| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
| 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 248 | 631 | 2.54 | 104 | 41.94% | 68 | 27.42% | 76 | 30.65% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Louisville City | 18 | 11 | 6 | 1 | 33 | 16 | +17 | 39 | XWOW | 9 | 4 | 4 | 1 | 17 | 9 | 9 | 7 | 2 | 0 | 16 | 7 | ||
| 2 | New York Red Bulls 2 | 16 | 10 | 5 | 1 | 27 | 10 | +17 | 35 | WOWX | 9 | 4 | 4 | 1 | 13 | 5 | 7 | 6 | 1 | 0 | 14 | 5 | ||
| 3 | FC Cincinnati | 17 | 10 | 4 | 3 | 25 | 16 | +9 | 34 | WLWO | 9 | 6 | 2 | 1 | 14 | 8 | 8 | 4 | 2 | 2 | 11 | 8 | ||
| 4 | Charleston Battery | 18 | 9 | 5 | 4 | 22 | 16 | +6 | 32 | OXWW | 9 | 5 | 2 | 2 | 10 | 6 | 9 | 4 | 3 | 2 | 12 | 10 | ||
| 5 | 1 | Rochester Rhinos | 16 | 7 | 5 | 4 | 18 | 14 | +4 | 26 | OWOW | 9 | 5 | 3 | 1 | 13 | 9 | 7 | 2 | 2 | 3 | 5 | 5 | |
| 6 | 1 | Charlotte Independence | 16 | 7 | 4 | 5 | 22 | 18 | +4 | 25 | LXWW | 9 | 5 | 1 | 3 | 13 | 11 | 7 | 2 | 3 | 2 | 9 | 7 | |
| 7 | 1 | Orlando City B | 18 | 6 | 6 | 6 | 24 | 26 | -2 | 24 | OOXW | 11 | 3 | 4 | 4 | 15 | 17 | 7 | 3 | 2 | 2 | 9 | 9 | |
| 8 | 1 | Richmond Kickers | 17 | 6 | 5 | 6 | 18 | 15 | +3 | 23 | WLOL | 8 | 5 | 2 | 1 | 10 | 4 | 9 | 1 | 3 | 5 | 8 | 11 | |
| 9 | Wilmington Hammerheads | 16 | 6 | 5 | 5 | 21 | 19 | +2 | 23 | WWLX | 8 | 3 | 3 | 2 | 10 | 6 | 8 | 3 | 2 | 3 | 11 | 13 | ||
| 10 | Bethlehem Steel | 17 | 5 | 6 | 6 | 17 | 21 | -4 | 21 | WLLO | 7 | 3 | 2 | 2 | 7 | 5 | 10 | 2 | 4 | 4 | 10 | 16 | ||
| 11 | Toronto FC 2 | 20 | 5 | 4 | 11 | 25 | 37 | -12 | 19 | WWLL | 9 | 3 | 2 | 4 | 11 | 14 | 11 | 2 | 2 | 7 | 14 | 23 | ||
| 12 | Harrisburg City | 19 | 4 | 2 | 13 | 23 | 37 | -14 | 14 | LLOL | 10 | 3 | 1 | 6 | 17 | 23 | 9 | 1 | 1 | 7 | 6 | 14 | ||
| 13 | Pittsburgh Riverhounds | 15 | 2 | 4 | 9 | 14 | 24 | -10 | 10 | LOLW | 7 | 2 | 1 | 4 | 7 | 10 | 8 | 0 | 3 | 5 | 7 | 14 | ||
| 14 | FC Montréal | 17 | 2 | 1 | 14 | 14 | 31 | -17 | 7 | LLLW | 6 | 0 | 0 | 6 | 4 | 13 | 11 | 2 | 1 | 8 | 10 | 18 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | 1 | Sacramento Republic | 17 | 8 | 5 | 4 | 23 | 17 | +6 | 29 | XLWX | 10 | 5 | 2 | 3 | 14 | 11 | 7 | 3 | 3 | 1 | 9 | 6 | |
| 2 | 1 | LA Galaxy 2 | 17 | 7 | 8 | 2 | 33 | 22 | +11 | 29 | WWXO | 11 | 6 | 4 | 1 | 20 | 10 | 6 | 1 | 4 | 1 | 13 | 12 | |
| 3 | 1 | RGV Toros | 19 | 7 | 7 | 5 | 26 | 21 | +5 | 28 | WOOL | 9 | 4 | 3 | 2 | 15 | 7 | 10 | 3 | 4 | 3 | 11 | 14 | |
| 4 | 1 | Colorado Springs | 16 | 8 | 3 | 5 | 21 | 13 | +8 | 27 | LXWL | 7 | 5 | 1 | 1 | 8 | 2 | 9 | 3 | 2 | 4 | 13 | 11 | |
| 5 | 2 | OKC Energy | 15 | 6 | 7 | 2 | 18 | 12 | +6 | 25 | WOOX | 7 | 2 | 4 | 1 | 9 | 7 | 8 | 4 | 3 | 1 | 9 | 5 | |
| 6 | Orange County SC | 17 | 6 | 4 | 7 | 22 | 26 | -4 | 22 | XLWL | 9 | 4 | 2 | 3 | 13 | 13 | 8 | 2 | 2 | 4 | 9 | 13 | ||
| 7 | 2 | Real Monarchs | 19 | 6 | 4 | 9 | 20 | 24 | -4 | 22 | WLLW | 8 | 2 | 2 | 4 | 9 | 10 | 11 | 4 | 2 | 5 | 11 | 14 | |
| 8 | Swope Park Rangers | 17 | 6 | 3 | 8 | 22 | 26 | -4 | 21 | LXWW | 7 | 4 | 0 | 3 | 11 | 9 | 10 | 2 | 3 | 5 | 11 | 17 | ||
| 9 | San Antonio | 16 | 5 | 6 | 5 | 19 | 16 | +3 | 21 | OWWW | 8 | 3 | 3 | 2 | 11 | 9 | 8 | 2 | 3 | 3 | 8 | 7 | ||
| 10 | Portland Timbers 2 | 17 | 5 | 3 | 9 | 16 | 21 | -5 | 18 | XLLL | 10 | 4 | 2 | 4 | 12 | 14 | 7 | 1 | 1 | 5 | 4 | 7 | ||
| 11 | Arizona United | 16 | 4 | 6 | 6 | 16 | 21 | -5 | 18 | XLXX | 7 | 2 | 4 | 1 | 8 | 7 | 9 | 2 | 2 | 5 | 8 | 14 | ||
| 12 | Seattle Sounders-2 | 18 | 4 | 5 | 9 | 17 | 29 | -12 | 17 | WXLL | 11 | 3 | 3 | 5 | 11 | 17 | 7 | 1 | 2 | 4 | 6 | 12 | ||
| 13 | Tulsa Roughnecks | 17 | 3 | 3 | 11 | 18 | 36 | -18 | 12 | OLWL | 9 | 2 | 1 | 6 | 11 | 18 | 8 | 1 | 2 | 5 | 7 | 18 | ||
| 13 | Jack McBEAN (LA Galaxy 2, 4p) | |
| 12 | +1 | Chandler HOFFMAN (Louisville City, 2p) |
| 10 | Kyle GREIG (Vancouver Whitecaps 2, 3p) | |
| 9 | Irvin HERRERA (Saint Louis, 1p) | |
| 8 | Samuel OCHOA (Tulsa Roughnecks, 1p) | |
| +3 | Brandon ALLEN (New York Red Bulls 2, 1p) | |
| Sean OKOLI (FC Cincinnati, 4p) | ||
| 7 | Romario WILLIAMS (Charleston Battery) | |
| Ricárdo VELAZCO (Real Monarchs, 1p) | ||
| +2 | Didier CRETTENAND (Orange County SC, 4p) | |
| 6 | +1 | Raheem EDWARDS (Toronto FC 2, 1p) |
| +1 | Cameron IWASA (Sacramento Republic) | |
| Michael COX (Orlando City B) | ||
| 5 | Aaron WHEELER (Harrisburg City) | |
| Daniel HABER (Vancouver Whitecaps 2) | ||
| +2 | Memo RODRIGUEZ (RGV Toros) | |
| +1 | Junior FLEMMINGS (New York Red Bulls 2) | |
| Mark GONZALEZ (Swope Park Rangers) | ||
| Martin MAYBIN (Colorado Springs) | ||
| Romeo PARKES (Pittsburgh Riverhounds, 1p) | ||
| Justin PORTILLO (Charleston Battery, 4p) | ||
| Neco BRETT (Portland Timbers 2) | ||
| Christian VOLESKY (Rochester Rhinos, 1p) | ||
| José VILLARREAL (LA Galaxy 2, 1p) |
| Saturday, 9 July 2016 | |||||
| San Antonio | 0-0 | OKC Energy | |||
| Arizona United | 1-1 | Swope Park Rangers | |||
| 27(p) | Tan | 30(p) | Tyrpak | ||
| Charlotte Independence | 1-2 | Wilmington Hammerheads | |||
| 45 | Hilton | 44 | Townsend | ||
| 64 | Martz | ||||
| Louisville City | 1-1 | Charleston Battery | |||
| 62 | Hoffman | 84 | Tsonis | ||
| FC Montréal | 2-4 | New York Red Bulls 2 | |||
| 41 | Tabla | 18(p) | Allen | ||
| 84 | Charbonneau | 24 | Allen | ||
| 47 | Flemmings | ||||
| 70 | Allen | ||||
| Saint Louis | 1-2 | FC Cincinnati | |||
| 85 | Tshuma | 8 | Cummings | ||
| 78 | Stevenson | ||||
| Sunday, 10 July 2016 | |||||
| Rochester Rhinos | 0-0 | Orlando City B | |||
| Harrisburg City | 2-4 | Toronto FC 2 | |||
| 58 | Pettis | 35 | Edwards | ||
| 69 | Barril | 48 | Akinola | ||
| 49 | Akinola | ||||
| 86 | Daniels | ||||
| Orange County SC | 3-3 | Sacramento Republic | |||
| 51(p) | Crettenand | 21 | Da Fonte | ||
| 71 | Caesar | 78 | Iwasa | ||
| 81 | Crettenand | 84 | Pridham | ||
| Seattle Sounders-2 | 2-1 | Colorado Springs | |||
| 60 | Jones | 27 | Seth | ||
| 85 | Mansaray | ||||
| RGV Toros | 0-0 | Tulsa Roughnecks | |||
| Bethlehem Steel | 2-0 | Pittsburgh Riverhounds | |||
| 24 | Burke | ||||
| 90(p) | Fernandes | ||||
| Tuesday, 12 July 2016 | |||||
| Swope Park Rangers | 0-2 | OKC Energy | |||
| 84 | Craft | ||||
| 89 | Pitter | ||||
| Wednesday, 13 July 2016 | |||||
| Charleston Battery | 0-0 | Orlando City B | |||
| RGV Toros | 4-0 | Vancouver Whitecaps 2 | |||
| 17 | Rodriguez | ||||
| 21 | Casner | ||||
| 40 | Rodriguez | ||||
| 89 | Garcia | ||||