Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
| 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 188 | 522 | 2.77 | 94 | 50.00% | 50 | 26.60% | 44 | 23.40% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Columbus Crew | 27 | 16 | 5 | 6 | 46 | 31 | +15 | 53 | WWWX | 14 | 10 | 2 | 2 | 29 | 15 | 13 | 6 | 3 | 4 | 17 | 16 | ||
| 2 | New England Revolution | 27 | 12 | 7 | 8 | 38 | 37 | +1 | 43 | XLXW | 14 | 6 | 4 | 4 | 23 | 17 | 13 | 6 | 3 | 4 | 15 | 20 | ||
| 3 | Chicago Fire | 27 | 12 | 6 | 9 | 35 | 26 | +9 | 42 | XWLL | 13 | 6 | 2 | 5 | 16 | 13 | 14 | 6 | 4 | 4 | 19 | 13 | ||
| 4 | New York Red Bulls | 27 | 9 | 8 | 10 | 36 | 41 | -5 | 35 | LLLW | 14 | 8 | 3 | 3 | 27 | 19 | 13 | 1 | 5 | 7 | 9 | 22 | ||
| 5 | 1 | Kansas City Wizards | 27 | 8 | 9 | 10 | 30 | 36 | -6 | 33 | XLWW | 13 | 7 | 4 | 2 | 18 | 13 | 14 | 1 | 5 | 8 | 12 | 23 | |
| 6 | 1 | D.C. United | 27 | 10 | 3 | 14 | 41 | 49 | -8 | 33 | LLLX | 14 | 8 | 2 | 4 | 30 | 18 | 13 | 2 | 1 | 10 | 11 | 31 | |
| 7 | Toronto FC | 27 | 8 | 7 | 12 | 29 | 37 | -8 | 31 | WXLX | 14 | 5 | 7 | 2 | 14 | 10 | 13 | 3 | 0 | 10 | 15 | 27 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Houston Dynamo | 26 | 11 | 10 | 5 | 39 | 30 | +9 | 43 | WXXW | 12 | 8 | 3 | 1 | 25 | 13 | 14 | 3 | 7 | 4 | 14 | 17 | ||
| 2 | Chivas USA | 27 | 11 | 6 | 10 | 37 | 38 | -1 | 39 | WWWL | 13 | 7 | 3 | 3 | 19 | 12 | 14 | 4 | 3 | 7 | 18 | 26 | ||
| 3 | 1 | Real Salt Lake | 27 | 9 | 8 | 10 | 35 | 36 | -1 | 35 | XWLL | 13 | 7 | 5 | 1 | 20 | 8 | 14 | 2 | 3 | 9 | 15 | 28 | |
| 4 | 1 | FC Dallas | 27 | 8 | 10 | 9 | 40 | 34 | +6 | 34 | XWWX | 14 | 5 | 5 | 4 | 21 | 17 | 13 | 3 | 5 | 5 | 19 | 17 | |
| 5 | 2 | Colorado Rapids | 27 | 10 | 4 | 13 | 39 | 40 | -1 | 34 | LWXW | 14 | 7 | 2 | 5 | 21 | 13 | 13 | 3 | 2 | 8 | 18 | 27 | |
| 6 | 1 | San Jose Earthquakes | 26 | 7 | 9 | 10 | 27 | 32 | -5 | 30 | XLXW | 13 | 5 | 4 | 4 | 20 | 18 | 13 | 2 | 5 | 6 | 7 | 14 | |
| 7 | 1 | LA Galaxy | 27 | 7 | 8 | 12 | 50 | 55 | -5 | 29 | LLWL | 13 | 5 | 4 | 4 | 30 | 23 | 14 | 2 | 4 | 8 | 20 | 32 | |
| 19 | Landon DONOVAN (LA Galaxy, 3p) | |
| 16 | +1 | Kenny COOPER (FC Dallas, 3p) |
| 13 | Edson BUDDLE (LA Galaxy) | |
| 12 | +2 | Brian CHING (Houston Dynamo) |
| 11 | Juan Pablo ÁNGEL (New York Red Bulls, 1p) | |
| Luciano EMILIO (D.C. United) | ||
| 10 | Jaime MORENO (D.C. United, 4p) | |
| 9 | +1 | Alejandro MORENO (Columbus Crew) |
| +2 | Chad BARRETT (Toronto FC) | |
| +1 | Conor CASEY (Colorado Rapids, 1p) | |
| 8 | +1 | Steve RALSTON (New England Revolution, 1p) |
| Jeff CUNNINGHAM (FC Dallas) | ||
| 7 | +1 | Taylor TWELLMAN (New England Revolution) |
| 6 | +1 | Cuauhtémoc BLANCO (Chicago Fire, 3p) |
| Robbie ROGERS (Columbus Crew) | ||
| Chris ROLFE (Chicago Fire) | ||
| Guillermo BARROS SCHELOTTO (Columbus Crew, 4p) | ||
| Arturo ÁLVAREZ (San Jose Earthquakes) | ||
| Adam CRISTMAN (New England Revolution) | ||
| Dave VAN DEN BERGH (New York Red Bulls) | ||
| Omar CUMMINGS (Colorado Rapids) | ||
| Darren HUCKERBY (San Jose Earthquakes) | ||
| +1 | Javier MORALES (Real Salt Lake) |
| Thursday, 2 October 2008 | |||||
| FC Dallas | 1-1 | San Jose Earthquakes | |||
| 89(p) | Cooper | 58 | Johnson | ||
| Saturday, 4 October 2008 | |||||
| D.C. United | 0-3 | Chivas USA | |||
| 35 | Eskandarian | ||||
| 56 | Victorine | ||||
| 68 | Dejair | ||||
| Colorado Rapids | 1-3 | Houston Dynamo | |||
| 7 | Casey | 2 | Ching | ||
| 9 | Ching | ||||
| 19 | Clark | ||||
| New York Red Bulls | 1-3 | Toronto FC | |||
| 49 | Richards | 27 | Barrett | ||
| 65 | Barrett | ||||
| 86 | Ibrahim | ||||
| Columbus Crew | 1-0 | LA Galaxy | |||
| 43 | Moreno | ||||
| New England Revolution | 2-2 | Real Salt Lake | |||
| 77 | Ralston | 13 | Morales | ||
| 79 | Twellman | 73 | Williams | ||
| Sunday, 5 October 2008 | |||||
| Kansas City Wizards | 1-1 | Chicago Fire | |||
| 48 | Harrington | 46(p) | Blanco | ||
