Leagues Cup| ROUND | R1 |
| Season archive |
| Tuesday, 29 July 2025 | |||||
| r1l1 | Houston Dynamo | - | Tigres | ||
| r1l1 | Columbus Crew | - | Toluca | ||
| r1l1 | CF Montréal | - | León | ||
| r1l1 | Los Angeles | - | Mazatlán | ||
| r1l1 | New York City II | - | Puebla | ||
| r1l1 | San Diego FC | - | Pachuca | ||
| Wednesday, 30 July 2025 | |||||
| r1l1 | Portland Timbers | - | Atlético San Luis | ||
| r1l1 | Real Salt Lake | - | América | ||
| r1l1 | Orlando City | - | UNAM | ||
| r1l1 | Minnesota United | - | Querétaro | ||
| r1l1 | Atlanta United | - | Necaxa | ||
| r1l1 | Inter Miami | - | Atlas | ||
| Thursday, 31 July 2025 | |||||
| r1l1 | Colorado Rapids | - | Santos Laguna | ||
| r1l1 | New York Red Bulls | - | Guadalajara | ||
| r1l1 | LA Galaxy | - | Tijuana | ||
| r1l1 | Seattle Sounders | - | Cruz Azul | ||
| r1l1 | FC Cincinnati | - | Monterrey | ||
| r1l1 | Charlotte FC | - | F.C. Juárez | ||
