Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 |
| 16 | 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 181 | 502 | 2.77 | 93 | 51.38% | 47 | 25.97% | 41 | 22.65% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Columbus Crew | 26 | 15 | 5 | 6 | 45 | 31 | +14 | 50 | WWXW | 13 | 9 | 2 | 2 | 28 | 15 | 13 | 6 | 3 | 4 | 17 | 16 | ||
| 2 | New England Revolution | 26 | 12 | 6 | 8 | 36 | 35 | +1 | 42 | LXWL | 13 | 6 | 3 | 4 | 21 | 15 | 13 | 6 | 3 | 4 | 15 | 20 | ||
| 3 | Chicago Fire | 26 | 12 | 5 | 9 | 34 | 25 | +9 | 41 | WLLW | 13 | 6 | 2 | 5 | 16 | 13 | 13 | 6 | 3 | 4 | 18 | 12 | ||
| 4 | New York Red Bulls | 26 | 9 | 8 | 9 | 35 | 38 | -3 | 35 | LLWL | 13 | 8 | 3 | 2 | 26 | 16 | 13 | 1 | 5 | 7 | 9 | 22 | ||
| 5 | D.C. United | 26 | 10 | 3 | 13 | 41 | 46 | -5 | 33 | LLXL | 13 | 8 | 2 | 3 | 30 | 15 | 13 | 2 | 1 | 10 | 11 | 31 | ||
| 6 | Kansas City Wizards | 26 | 8 | 8 | 10 | 29 | 35 | -6 | 32 | LWWL | 12 | 7 | 3 | 2 | 17 | 12 | 14 | 1 | 5 | 8 | 12 | 23 | ||
| 7 | Toronto FC | 26 | 7 | 7 | 12 | 26 | 36 | -10 | 28 | XLXL | 14 | 5 | 7 | 2 | 14 | 10 | 12 | 2 | 0 | 10 | 12 | 26 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Houston Dynamo | 25 | 10 | 10 | 5 | 36 | 29 | +7 | 40 | XXWW | 12 | 8 | 3 | 1 | 25 | 13 | 13 | 2 | 7 | 4 | 11 | 16 | ||
| 2 | Chivas USA | 26 | 10 | 6 | 10 | 34 | 38 | -4 | 36 | WWLW | 13 | 7 | 3 | 3 | 19 | 12 | 13 | 3 | 3 | 7 | 15 | 26 | ||
| 3 | Colorado Rapids | 26 | 10 | 4 | 12 | 38 | 37 | +1 | 34 | WXWW | 13 | 7 | 2 | 4 | 20 | 10 | 13 | 3 | 2 | 8 | 18 | 27 | ||
| 4 | Real Salt Lake | 26 | 9 | 7 | 10 | 33 | 34 | -1 | 34 | WLLX | 13 | 7 | 5 | 1 | 20 | 8 | 13 | 2 | 2 | 9 | 13 | 26 | ||
| 5 | FC Dallas | 26 | 8 | 9 | 9 | 39 | 33 | +6 | 33 | WWXL | 13 | 5 | 4 | 4 | 20 | 16 | 13 | 3 | 5 | 5 | 19 | 17 | ||
| 6 | LA Galaxy | 26 | 7 | 8 | 11 | 50 | 54 | -4 | 29 | LWLX | 13 | 5 | 4 | 4 | 30 | 23 | 13 | 2 | 4 | 7 | 20 | 31 | ||
| 7 | San Jose Earthquakes | 25 | 7 | 8 | 10 | 26 | 31 | -5 | 29 | LXWW | 13 | 5 | 4 | 4 | 20 | 18 | 12 | 2 | 4 | 6 | 6 | 13 | ||
| 19 | Landon DONOVAN (LA Galaxy, 3p) | |
| 15 | +1 | Kenny COOPER (FC Dallas, 2p) |
| 13 | Edson BUDDLE (LA Galaxy) | |
| 11 | +1 | Juan Pablo ÁNGEL (New York Red Bulls, 1p) |
| Luciano EMILIO (D.C. United) | ||
| 10 | Brian CHING (Houston Dynamo) | |
| Jaime MORENO (D.C. United, 4p) | ||
| 8 | Alejandro MORENO (Columbus Crew) | |
| +1 | Jeff CUNNINGHAM (FC Dallas) | |
| +3 | Conor CASEY (Colorado Rapids, 1p) | |
| 7 | Chad BARRETT (Toronto FC) | |
| Steve RALSTON (New England Revolution, 1p) | ||
| 6 | Robbie ROGERS (Columbus Crew) | |
| +2 | Chris ROLFE (Chicago Fire) | |
| Guillermo BARROS SCHELOTTO (Columbus Crew, 4p) | ||
| Arturo ÁLVAREZ (San Jose Earthquakes) | ||
| Taylor TWELLMAN (New England Revolution) | ||
| Adam CRISTMAN (New England Revolution) | ||
| Dave VAN DEN BERGH (New York Red Bulls) | ||
| +1 | Omar CUMMINGS (Colorado Rapids) | |
| +2 | Darren HUCKERBY (San Jose Earthquakes) |
| Thursday, 25 September 2008 | |||||
| Chicago Fire | 3-1 | LA Galaxy | |||
| 13 | Rolfe | 35 | Lewis | ||
| 57 | Blanco | ||||
| 59 | Rolfe | ||||
| Saturday, 27 September 2008 | |||||
| Toronto FC | 1-1 | Houston Dynamo | |||
| 73 | Wynne | 23(og) | Freeman | ||
| New England Revolution | 0-1 | Columbus Crew | |||
| 35 | Marshall | ||||
| Chivas USA | 2-1 | Kansas City Wizards | |||
| 26 | Eskandarian | 70 | Wolff | ||
| 46 | Victorine | ||||
| New York Red Bulls | 4-5 | Colorado Rapids | |||
| 5 | Magee | 3 | Cummings | ||
| 34(p) | Ángel | 11 | Casey | ||
| 40 | Richards | 43 | Petke | ||
| 74 | Mbuta | 45(p) | Casey | ||
| 90 | Casey | ||||
| San Jose Earthquakes | 2-3 | Real Salt Lake | |||
| 23 | Huckerby | 3 | Movsisyan | ||
| 47 | Huckerby | 49 | Movsisyan | ||
| 59 | Morales | ||||
| Sunday, 28 September 2008 | |||||
| FC Dallas | 3-0 | D.C. United | |||
| 9 | André Rocha | ||||
| 56 | Cunningham | ||||
| 90 | Cooper | ||||
