Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 258 | 692 | 2.68 | 139 | 53.88% | 55 | 21.32% | 64 | 24.81% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Sporting Kansas City | 27 | 15 | 5 | 7 | 34 | 24 | +10 | 50 | WXWW | 14 | 8 | 3 | 3 | 17 | 10 | 13 | 7 | 2 | 4 | 17 | 14 | ||
| 2 | New York Red Bulls | 27 | 13 | 7 | 7 | 46 | 39 | +7 | 46 | XXWW | 12 | 9 | 3 | 0 | 27 | 12 | 15 | 4 | 4 | 7 | 19 | 27 | ||
| 3 | 2 | Chicago Fire | 26 | 13 | 5 | 8 | 35 | 31 | +4 | 44 | WLWW | 13 | 9 | 2 | 2 | 20 | 12 | 13 | 4 | 3 | 6 | 15 | 19 | |
| 4 | 1 | Houston Dynamo | 27 | 11 | 9 | 7 | 39 | 33 | +6 | 42 | LXXL | 13 | 8 | 5 | 0 | 24 | 10 | 14 | 3 | 4 | 7 | 15 | 23 | |
| 5 | 1 | Columbus Crew | 27 | 12 | 6 | 9 | 33 | 32 | +1 | 42 | LWWW | 13 | 8 | 2 | 3 | 21 | 17 | 14 | 4 | 4 | 6 | 12 | 15 | |
| 6 | 2 | D.C. United | 27 | 12 | 5 | 10 | 43 | 38 | +5 | 41 | LXLW | 14 | 9 | 4 | 1 | 31 | 14 | 13 | 3 | 1 | 9 | 12 | 24 | |
| 7 | Montréal Impact | 29 | 12 | 3 | 14 | 43 | 46 | -3 | 39 | LWWW | 15 | 10 | 2 | 3 | 31 | 18 | 14 | 2 | 1 | 11 | 12 | 28 | ||
| 8 | 1 | New England Revolution | 28 | 7 | 7 | 14 | 35 | 38 | -3 | 28 | WOXL | 15 | 6 | 5 | 4 | 21 | 14 | 13 | 1 | 2 | 10 | 14 | 24 | |
| 9 | 1 | Philadelphia Union | 25 | 7 | 5 | 13 | 25 | 30 | -5 | 26 | OLOX | 13 | 5 | 2 | 6 | 18 | 15 | 12 | 2 | 3 | 7 | 7 | 15 | |
| 10 | Toronto FC | 27 | 5 | 6 | 16 | 30 | 48 | -18 | 21 | LXLL | 13 | 3 | 3 | 7 | 13 | 21 | 14 | 2 | 3 | 9 | 17 | 27 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | San Jose Earthquakes | 27 | 16 | 5 | 6 | 56 | 33 | +23 | 53 | WWLW | 14 | 10 | 3 | 1 | 36 | 15 | 13 | 6 | 2 | 5 | 20 | 18 | ||
| 2 | 1 | Real Salt Lake | 28 | 14 | 4 | 10 | 38 | 32 | +6 | 46 | WOLL | 15 | 10 | 1 | 4 | 25 | 14 | 13 | 4 | 3 | 6 | 13 | 18 | |
| 3 | 1 | Seattle Sounders | 26 | 12 | 8 | 6 | 41 | 27 | +14 | 44 | XWWL | 12 | 8 | 1 | 3 | 18 | 7 | 14 | 4 | 7 | 3 | 23 | 20 | |
| 4 | LA Galaxy | 28 | 13 | 4 | 11 | 48 | 40 | +8 | 43 | WWXW | 13 | 7 | 1 | 5 | 23 | 16 | 15 | 6 | 3 | 6 | 25 | 24 | ||
| 5 | Vancouver Whitecaps | 28 | 10 | 7 | 11 | 29 | 37 | -8 | 37 | LLLL | 13 | 7 | 4 | 2 | 19 | 14 | 15 | 3 | 3 | 9 | 10 | 23 | ||
| 6 | FC Dallas | 29 | 8 | 9 | 12 | 34 | 38 | -4 | 33 | XLWW | 15 | 5 | 7 | 3 | 18 | 14 | 14 | 3 | 2 | 9 | 16 | 24 | ||
| 7 | 1 | Colorado Rapids | 28 | 9 | 2 | 17 | 36 | 41 | -5 | 29 | WLLX | 14 | 7 | 2 | 5 | 25 | 14 | 14 | 2 | 0 | 12 | 11 | 27 | |
| 8 | 1 | Chivas USA | 25 | 7 | 7 | 11 | 20 | 39 | -19 | 28 | LXLX | 13 | 3 | 2 | 8 | 8 | 21 | 12 | 4 | 5 | 3 | 12 | 18 | |
| 9 | Portland Timbers | 27 | 7 | 6 | 14 | 27 | 46 | -19 | 27 | LWWL | 14 | 7 | 3 | 4 | 21 | 18 | 13 | 0 | 3 | 10 | 6 | 28 | ||
| 18 | Chris WONDOLOWSKI (San Jose Earthquakes) | |
| 14 | Kenny COOPER (New York Red Bulls) | |
| Álvaro SABORIO (Real Salt Lake) | ||
| 11 | Eddie JOHNSON (Seattle Sounders) | |
| Robbie KEANE (LA Galaxy) | ||
| Fredy MONTERO (Seattle Sounders) | ||
| Will BRUIN (Houston Dynamo) | ||
| Alan GORDON (San Jose Earthquakes) | ||
| Saër SÈNE (New England Revolution) | ||
| Thierry HENRY (New York Red Bulls) | ||
| 10 | Kei KAMARA (Sporting Kansas City) | |
| Chris PONTIUS (D.C. United) | ||
| 9 | Landon DONOVAN (LA Galaxy) | |
| Danny KOEVERMANS (Toronto FC) | ||
| Patrice BERNIER (Montréal Impact) | ||
| 8 | Steven LENHART (San Jose Earthquakes) | |
| 7 | +1 | Simon DAWKINS (San Jose Earthquakes) |
| Eddie GAVEN (Columbus Crew) | ||
| +1 | Jaime CASTRILLÓN (Colorado Rapids) | |
| Dwayne DE ROSARIO (D.C. United) | ||
| Darren MATTOCKS (Vancouver Whitecaps) | ||
| Kris BOYD (Portland Timbers) | ||
| +1 | David BECKHAM (LA Galaxy) | |
| MAICON CARIOCA (D.C. United) |
| Friday, 31 August 2012 | |||||
| Portland Timbers | 1-0 | Colorado Rapids | |||
| 45 | Dike | ||||
| Saturday, 1 September 2012 | |||||
| Columbus Crew | 2-1 | Montréal Impact | |||
| 80 | Marshall | 73 | Di Vaio | ||
| 90 | Rentería | ||||
| Sporting Kansas City | 2-1 | Toronto FC | |||
| 60 | Paulo Nagamura | 44 | Johnson | ||
| 88 | Oriol | ||||
| New England Revolution | 0-0 | Philadelphia Union | |||
| LA Galaxy | 2-0 | Vancouver Whitecaps | |||
| 41 | Juninho | ||||
| 79 | Beckham | ||||
| Real Salt Lake | 1-0 | D.C. United | |||
| 49 | Johnson | ||||
| Sunday, 2 September 2012 | |||||
| Chicago Fire | 3-1 | Houston Dynamo | |||
| 1 | Nyarko | 90 | Ching | ||
| 19 | Paladini | ||||
| 90 | Alex Lima | ||||
| FC Dallas | 1-1 | Seattle Sounders | |||
| 32 | Jackson | 20 | Rosales | ||
| San Jose Earthquakes | 4-0 | Chivas USA | |||
| 11 | Bernárdez | ||||
| 39 | Dawkins | ||||
| 71 | Corrales | ||||
| 81 | Corrales | ||||
| Wednesday, 5 September 2012 | |||||
| Colorado Rapids | 3-0 | Portland Timbers | |||
| 6 | Akpan | ||||
| 27 | Cascio | ||||
| 86 | Castrillón | ||||
| New England Revolution | 2-0 | Columbus Crew | |||
| 53 | Imbongo | ||||
| 74(og) | Marshall | ||||
