Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
| 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 161 | 435 | 2.70 | 83 | 51.55% | 42 | 26.09% | 36 | 22.36% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Columbus Crew | 23 | 13 | 4 | 6 | 40 | 29 | +11 | 43 | WWWW | 12 | 8 | 2 | 2 | 25 | 14 | 11 | 5 | 2 | 4 | 15 | 15 | ||
| 2 | 1 | Chicago Fire | 23 | 11 | 5 | 7 | 30 | 18 | +12 | 38 | WLWL | 11 | 5 | 2 | 4 | 12 | 8 | 12 | 6 | 3 | 3 | 18 | 10 | |
| 3 | 1 | New England Revolution | 23 | 11 | 5 | 7 | 31 | 33 | -2 | 38 | LXXW | 11 | 5 | 3 | 3 | 17 | 14 | 12 | 6 | 2 | 4 | 14 | 19 | |
| 4 | D.C. United | 23 | 10 | 2 | 11 | 37 | 36 | +1 | 32 | LOWL | 12 | 8 | 1 | 3 | 28 | 13 | 11 | 2 | 1 | 8 | 9 | 23 | ||
| 5 | New York Red Bulls | 23 | 8 | 8 | 7 | 28 | 29 | -1 | 32 | LOWW | 11 | 7 | 3 | 1 | 20 | 10 | 12 | 1 | 5 | 6 | 8 | 19 | ||
| 6 | Toronto FC | 23 | 7 | 5 | 11 | 24 | 32 | -8 | 26 | LLXL | 12 | 5 | 5 | 2 | 12 | 8 | 11 | 2 | 0 | 9 | 12 | 24 | ||
| 7 | Kansas City Wizards | 23 | 6 | 8 | 9 | 24 | 33 | -9 | 26 | LLXL | 10 | 5 | 3 | 2 | 13 | 12 | 13 | 1 | 5 | 7 | 11 | 21 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Houston Dynamo | 23 | 10 | 8 | 5 | 34 | 27 | +7 | 38 | WWLW | 12 | 8 | 3 | 1 | 25 | 13 | 11 | 2 | 5 | 4 | 9 | 14 | ||
| 2 | Real Salt Lake | 23 | 8 | 7 | 8 | 29 | 29 | +0 | 31 | XWLL | 12 | 7 | 5 | 0 | 20 | 7 | 11 | 1 | 2 | 8 | 9 | 22 | ||
| 3 | Chivas USA | 23 | 8 | 6 | 9 | 31 | 33 | -2 | 30 | WWOL | 12 | 6 | 3 | 3 | 17 | 11 | 11 | 2 | 3 | 6 | 14 | 22 | ||
| 4 | 2 | San Jose Earthquakes | 23 | 7 | 7 | 9 | 23 | 27 | -4 | 28 | WWOW | 11 | 5 | 3 | 3 | 17 | 14 | 12 | 2 | 4 | 6 | 6 | 13 | |
| 5 | 2 | Colorado Rapids | 23 | 8 | 3 | 12 | 30 | 32 | -2 | 27 | WLLW | 11 | 6 | 1 | 4 | 17 | 9 | 12 | 2 | 2 | 8 | 13 | 23 | |
| 6 | 2 | FC Dallas | 23 | 6 | 8 | 9 | 30 | 30 | +0 | 26 | LLXL | 12 | 4 | 4 | 4 | 17 | 16 | 11 | 2 | 4 | 5 | 13 | 14 | |
| 7 | 2 | LA Galaxy | 23 | 6 | 8 | 9 | 44 | 47 | -3 | 26 | XXLX | 12 | 4 | 4 | 4 | 25 | 21 | 11 | 2 | 4 | 5 | 19 | 26 | |
| 16 | Landon DONOVAN (LA Galaxy, 3p) | |
| 13 | Kenny COOPER (FC Dallas, 2p) | |
| +1 | Edson BUDDLE (LA Galaxy) | |
| 11 | Luciano EMILIO (D.C. United) | |
| 9 | Brian CHING (Houston Dynamo) | |
| Jaime MORENO (D.C. United, 4p) | ||
| 8 | Alejandro MORENO (Columbus Crew) | |
| Juan Pablo ÁNGEL (New York Red Bulls) | ||
| 7 | Chad BARRETT (Toronto FC) | |
| 6 | +1 | Guillermo BARROS SCHELOTTO (Columbus Crew, 4p) |
| +1 | Arturo ÁLVAREZ (San Jose Earthquakes) | |
| Adam CRISTMAN (New England Revolution) | ||
| Steve RALSTON (New England Revolution, 1p) | ||
| 5 | Robbie ROGERS (Columbus Crew) | |
| Jimmy CONRAD (Kansas City Wizards) | ||
| +1 | Ante RAZOV (Chivas USA) | |
| John THORRINGTON (Chicago Fire) | ||
| Taylor TWELLMAN (New England Revolution) | ||
| Edgar ESPÍNDOLA (Real Salt Lake) | ||
| Dwayne DE ROSARIO (Houston Dynamo, 1p) | ||
| Danny DICHIO (Toronto FC) | ||
| Dave VAN DEN BERGH (New York Red Bulls) | ||
| Sacha KLJESTAN (Chivas USA) | ||
| Robbie FINDLEY (Real Salt Lake) | ||
| David BECKHAM (LA Galaxy) | ||
| Dominic ODURO (FC Dallas) | ||
| Jeff CUNNINGHAM (FC Dallas) | ||
| Conor CASEY (Colorado Rapids) |
| Thursday, 4 September 2008 | |||||
| FC Dallas | 0-1 | Colorado Rapids | |||
| 60 | Petke | ||||
| Saturday, 6 September 2008 | |||||
| San Jose Earthquakes | 2-1 | D.C. United | |||
| 18 | Álvarez | 76 | Quaranta | ||
| 62 | Huckerby | ||||
| LA Galaxy | 2-2 | Real Salt Lake | |||
| 9 | Jordan | 21 | Movsisyan | ||
| 69 | Buddle | 52 | Johnson | ||
| Chicago Fire | 1-0 | New York Red Bulls | |||
| 36 | King | ||||
| Toronto FC | 1-3 | Chivas USA | |||
| 30 | Rosenlund | 41 | Paladini | ||
| 58 | Bornstein | ||||
| 90 | Razov | ||||
| Columbus Crew | 4-0 | New England Revolution | |||
| 40 | Barros Schelotto | ||||
| 45 | Iro | ||||
| 67 | Garey | ||||
| 90 | Garey | ||||
| Sunday, 7 September 2008 | |||||
| Houston Dynamo | 3-1 | Kansas City Wizards | |||
| 28 | Davis | 87 | Arnaud | ||
| 54 | Jaqua | ||||
| 67 | Jaqua | ||||
