Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 |
| 17 | 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 183 | 578 | 3.15 | 101 | 55.19% | 33 | 18.03% | 49 | 26.78% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Metrostars | 31 | 17 | 3 | 11 | 61 | 52 | +9 | 54 | WLWO | 16 | 9 | 3 | 4 | 32 | 24 | 15 | 8 | 0 | 7 | 29 | 28 | ||
| 2 | New England Revolution | 30 | 12 | 6 | 12 | 43 | 45 | -2 | 42 | LWWW | 14 | 8 | 3 | 3 | 23 | 16 | 16 | 4 | 3 | 9 | 20 | 29 | ||
| 3 | Miami Fusion | 31 | 11 | 5 | 15 | 48 | 54 | -6 | 38 | LWLL | 16 | 8 | 3 | 5 | 31 | 26 | 15 | 3 | 2 | 10 | 17 | 28 | ||
| 4 | D.C. United | 31 | 8 | 6 | 17 | 42 | 57 | -15 | 30 | WLWL | 15 | 6 | 3 | 6 | 23 | 25 | 16 | 2 | 3 | 11 | 19 | 32 | ||
| Central | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | 1 | Chicago Fire | 30 | 15 | 6 | 9 | 61 | 48 | +13 | 51 | WWXW | 15 | 12 | 1 | 2 | 37 | 17 | 15 | 3 | 5 | 7 | 24 | 31 | |
| 2 | 1 | Tampa Bay Mutiny | 31 | 16 | 3 | 12 | 60 | 48 | +12 | 51 | LWXL | 15 | 10 | 1 | 4 | 36 | 21 | 16 | 6 | 2 | 8 | 24 | 27 | |
| 3 | Dallas Burn | 30 | 12 | 4 | 14 | 51 | 53 | -2 | 40 | LLWW | 15 | 10 | 2 | 3 | 35 | 21 | 15 | 2 | 2 | 11 | 16 | 32 | ||
| 4 | Columbus Crew | 30 | 11 | 5 | 14 | 45 | 52 | -7 | 38 | LLLW | 15 | 7 | 3 | 5 | 27 | 22 | 15 | 4 | 2 | 9 | 18 | 30 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Kansas City Wizards | 30 | 15 | 8 | 7 | 44 | 27 | +17 | 53 | WXOL | 16 | 11 | 1 | 4 | 27 | 14 | 14 | 4 | 7 | 3 | 17 | 13 | ||
| 2 | LA Galaxy | 30 | 14 | 8 | 8 | 47 | 35 | +12 | 50 | WWLW | 15 | 8 | 5 | 2 | 20 | 14 | 15 | 6 | 3 | 6 | 27 | 21 | ||
| 3 | Colorado Rapids | 31 | 12 | 4 | 15 | 42 | 59 | -17 | 40 | LWXL | 15 | 7 | 3 | 5 | 18 | 21 | 16 | 5 | 1 | 10 | 24 | 38 | ||
| 4 | San Jose Clash | 31 | 7 | 8 | 16 | 34 | 48 | -14 | 29 | WLLW | 16 | 5 | 5 | 6 | 26 | 22 | 15 | 2 | 3 | 10 | 8 | 26 | ||
| 26 | Mamadou DIALLO (Tampa Bay Mutiny, 1p) | |
| 16 | +1 | Adolfo VALENCIA (Metrostars, 4p) |
| Ante RAZOV (Chicago Fire, 2p) | ||
| Clint MATHIS (Metrostars, 1p) | ||
| 15 | Wolde HARRIS (New England Revolution) | |
| Dante WASHINGTON (Columbus Crew) | ||
| 14 | Ariel GRAZIANI (Dallas Burn) | |
| 13 | +5 | Diego SERNA (Miami Fusion, 1p) |
| 12 | Jaime MORENO (D.C. United, 1p) | |
| 11 | Jason KREIS (Dallas Burn) | |
| 10 | Junior AGOGO (Colorado Rapids, 1p) | |
| +1 | Alex COMAS (Metrostars, 2p) | |
| +1 | Miklos MOLNAR (Kansas City Wizards) | |
| +2 | Dmytro KOVALENKO (Chicago Fire) | |
| 9 | Raul ARCE (D.C. United) | |
| 8 | Manny LAGOS (Tampa Bay Mutiny) | |
| Chris HENDERSON (Kansas City Wizards) | ||
| Roy LASSITER (Miami Fusion, 1p) | ||
| Abdul CONTEH (San Jose Clash) | ||
| Hristo STOICHKOV (Chicago Fire, 2p) | ||
| Imad BABA (New England Revolution, 2p) |
| Friday, 1 September 2000 | |||||
| San Jose Clash | 3-0 | Columbus Crew | |||
| 2 | Doyle | ||||
| 4 | Russell | ||||
| 90 | Krakowiak | ||||
| Saturday, 2 September 2000 | |||||
| Kansas City Wizards | 1-0 | Tampa Bay Mutiny | |||
| 10 | Molnar | ||||
| Miami Fusion | 4-1 | Metrostars | |||
| 43(p) | Serna | 45(p) | Comas | ||
| 44 | Serna | ||||
| 72 | Serna | ||||
| 81 | Serna | ||||
| Sunday, 3 September 2000 | |||||
| D.C. United | 2-0 | New England Revolution | |||
| 55 | Marino | ||||
| 61 | Marino | ||||
| Chicago Fire | 2-1 | Colorado Rapids | |||
| 26 | Kovalenko | 7 | Paule | ||
| 32 | Kovalenko | ||||
| Tuesday, 5 September 2000 | |||||
| Metrostars | 2-1 | Miami Fusion | |||
| 10 | Petke | 83 | Serna | ||
| 82(p) | Valencia | ||||
