Results| Tuesday, 4 August 2009 |
| q1l1 |  Universidad de Chile | 2-1 | Cali |
| 60 | Olivera |
| 47 | Herrera |
| 66(p) | Olivera |
| |
| Wednesday, 5 August 2009 |
| q1l1 | La Equidad | 2-2 | Unión Española |
| 54 | Carreño |
| 3 | Canales |
| 80(og) | Miranda |
| 90 | Canales |
| q1l1 |  Zamora | 0-1 | Emelec |
| |
| 90 | Mendoza |
| Thursday, 6 August 2009 |
| q1l1 |  Alianza Atlético | 0-0 | Anzoátegui* |
| Tuesday, 11 August 2009 |
| q1l1 |  Blooming | 0-3 | River Plate |
| |
| 61 | Puppo |
| Score awarded as 0-3. |
| q1l1 | LDU Quito | 1-0 | Libertad |
| 45 | Reasco |
| |
| Wednesday, 12 August 2009 |
| q1l1 | Cerro Porteño | 2-0 | La Paz FC |
| 20 | Nanni |
| |
| 56 | Brítez |
| |
| q1l1 |  Fluminense | 0-0 | Flamengo |
| Thursday, 13 August 2009 |
| q1l1 | Liverpool | 0-0 | Cienciano |
| q1l1 | Vitória | 2-0 | Coritiba |
| 46 | Uélliton |
| |
| 72 | Jackson |
| |
| Tuesday, 18 August 2009 |
| q1l1 |  Tigre | 2-1 | San Lorenzo |
| 4 | Morel |
| 31 | Rivero |
| 8 | Oviedo |
| |
| Wednesday, 19 August 2009 |
| q1l1 | River Plate | 1-2 | Lanús |
| 68 | Fabbiani |
| 80 | Salvio |
| |
| 90 | Salvio |
| Thursday, 20 August 2009 |
| q1l1 | Boca Juniors | 1-1 | Vélez Sársfield |
| 3 | Mouche |
| 33(og) | Paletta |
| Wednesday, 26 August 2009 |
| q1l1 | Atlético-MG | 1-1 | Goiás |
| 60 | Tchô |
| 83(p) | Felipe |
| Wednesday, 2 September 2009 |
| q1l1 | Athlético-PR | 0-0 | Botafogo |
