| ROUND | R1 | QF | SF | F | ||||
| l1 | l2 | l1 | l2 | l1 | l2 | l1 | l2 | |
| Season archive |
| Tuesday, 15 March 2022 | ||||||
| qfl2 |  Comunicaciones | 4-2 | New York City | 5-5 | ||
| 45 | Lezcano | 32 | Castellanos | |||
| 69 | Samayoa | 53 | Talles Magno | |||
| 72 | García | |||||
| 89 | Contreras | |||||
| Wednesday, 16 March 2022 | ||||||
| qfl2 |  UNAM | 3-0 | New England Revolution | 3-3, p4-3 | ||
| 33 | Dinenno | |||||
| 49 | Dinenno | |||||
| 59 | Saucedo | |||||
| qfl2 | CF Montréal | 1-1 | Cruz Azul | 1-2 | ||
| 79 | Camacho | 44 | Antuna | |||
| Thursday, 17 March 2022 | ||||||
| qfl2 | León | 1-1 | Seattle Sounders | 1-4 | ||
| 90 | Ambriz | 45(p) | Montero | |||
| 5 | +2 | Juan DINENNO (UNAM) |
| 4 | +1 | Valentín CASTELLANOS (New York City, 1p) |
| 3 | +1 | TALLES MAGNO Bacelar (New York City) |
| +1 | Fredy MONTERO (Seattle Sounders, 2p) | |
| 2 | +1 | Uriel ANTUNA (Cruz Azul) |
| Adam BUKSA (New England Revolution) | ||
| Cristian BOLAÑOS (Saprissa, 1p) | ||
| Jordan MORRIS (Seattle Sounders) | ||
| Elías HERNÁNDEZ (León) |
