| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
| 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 206 | 528 | 2.56 | 89 | 43.20% | 55 | 26.70% | 62 | 30.10% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Louisville City | 16 | 10 | 5 | 1 | 30 | 15 | +15 | 35 | OWWX | 7 | 3 | 3 | 1 | 14 | 8 | 9 | 7 | 2 | 0 | 16 | 7 | ||
| 2 | New York Red Bulls 2 | 13 | 8 | 4 | 1 | 19 | 8 | +11 | 28 | XWWW | 7 | 3 | 3 | 1 | 9 | 5 | 6 | 5 | 1 | 0 | 10 | 3 | ||
| 3 | FC Cincinnati | 14 | 8 | 4 | 2 | 21 | 13 | +8 | 28 | OWWX | 8 | 5 | 2 | 1 | 13 | 8 | 6 | 3 | 2 | 1 | 8 | 5 | ||
| 4 | 1 | Charlotte Independence | 14 | 7 | 3 | 4 | 20 | 15 | +5 | 24 | WWLX | 8 | 5 | 1 | 2 | 12 | 9 | 6 | 2 | 2 | 2 | 8 | 6 | |
| 5 | 1 | Charleston Battery | 14 | 7 | 3 | 4 | 18 | 15 | +3 | 24 | WLWL | 7 | 4 | 1 | 2 | 8 | 6 | 7 | 3 | 2 | 2 | 10 | 9 | |
| 6 | 1 | Rochester Rhinos | 13 | 6 | 3 | 4 | 16 | 13 | +3 | 21 | WLLW | 7 | 4 | 2 | 1 | 11 | 8 | 6 | 2 | 1 | 3 | 5 | 5 | |
| 7 | 1 | Richmond Kickers | 15 | 5 | 5 | 5 | 15 | 13 | +2 | 20 | OLWX | 8 | 5 | 2 | 1 | 10 | 4 | 7 | 0 | 3 | 4 | 5 | 9 | |
| 8 | Orlando City B | 14 | 5 | 3 | 6 | 20 | 24 | -4 | 18 | XWLW | 10 | 3 | 3 | 4 | 14 | 16 | 4 | 2 | 0 | 2 | 6 | 8 | ||
| 9 | 1 | Bethlehem Steel | 14 | 4 | 6 | 4 | 13 | 17 | -4 | 18 | OXWL | 6 | 2 | 2 | 2 | 5 | 5 | 8 | 2 | 4 | 2 | 8 | 12 | |
| 10 | 1 | Wilmington Hammerheads | 13 | 4 | 5 | 4 | 16 | 14 | +2 | 17 | XXWW | 7 | 2 | 3 | 2 | 7 | 6 | 6 | 2 | 2 | 2 | 9 | 8 | |
| 11 | Harrisburg City | 16 | 4 | 1 | 11 | 21 | 30 | -9 | 13 | LLLL | 8 | 3 | 1 | 4 | 15 | 16 | 8 | 1 | 0 | 7 | 6 | 14 | ||
| 12 | Toronto FC 2 | 16 | 3 | 4 | 9 | 18 | 29 | -11 | 13 | LLXW | 7 | 2 | 2 | 3 | 8 | 11 | 9 | 1 | 2 | 6 | 10 | 18 | ||
| 13 | Pittsburgh Riverhounds | 13 | 2 | 3 | 8 | 14 | 22 | -8 | 9 | LWLL | 6 | 2 | 0 | 4 | 7 | 10 | 7 | 0 | 3 | 4 | 7 | 12 | ||
| 14 | FC Montréal | 14 | 2 | 1 | 11 | 11 | 22 | -11 | 7 | WLXL | 4 | 0 | 0 | 4 | 1 | 6 | 10 | 2 | 1 | 7 | 10 | 16 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | 2 | LA Galaxy 2 | 16 | 6 | 8 | 2 | 31 | 21 | +10 | 26 | WXOX | 10 | 5 | 4 | 1 | 18 | 9 | 6 | 1 | 4 | 1 | 13 | 12 | |
| 2 | 1 | Sacramento Republic | 14 | 7 | 4 | 3 | 16 | 10 | +6 | 25 | XWWW | 8 | 4 | 2 | 2 | 10 | 7 | 6 | 3 | 2 | 1 | 6 | 3 | |
| 3 | 1 | Colorado Springs | 12 | 7 | 2 | 3 | 18 | 9 | +9 | 23 | LOWX | 5 | 4 | 1 | 0 | 7 | 1 | 7 | 3 | 1 | 3 | 11 | 8 | |
| 4 | RGV Toros | 15 | 6 | 5 | 4 | 21 | 19 | +2 | 23 | XLWL | 6 | 3 | 2 | 1 | 10 | 5 | 9 | 3 | 3 | 3 | 11 | 14 | ||
| 5 | OKC Energy | 12 | 5 | 5 | 2 | 16 | 12 | +4 | 20 | XWLW | 6 | 2 | 3 | 1 | 9 | 7 | 6 | 3 | 2 | 1 | 7 | 5 | ||
| 6 | Orange County SC | 14 | 5 | 3 | 6 | 16 | 20 | -4 | 18 | LWLW | 8 | 4 | 1 | 3 | 10 | 10 | 6 | 1 | 2 | 3 | 6 | 10 | ||
| 7 | Portland Timbers 2 | 16 | 5 | 2 | 9 | 15 | 20 | -5 | 17 | LLLX | 9 | 4 | 1 | 4 | 11 | 13 | 7 | 1 | 1 | 5 | 4 | 7 | ||
| 8 | 3 | San Antonio | 14 | 4 | 5 | 5 | 17 | 15 | +2 | 17 | WWXL | 7 | 3 | 2 | 2 | 11 | 9 | 7 | 1 | 3 | 3 | 6 | 6 | |
| 9 | Arizona United | 14 | 4 | 5 | 5 | 13 | 17 | -4 | 17 | XXWW | 6 | 2 | 3 | 1 | 7 | 6 | 8 | 2 | 2 | 4 | 6 | 11 | ||
| 10 | 2 | Real Monarchs | 15 | 4 | 4 | 7 | 15 | 19 | -4 | 16 | LLLW | 7 | 2 | 2 | 3 | 8 | 8 | 8 | 2 | 2 | 4 | 7 | 11 | |
| 11 | 1 | Swope Park Rangers | 13 | 4 | 2 | 7 | 18 | 23 | -5 | 14 | LLWL | 5 | 3 | 0 | 2 | 10 | 7 | 8 | 1 | 2 | 5 | 8 | 16 | |
| 12 | Seattle Sounders-2 | 14 | 3 | 4 | 7 | 13 | 23 | -10 | 13 | WWLL | 9 | 2 | 3 | 4 | 9 | 14 | 5 | 1 | 1 | 3 | 4 | 9 | ||
| 13 | Tulsa Roughnecks | 14 | 2 | 2 | 10 | 14 | 32 | -18 | 8 | LXLL | 7 | 1 | 1 | 5 | 7 | 14 | 7 | 1 | 1 | 5 | 7 | 18 | ||
| 12 | Jack McBEAN (LA Galaxy 2, 3p) | |
| 10 | Chandler HOFFMAN (Louisville City, 2p) | |
| Kyle GREIG (Vancouver Whitecaps 2, 3p) | ||
| 9 | +1 | Irvin HERRERA (Saint Louis, 1p) |
| 7 | Samuel OCHOA (Tulsa Roughnecks, 1p) | |
| Sean OKOLI (FC Cincinnati, 3p) | ||
| 6 | Romario WILLIAMS (Charleston Battery) | |
| Ricárdo VELAZCO (Real Monarchs, 1p) | ||
| 5 | +2 | Aaron WHEELER (Harrisburg City) |
| Raheem EDWARDS (Toronto FC 2, 1p) | ||
| Cameron IWASA (Sacramento Republic) | ||
| Martin MAYBIN (Colorado Springs) | ||
| Romeo PARKES (Pittsburgh Riverhounds, 1p) | ||
| Justin PORTILLO (Charleston Battery, 4p) | ||
| Neco BRETT (Portland Timbers 2) | ||
| Christian VOLESKY (Rochester Rhinos, 1p) | ||
| José VILLARREAL (LA Galaxy 2, 1p) | ||
| Michael COX (Orlando City B) |
| Sunday, 19 June 2016 | |||||
| Vancouver Whitecaps 2 | 1-0 | Portland Timbers 2 | |||
| 87 | Haber | ||||
| Orlando City B | 2-2 | New York Red Bulls 2 | |||
| 17 | García | 37 | Schmoll | ||
| 87 | Da Silva | 41 | Long | ||
| Tuesday, 21 June 2016 | |||||
| Harrisburg City | 2-3 | FC Montréal | |||
| 77 | Wheeler | 30 | Kacher | ||
| 82 | Wheeler | 51 | Sukunda | ||
| 54 | Jackson-Hamel | ||||
| Louisville City | 4-1 | Toronto FC 2 | |||
| 11 | Abend | 79 | Hundal | ||
| 24 | Abend | ||||
| 26 | McCabe | ||||
| 65 | Morad | ||||
| Wednesday, 22 June 2016 | |||||
| RGV Toros | 1-1 | Arizona United | |||
| 20 | Bird | 63 | Blackwood | ||
| Thursday, 23 June 2016 | |||||
| San Antonio | 3-2 | Orange County SC | |||
| 17 | Reed | 41 | Meeus | ||
| 74 | Tayou | 47 | Crettenand | ||
| 80 | Palacios | ||||
| Friday, 24 June 2016 | |||||
| LA Galaxy 2 | 2-0 | Tulsa Roughnecks | |||
| 7 | Amaya | ||||
| 47(p) | Covarrubias | ||||
| Saturday, 25 June 2016 | |||||
| Richmond Kickers | 0-0 | Bethlehem Steel | |||
| Rochester Rhinos | 2-1 | Pittsburgh Riverhounds | |||
| 7 | Farrell | 45 | Hertzog | ||
| 60 | Garzi | ||||
| Harrisburg City | 1-3 | Charlotte Independence | |||
| 10 | Foster | 53(p) | Martínez | ||
| 60 | Estrada | ||||
| 86 | Hilton | ||||
| Arizona United | 1-1 | Sacramento Republic | |||
| 54 | Blackwood | 90 | Pridham | ||
| OKC Energy | 1-1 | Vancouver Whitecaps 2 | |||
| 45 | Craft | 26 | Safiu | ||
| Louisville City | 0-0 | FC Cincinnati | |||
| Saint Louis | 1-0 | Portland Timbers 2 | |||
| 57(p) | Herrera | ||||