 Anagennisi Plagias |
| 13-Feb-2022 | Gamma Ethniki (15) | Apollon Paralimniou | 3-0 | Anagennisi Plagias |
| 20-Feb-2022 | Gamma Ethniki (16) | Anagennisi Plagias | 0-2 | Ethnikos Sochou |
| 27-Feb-2022 | Gamma Ethniki (17) | Orfeas Xanthis | 2-1 | Anagennisi Plagias |
| 09-Mar-2022 | Gamma Ethniki (18) | Doxa Drama | 5-3 | Anagennisi Plagias |
| 13-Mar-2022 | Gamma Ethniki (19) | Anagennisi Plagias | 3-0 | Enosi Alexandroupolis |
| 23-Mar-2022 | Gamma Ethniki (20) | Aris Avatou | 3-0 | Anagennisi Plagias |
| 03-Apr-2022 | Gamma Ethniki (21) | Anagennisi Plagias | 0-3 | Pandramaikos |
| 17-Apr-2022 | Gamma Ethniki (22) | Agrotikos Asteras | 2-0 | Anagennisi Plagias |
