Liga Nacional| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | Apertura 2021 |
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 21 | 22 | Clausura 2022 |
| Season archive |
| Sunday, 10 October 2021 | |||||
| 13 | Municipal | - | Santa Lucía Cotzumalguapa | ||
| 13 | Xelajú | - | Antigua | ||
| 13 | Malacateco | - | Achuapa | ||
| 13 | Nueva Concepcion | - | Comunicaciones | ||
| 13 | Iztapa | - | Guastatoya | ||
| 13 | Sololá | - | Cobán Imperial | ||
| Wednesday, 13 October 2021 | |||||
| 8 | Guastatoya | - | Cobán Imperial | ||
