 21 | 16 | +5 | 24 | WOWW | 9 | 4 | 3 | 2 | 13 | 9 | 8 | 2 | 3 | 3 | 8 | 7 | |
| 7 | 1 | Swope Park Rangers | 18 | 6 | 4 | 8 | 23 | 27 | -4 | 22 | XLXW | 7 | 4 | 0 | 3 | 11 | 9 | 11 | 2 | 4 | 5 | 12 | 18 | |
| 8 | 1 | Real Monarchs | 19 | 6 | 4 | 9 | 20 | 24 | -4 | 22 | WLLW | 8 | 2 | 2 | 4 | 9 | 10 | 11 | 4 | 2 | 5 | 11 | 14 | |
| 9 | 3 | Orange County SC | 18 | 6 | 4 | 8 | 23 | 28 | -5 | 22 | LXLW | 9 | 4 | 2 | 3 | 13 | 13 | 9 | 2 | 2 | 5 | 10 | 15 | |
| 10 | 2 | Seattle Sounders-2 | 19 | 5 | 5 | 9 | 20 | 31 | -11 | 20 | WWXL | 11 | 3 | 3 | 5 | 11 | 17 | 8 | 2 | 2 | 4 | 9 | 14 | |
| 11 | 1 | Portland Timbers 2 | 18 | 5 | 3 | 10 | 17 | 25 | -8 | 18 | LXLL | 11 | 4 | 2 | 5 | 13 | 18 | 7 | 1 | 1 | 5 | 4 | 7 | |
| 12 | 1 | Arizona United | 17 | 4 | 6 | 7 | 18 | 24 | -6 | 18 | LXLX | 8 | 2 | 4 | 2 | 10 | 10 | 9 | 2 | 2 | 5 | 8 | 14 | |
| 13 | Tulsa Roughnecks | 18 | 4 | 3 | 11 | 20 | 36 | -16 | 15 | WOLW | 10 | 3 | 1 | 6 | 13 | 18 | 8 | 1 | 2 | 5 | 7 | 18 | ||
| 14 | +2 | Chandler HOFFMAN (Louisville City, 3p) |
| +1 | Jack McBEAN (LA Galaxy 2, 4p) | |
| 10 | Kyle GREIG (Vancouver Whitecaps 2, 3p) | |
| 9 | +1 | Samuel OCHOA (Tulsa Roughnecks, 1p) |
| Irvin HERRERA (Saint Louis, 1p) | ||
| 8 | Brandon ALLEN (New York Red Bulls 2, 1p) | |
| Sean OKOLI (FC Cincinnati, 4p) | ||
| 7 | Romario WILLIAMS (Charleston Battery) | |
| Ricárdo VELAZCO (Real Monarchs, 1p) | ||
| Didier CRETTENAND (Orange County SC, 4p) | ||
| +2 | Christian VOLESKY (Rochester Rhinos, 1p) | |
| 6 | Raheem EDWARDS (Toronto FC 2, 1p) | |
| Cameron IWASA (Sacramento Republic) | ||
| Michael COX (Orlando City B) | ||
| 5 | +1 | Mike SETH (Colorado Springs) |
| Aaron WHEELER (Harrisburg City) | ||
| Daniel HABER (Vancouver Whitecaps 2) | ||
| +1 | BRUNO Caldini PERONE (Wilmington Hammerheads, 2p) | |
| +1 | TAN Long (Arizona United, 2p) | |
| Memo RODRIGUEZ (RGV Toros) | ||
| Junior FLEMMINGS (New York Red Bulls 2) | ||
| Mark GONZALEZ (Swope Park Rangers) | ||
| Martin MAYBIN (Colorado Springs) | ||
| Romeo PARKES (Pittsburgh Riverhounds, 1p) | ||
| Justin PORTILLO (Charleston Battery, 4p) | ||
| Neco BRETT (Portland Timbers 2) | ||
| José VILLARREAL (LA Galaxy 2, 1p) |
| Thursday, 14 July 2016 | |||||
| Pittsburgh Riverhounds | 0-2 | Richmond Kickers | |||
| 44(p) | Imura | ||||
| 67 | Jane | ||||
| Bethlehem Steel | 3-0 | Wilmington Hammerheads | |||
| 29 | Heard | ||||
| 42 | Jones | ||||
| 54 | Gissie | ||||
| Friday, 15 July 2016 | |||||
| Tulsa Roughnecks | 2-0 | Saint Louis | |||
| 66 | Villalobos | ||||
| 83 | Ochoa | ||||
| Saturday, 16 July 2016 | |||||
| Rochester Rhinos | 3-1 | FC Montréal | |||
| 32 | Volesky | 12 | Mkungilwa | ||
| 49 | Duba | ||||
| 79 | Fall | ||||
| San Antonio | 2-0 | Vancouver Whitecaps 2 | |||
| 64(p) | Castillo | ||||
| 90 | Tayou | ||||
| Arizona United | 2-3 | Seattle Sounders-2 | |||
| 29 | Cortez | 25 | Jones | ||
| 36 | Tan | 45 | Schweitzer | ||
| 56 | Jones | ||||
| OKC Energy | 2-1 | Orange County SC | |||
| 22 | Thomas | 26 | Caesar | ||
| 35 | Wójcik | ||||
| Charlotte Independence | 1-2 | New York Red Bulls 2 | |||
| 49 | Davidson | 14 | Bonomo | ||
| 64 | Metzger | ||||
| Colorado Springs | 1-0 | Sacramento Republic | |||
| 83 | Greer | ||||
| Portland Timbers 2 | 1-4 | LA Galaxy 2 | |||
| 35 | Clarke | 6 | Nishanian | ||
| 18 | Rebellón | ||||
| 39 | Mendiola | ||||
| 75 | McBean | ||||
| Sunday, 17 July 2016 | |||||
| Pittsburgh Riverhounds | 1-2 | Harrisburg City | |||
| 60 | Kerr | 28 | Leverock | ||
| 33 | Barril | ||||
| Wilmington Hammerheads | 1-4 | Louisville City | |||
| 88(p) | Bruno Perone | 12 | Abend | ||
| 64(p) | Hoffman | ||||
| 69 | Quinn | ||||
| 80 | Hoffman | ||||
| Wednesday, 20 July 2016 | |||||
| Colorado Springs | 1-1 | Swope Park Rangers | |||
| 61 | Seth | 90 | Molano | ||
| Toronto FC 2 | 1-1 | Rochester Rhinos | |||
| 77 | Thomas | 27 | Volesky | ||
| FC Cincinnati | 1-2 | New York Red Bulls 2 | |||
| 61 | McLaughlin | 83 | Bilyeu | ||
| 86 | Valot | ||||