 Dimitra Efxeinoupolis |
| 13-Feb-2022 | Gamma Ethniki (15) | Dimitra Efxeinoupolis | 1-2 | Iraklis Larisas |
| 20-Feb-2022 | Gamma Ethniki (16) | Atromitos Palama | 2-0 | Dimitra Efxeinoupolis |
| 02-Mar-2022 | Gamma Ethniki (17) | Dimitra Efxeinoupolis | 5-0 | Atalanti |
| 06-Mar-2022 | Gamma Ethniki (18) | Dimitra Efxeinoupolis | 1-0 | Nea Artakis |
| 13-Mar-2022 | Gamma Ethniki (19) | Ethnikos Neou Keramidiou | 0-1 | Dimitra Efxeinoupolis |
| 20-Mar-2022 | Gamma Ethniki (20) | Dimitra Efxeinoupolis | 3-1 | PO Fikis |
| 27-Mar-2022 | Gamma Ethniki (21) | Elassona | 2-2 | Dimitra Efxeinoupolis |
| 03-Apr-2022 | Gamma Ethniki (22) | Dimitra Efxeinoupolis | 1-1 | Thiseas Agrias |
