Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 270 | 721 | 2.67 | 146 | 54.07% | 58 | 21.48% | 66 | 24.44% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Sporting Kansas City | 28 | 15 | 6 | 7 | 35 | 25 | +10 | 51 | XWXW | 15 | 8 | 4 | 3 | 18 | 11 | 13 | 7 | 2 | 4 | 17 | 14 | ||
| 2 | 1 | Chicago Fire | 28 | 15 | 5 | 8 | 40 | 33 | +7 | 50 | WWWL | 14 | 10 | 2 | 2 | 23 | 13 | 14 | 5 | 3 | 6 | 17 | 20 | |
| 3 | 1 | New York Red Bulls | 28 | 14 | 7 | 7 | 49 | 40 | +9 | 49 | WXXW | 13 | 10 | 3 | 0 | 30 | 13 | 15 | 4 | 4 | 7 | 19 | 27 | |
| 4 | Houston Dynamo | 29 | 12 | 10 | 7 | 41 | 34 | +7 | 46 | XWLX | 14 | 9 | 5 | 0 | 25 | 10 | 15 | 3 | 5 | 7 | 16 | 24 | ||
| 5 | 1 | D.C. United | 28 | 13 | 5 | 10 | 45 | 39 | +6 | 44 | WLXL | 15 | 10 | 4 | 1 | 33 | 15 | 13 | 3 | 1 | 9 | 12 | 24 | |
| 6 | 1 | Columbus Crew | 28 | 12 | 6 | 10 | 34 | 35 | -1 | 42 | LLWW | 13 | 8 | 2 | 3 | 21 | 17 | 15 | 4 | 4 | 7 | 13 | 18 | |
| 7 | Montréal Impact | 30 | 12 | 3 | 15 | 44 | 49 | -5 | 39 | LLWW | 15 | 10 | 2 | 3 | 31 | 18 | 15 | 2 | 1 | 12 | 13 | 31 | ||
| 8 | New England Revolution | 29 | 7 | 7 | 15 | 36 | 40 | -4 | 28 | LWOX | 15 | 6 | 5 | 4 | 21 | 14 | 14 | 1 | 2 | 11 | 15 | 26 | ||
| 9 | Philadelphia Union | 26 | 7 | 6 | 13 | 26 | 31 | -5 | 27 | XOLO | 13 | 5 | 2 | 6 | 18 | 15 | 13 | 2 | 4 | 7 | 8 | 16 | ||
| 10 | Toronto FC | 29 | 5 | 7 | 17 | 32 | 51 | -19 | 22 | XLLX | 15 | 3 | 4 | 8 | 15 | 24 | 14 | 2 | 3 | 9 | 17 | 27 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | San Jose Earthquakes | 28 | 17 | 5 | 6 | 58 | 33 | +25 | 56 | WWWL | 14 | 10 | 3 | 1 | 36 | 15 | 14 | 7 | 2 | 5 | 22 | 18 | ||
| 2 | 1 | Seattle Sounders | 28 | 13 | 9 | 6 | 44 | 29 | +15 | 48 | XWXW | 13 | 9 | 1 | 3 | 20 | 8 | 15 | 4 | 8 | 3 | 24 | 21 | |
| 3 | 1 | LA Galaxy | 29 | 14 | 4 | 11 | 50 | 40 | +10 | 46 | WWWX | 14 | 8 | 1 | 5 | 25 | 16 | 15 | 6 | 3 | 6 | 25 | 24 | |
| 4 | 2 | Real Salt Lake | 29 | 14 | 4 | 11 | 38 | 33 | +5 | 46 | LWOL | 15 | 10 | 1 | 4 | 25 | 14 | 14 | 4 | 3 | 7 | 13 | 19 | |
| 5 | Vancouver Whitecaps | 29 | 10 | 7 | 12 | 29 | 38 | -9 | 37 | LLLL | 13 | 7 | 4 | 2 | 19 | 14 | 16 | 3 | 3 | 10 | 10 | 24 | ||
| 6 | FC Dallas | 30 | 9 | 9 | 12 | 35 | 38 | -3 | 36 | WXLW | 16 | 6 | 7 | 3 | 19 | 14 | 14 | 3 | 2 | 9 | 16 | 24 | ||
| 7 | Colorado Rapids | 29 | 9 | 2 | 18 | 36 | 43 | -7 | 29 | LWLL | 14 | 7 | 2 | 5 | 25 | 14 | 15 | 2 | 0 | 13 | 11 | 29 | ||
| 8 | 1 | Portland Timbers | 28 | 7 | 7 | 14 | 28 | 47 | -19 | 28 | XLWW | 15 | 7 | 4 | 4 | 22 | 19 | 13 | 0 | 3 | 10 | 6 | 28 | |
| 9 | 1 | Chivas USA | 27 | 7 | 7 | 13 | 21 | 43 | -22 | 28 | LLLX | 14 | 3 | 2 | 9 | 8 | 23 | 13 | 4 | 5 | 4 | 13 | 20 | |
| 19 | +1 | Chris WONDOLOWSKI (San Jose Earthquakes) |
| 14 | Kenny COOPER (New York Red Bulls) | |
| Álvaro SABORIO (Real Salt Lake) | ||
| 13 | +2 | Eddie JOHNSON (Seattle Sounders) |
| +2 | Thierry HENRY (New York Red Bulls) | |
| 12 | +1 | Robbie KEANE (LA Galaxy) |
| +1 | Fredy MONTERO (Seattle Sounders) | |
| +1 | Alan GORDON (San Jose Earthquakes) | |
| 11 | +1 | Chris PONTIUS (D.C. United) |
| Will BRUIN (Houston Dynamo) | ||
| Saër SÈNE (New England Revolution) | ||
| 10 | Kei KAMARA (Sporting Kansas City) | |
| 9 | Landon DONOVAN (LA Galaxy) | |
| Danny KOEVERMANS (Toronto FC) | ||
| Patrice BERNIER (Montréal Impact) | ||
| 8 | Steven LENHART (San Jose Earthquakes) | |
| 7 | Simon DAWKINS (San Jose Earthquakes) | |
| +1 | Brad DAVIS (Houston Dynamo) | |
| Eddie GAVEN (Columbus Crew) | ||
| Jaime CASTRILLÓN (Colorado Rapids) | ||
| Dwayne DE ROSARIO (D.C. United) | ||
| Darren MATTOCKS (Vancouver Whitecaps) | ||
| Kris BOYD (Portland Timbers) | ||
| David BECKHAM (LA Galaxy) | ||
| MAICON CARIOCA (D.C. United) |
| Thursday, 6 September 2012 | |||||
| Houston Dynamo | 1-0 | Real Salt Lake | |||
| 90 | Clark | ||||
| Saturday, 8 September 2012 | |||||
| Seattle Sounders | 2-1 | Chivas USA | |||
| 28 | Johnson | 8 | Labrocca | ||
| 89 | Johnson | ||||
| Wednesday, 12 September 2012 | |||||
| Toronto FC | 1-2 | Chicago Fire | |||
| 79 | Hassli | 13 | Fernández | ||
| 42 | Rolfe | ||||
| Friday, 14 September 2012 | |||||
| Sporting Kansas City | 1-1 | Houston Dynamo | |||
| 90 | Sapong | 58 | Davis | ||
| LA Galaxy | 2-0 | Colorado Rapids | |||
| 15 | Keane | ||||
| 58 | Wilhelmsson | ||||
| Saturday, 15 September 2012 | |||||
| New York Red Bulls | 3-1 | Columbus Crew | |||
| 9 | Henry | 3 | Mirosevic | ||
| 79 | McCarty | ||||
| 90 | Henry | ||||
| Chicago Fire | 3-1 | Montréal Impact | |||
| 34 | Macdonald | 20 | Di Vaio | ||
| 61 | Alex Lima | ||||
| 80 | Fernández | ||||
| Portland Timbers | 1-1 | Seattle Sounders | |||
| 78 | Wallace | 57 | Montero | ||
| D.C. United | 2-1 | New England Revolution | |||
| 32 | Pontius | 29 | Rowe | ||
| 63 | Neal | ||||
| FC Dallas | 1-0 | Vancouver Whitecaps | |||
| 90 | De Guzman | ||||
| Chivas USA | 0-2 | San Jose Earthquakes | |||
| 40 | Wondolowski | ||||
| 49 | Gordon | ||||
| Toronto FC | 1-1 | Philadelphia Union | |||
| 58 | Hassli | 85 | Williams | ||
