| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
| 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 192 | 492 | 2.56 | 83 | 43.23% | 49 | 25.52% | 60 | 31.25% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Louisville City | 14 | 9 | 4 | 1 | 26 | 14 | +12 | 31 | WXWW | 5 | 2 | 2 | 1 | 10 | 7 | 9 | 7 | 2 | 0 | 16 | 7 | ||
| 2 | New York Red Bulls 2 | 12 | 8 | 3 | 1 | 17 | 6 | +11 | 27 | WWWW | 7 | 3 | 3 | 1 | 9 | 5 | 5 | 5 | 0 | 0 | 8 | 1 | ||
| 3 | FC Cincinnati | 13 | 8 | 3 | 2 | 21 | 13 | +8 | 27 | WWXW | 8 | 5 | 2 | 1 | 13 | 8 | 5 | 3 | 1 | 1 | 8 | 5 | ||
| 4 | Charleston Battery | 14 | 7 | 3 | 4 | 18 | 15 | +3 | 24 | WLWL | 7 | 4 | 1 | 2 | 8 | 6 | 7 | 3 | 2 | 2 | 10 | 9 | ||
| 5 | 2 | Charlotte Independence | 13 | 6 | 3 | 4 | 17 | 14 | +3 | 21 | WLXL | 8 | 5 | 1 | 2 | 12 | 9 | 5 | 1 | 2 | 2 | 5 | 5 | |
| 6 | 1 | Richmond Kickers | 14 | 5 | 4 | 5 | 15 | 13 | +2 | 19 | LWXL | 7 | 5 | 1 | 1 | 10 | 4 | 7 | 0 | 3 | 4 | 5 | 9 | |
| 7 | 1 | Rochester Rhinos | 12 | 5 | 3 | 4 | 14 | 12 | +2 | 18 | LLWX | 6 | 3 | 2 | 1 | 9 | 7 | 6 | 2 | 1 | 3 | 5 | 5 | |
| 8 | Orlando City B | 13 | 5 | 2 | 6 | 18 | 22 | -4 | 17 | WLWW | 9 | 3 | 2 | 4 | 12 | 14 | 4 | 2 | 0 | 2 | 6 | 8 | ||
| 9 | Wilmington Hammerheads | 13 | 4 | 5 | 4 | 16 | 14 | +2 | 17 | XXWW | 7 | 2 | 3 | 2 | 7 | 6 | 6 | 2 | 2 | 2 | 9 | 8 | ||
| 10 | Bethlehem Steel | 13 | 4 | 5 | 4 | 13 | 17 | -4 | 17 | XWLX | 6 | 2 | 2 | 2 | 5 | 5 | 7 | 2 | 3 | 2 | 8 | 12 | ||
| 11 | Harrisburg City | 14 | 4 | 1 | 9 | 18 | 24 | -6 | 13 | LLLL | 6 | 3 | 1 | 2 | 12 | 10 | 8 | 1 | 0 | 7 | 6 | 14 | ||
| 12 | Toronto FC 2 | 15 | 3 | 4 | 8 | 17 | 25 | -8 | 13 | LXWX | 7 | 2 | 2 | 3 | 8 | 11 | 8 | 1 | 2 | 5 | 9 | 14 | ||
| 13 | Pittsburgh Riverhounds | 12 | 2 | 3 | 7 | 13 | 20 | -7 | 9 | WLLL | 6 | 2 | 0 | 4 | 7 | 10 | 6 | 0 | 3 | 3 | 6 | 10 | ||
| 14 | FC Montréal | 13 | 1 | 1 | 11 | 8 | 20 | -12 | 4 | LXLL | 4 | 0 | 0 | 4 | 1 | 6 | 9 | 1 | 1 | 7 | 7 | 14 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | 3 | Sacramento Republic | 13 | 7 | 3 | 3 | 15 | 9 | +6 | 24 | WWWX | 8 | 4 | 2 | 2 | 10 | 7 | 5 | 3 | 1 | 1 | 5 | 2 | |
| 2 | 1 | Colorado Springs | 12 | 7 | 2 | 3 | 18 | 9 | +9 | 23 | LOWX | 5 | 4 | 1 | 0 | 7 | 1 | 7 | 3 | 1 | 3 | 11 | 8 | |
| 3 | LA Galaxy 2 | 15 | 5 | 8 | 2 | 29 | 21 | +8 | 23 | XOXW | 9 | 4 | 4 | 1 | 16 | 9 | 6 | 1 | 4 | 1 | 13 | 12 | ||
| 4 | 2 | RGV Toros | 14 | 6 | 4 | 4 | 20 | 18 | +2 | 22 | LWLW | 5 | 3 | 1 | 1 | 9 | 4 | 9 | 3 | 3 | 3 | 11 | 14 | |
| 5 | 1 | OKC Energy | 11 | 5 | 4 | 2 | 15 | 11 | +4 | 19 | WLWW | 5 | 2 | 2 | 1 | 8 | 6 | 6 | 3 | 2 | 1 | 7 | 5 | |
| 6 | 2 | Orange County SC | 13 | 5 | 3 | 5 | 14 | 17 | -3 | 18 | WLWX | 8 | 4 | 1 | 3 | 10 | 10 | 5 | 1 | 2 | 2 | 4 | 7 | |
| 7 | 2 | Portland Timbers 2 | 14 | 5 | 2 | 7 | 15 | 18 | -3 | 17 | LXWW | 9 | 4 | 1 | 4 | 11 | 13 | 5 | 1 | 1 | 3 | 4 | 5 | |
| 8 | 1 | Real Monarchs | 15 | 4 | 4 | 7 | 15 | 19 | -4 | 16 | LLLW | 7 | 2 | 2 | 3 | 8 | 8 | 8 | 2 | 2 | 4 | 7 | 11 | |
| 9 | 1 | Arizona United | 12 | 4 | 3 | 5 | 11 | 15 | -4 | 15 | WWLL | 5 | 2 | 2 | 1 | 6 | 5 | 7 | 2 | 1 | 4 | 5 | 10 | |
| 10 | 1 | Swope Park Rangers | 13 | 4 | 2 | 7 | 18 | 23 | -5 | 14 | LLWL | 5 | 3 | 0 | 2 | 10 | 7 | 8 | 1 | 2 | 5 | 8 | 16 | |
| 11 | San Antonio | 13 | 3 | 5 | 5 | 14 | 13 | +1 | 14 | WXLO | 6 | 2 | 2 | 2 | 8 | 7 | 7 | 1 | 3 | 3 | 6 | 6 | ||
| 12 | Seattle Sounders-2 | 14 | 3 | 4 | 7 | 13 | 23 | -10 | 13 | WWLL | 9 | 2 | 3 | 4 | 9 | 14 | 5 | 1 | 1 | 3 | 4 | 9 | ||
| 13 | Tulsa Roughnecks | 13 | 2 | 2 | 9 | 14 | 30 | -16 | 8 | XLLL | 7 | 1 | 1 | 5 | 7 | 14 | 6 | 1 | 1 | 4 | 7 | 16 | ||
| 12 | +1 | Jack McBEAN (LA Galaxy 2, 3p) |
| 10 | Chandler HOFFMAN (Louisville City, 2p) | |
| Kyle GREIG (Vancouver Whitecaps 2, 3p) | ||
| 8 | Irvin HERRERA (Saint Louis) | |
| 7 | +1 | Samuel OCHOA (Tulsa Roughnecks, 1p) |
| Sean OKOLI (FC Cincinnati, 3p) | ||
| 6 | Romario WILLIAMS (Charleston Battery) | |
| Ricárdo VELAZCO (Real Monarchs, 1p) | ||
| 5 | +1 | Raheem EDWARDS (Toronto FC 2, 1p) |
| +2 | Cameron IWASA (Sacramento Republic) | |
| Martin MAYBIN (Colorado Springs) | ||
| Romeo PARKES (Pittsburgh Riverhounds, 1p) | ||
| +1 | Justin PORTILLO (Charleston Battery, 4p) | |
| Neco BRETT (Portland Timbers 2) | ||
| Christian VOLESKY (Rochester Rhinos, 1p) | ||
| José VILLARREAL (LA Galaxy 2, 1p) | ||
| Michael COX (Orlando City B) | ||
| 4 | +1 | Ashani FAIRCLOUGH (Wilmington Hammerheads) |
| BRUNO Caldini PERONE (Wilmington Hammerheads, 1p) | ||
| Dániel SALLÓI (Swope Park Rangers) | ||
| Mark GONZALEZ (Swope Park Rangers) | ||
| Paul WILSON (Harrisburg City) | ||
| Malik JOHNSON (Toronto FC 2, 1p) | ||
| Jorge HERRERA (Charlotte Independence, 1p) | ||
| Brandon ALLEN (New York Red Bulls 2) | ||
| Vince CICCIARELLA (Saint Louis) | ||
| +1 | Caleb CALVERT (Charlotte Independence) |
| Tuesday, 14 June 2016 | |||||
| Portland Timbers 2 | 1-2 | Seattle Sounders-2 | |||
| 67 | Bodily | 35 | Samuel | ||
| 43 | Magnus | ||||
| Wednesday, 15 June 2016 | |||||
| Toronto FC 2 | 1-1 | FC Montréal | |||
| 90 | Fraser | 55 | Jackson-Hamel | ||
| Friday, 17 June 2016 | |||||
| Wilmington Hammerheads | 1-1 | Bethlehem Steel | |||
| 48 | Fairclough | 19 | Conneh | ||
| Tulsa Roughnecks | 2-2 | LA Galaxy 2 | |||
| 41(p) | Ochoa | 1 | Payeras | ||
| 47(og) | Sneddon | 23 | McBean | ||
| Saturday, 18 June 2016 | |||||
| Rochester Rhinos | 0-1 | Louisville City | |||
| 28 | Lubahn | ||||
| Charleston Battery | 1-0 | Harrisburg City | |||
| 82(p) | Portillo | ||||
| Pittsburgh Riverhounds | 2-1 | FC Montréal | |||
| 18 | Kerr | 26 | Jackson-Hamel | ||
| 27 | Hertzog | ||||
| Orange County SC | 1-0 | Real Monarchs | |||
| 22(p) | Meeus | ||||
| San Antonio | 2-1 | Colorado Springs | |||
| 8 | Kaka | 50(p) | Vercollone | ||
| 35 | McCarthy | ||||
| Arizona United | 2-1 | Saint Louis | |||
| 10 | Blackwood | 90 | Roberts | ||
| 58 | Tan | ||||
| Sacramento Republic | 3-2 | RGV Toros | |||
| 1 | Iwasa | 14 | Rodriguez | ||
| 54 | Iwasa | 71 | Bird | ||
| 87 | Klimenta | ||||
| Charlotte Independence | 1-0 | Richmond Kickers | |||
| 30 | Calvert | ||||
| Swope Park Rangers | 1-3 | OKC Energy | |||
| 7 | Ayrton | 45 | Thomas | ||
| 64 | Wójcik | ||||
| 74 | Gonzalez | ||||
| FC Cincinnati | 2-1 | Toronto FC 2 | |||
| 61 | Delbridge | 4 | Edwards | ||
| 62 | Stevenson | ||||