Lamar Hunt US Open Cup| ROUND | R2 | R3 | R4 | R5 | QF | SF | F |
| Season archive |
| Tuesday, 19 April 2022 | ||||||
| r3 | FC Dallas | 2-1 | FC Tulsa | |||
| 32(p) | Jara | 42 | Bourgeois | |||
| 55 | Obrian | |||||
| r3 | Houston Dynamo | 2-1 | RGV Toros | |||
| 9(og) | Nodarse | 48(og) | Hadebe | |||
| 90 | Junqua | |||||
| r3 | LA Galaxy | 1-0 | San Diego Loyal | |||
| 28 | Cabral | |||||
| r3 | Chicago Fire | 2-2 | Union Omaha | aet, p4-5 | ||
| 53(p) | Czichos | 68 | Meza | |||
| 115(p) | Czichos | 120 | Touche | |||
| r3 | San Jose Earthquakes | 5-0 | Bay Cities | |||
| 25 | Skahan | |||||
| 37 | Marie | |||||
| 59(p) | Cowell | |||||
| 82 | Tsakiris | |||||
| 88 | Bouda | |||||
| r3 | FC Tucson | 1-2 | California United | |||
| 17 | Calixtro | 71 | ||||
| 90 | ||||||
| r3 | FC Cincinnati | 2-0 | Pittsburgh Riverhounds | aet | ||
| 95(p) | Barreal | |||||
| 99 | Barreal | |||||
| r3 | Miami FC | 0-1 | Inter Miami | |||
| 83 | Campana | |||||
| r3 | Birmingham Legion | 0-2 | Tormenta FC | |||
| 33 | Thorn | |||||
| 45 | Dengler | |||||
| r3 | Detroit City | 2-1 | Columbus Crew | |||
| 64 | Rodriguez | 7(p) | Zardes | |||
| 86(p) | Rodriguez | |||||
| r3 | Flower City Union | 0-3 | D.C. United | |||
| 73 | Kamara | |||||
| 81 | Robertha | |||||
| 86(p) | Kamara | |||||
| Wednesday, 20 April 2022 | ||||||
| r3 | Richmond Kickers | 1-0 | North Carolina Fusion | aet | ||
| 118 | Terzaghi | |||||
| r3 | Rochester New York | 2-2 | FC Motown | aet, p4-3 | ||
| 22 | Pedro Becker | 40 | Duka | |||
| 38 | Inalien | 91 | Fala | |||
| r3 | Real Salt Lake | 0-1 | Northern Colorado | |||
| 70 | Cornwall | |||||
| r3 | Orlando City | 2-1 | Tampa Bay Rowdies | |||
| 52(p) | Alexandre Pato | 65 | Mkosana | |||
| 63 | Júnior Urso | |||||
| r3 | Los Angeles | 5-1 | Orange County SC | |||
| 13 | Musovski | 73 | Torres | |||
| 34 | Arango | |||||
| 45 | Arango | |||||
| 68 | Jennings | |||||
| 71 | Musovski | |||||
| r3 | San Antonio | 2-1 | Austin FC | aet | ||
| 82 | Collier | 47 | Fagúndez | |||
| 96 | Manley | |||||
| r3 | Phoenix Rising | 2-1 | New Mexico United | |||
| 6(og) | Seymore | 65 | Brett | |||
| 81 | Hurst | |||||
| r3 | Sacramento Republic | 2-1 | Central Valley Fuego | |||
| 44 | Casey | 76 | Bustamante | |||
| 90(p) | López | |||||
| r3 | Louisville City | 0-0 | St. Louis CITY SC 2 | aet, p9-8 | ||
| r3 | Atlanta United | 6-0 | Chattanooga FC | |||
| 21 | Hernández | |||||
| 25 | Dwyer | |||||
| 35 | Dwyer | |||||
| 53(p) | Moreno | |||||
| 67 | Luiz Araújo | |||||
| 84 | Lennon | |||||
| r3 | Hartford Athletic | 1-2 | New York Red Bulls | |||
| 51 | McGlynn | 18 | Morgan | |||
| 25 | Long | |||||
| r3 | Forward Madison | 0-2 | Minnesota United | |||
| 51 | Hunou | |||||
| 83 | Kallman | |||||
| r3 | Greenville Triumph | 1-2 | Charlotte FC | aet | ||
| 59 | Keegan | 39 | Ortiz | |||
| 105 | Afful | |||||
| 4 | +1 | Luckymore MKOSANA (Tampa Bay Rowdies) |
| 2 | Jerome KIESEWETTER (New Mexico United, 1p) | |
| +2 | Rafael CZICHOS (Chicago Fire, 2p) | |
| Matt LEWIS (Detroit City) | ||
| +2 | Maxi RODRIGUEZ (Detroit City, 1p) | |
| +1 | Jake KEEGAN (Greenville Triumph) | |
| +2 | Álvaro BARREAL (FC Cincinnati, 1p) | |
| +2 | Ola KAMARA (D.C. United, 1p) | |
| +2 | Danny MUSOVSKI (Los Angeles) | |
| +2 | Cristian ARANGO (Los Angeles) | |
| Duke LACROIX (Sacramento Republic) | ||
| +2 | Dominic DWYER (Atlanta United) | |
| +1 | Rodrigo LÓPEZ (Sacramento Republic, 1p) | |
| Villyan BIJEV (Central Valley Fuego) | ||
| Henrik SAKSHAUG (San Antonio) | ||
| Toby SIMS (Pittsburgh Riverhounds) |
