| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 |
| 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 321 | 891 | 2.77 | 161 | 50.16% | 77 | 23.99% | 83 | 25.86% |
| 1999/00 | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Manchester United | 32 | 22 | 7 | 3 | 80 | 39 | +41 | 73 | WWWW | 16 | 12 | 4 | 0 | 49 | 13 | 16 | 10 | 3 | 3 | 31 | 26 | ||
| 2 | 1 | Liverpool | 32 | 18 | 8 | 6 | 49 | 24 | +25 | 62 | WWWW | 17 | 11 | 3 | 3 | 28 | 11 | 15 | 7 | 5 | 3 | 21 | 13 | |
| 3 | 1 | Leeds United | 32 | 19 | 3 | 10 | 49 | 35 | +14 | 60 | LLLW | 16 | 11 | 1 | 4 | 25 | 12 | 16 | 8 | 2 | 6 | 24 | 23 | |
| 4 | 1 | Chelsea | 32 | 16 | 10 | 6 | 43 | 27 | +16 | 58 | WWXO | 16 | 10 | 4 | 2 | 28 | 11 | 16 | 6 | 6 | 4 | 15 | 16 | |
| 5 | 1 | Arsenal | 31 | 17 | 6 | 8 | 56 | 32 | +24 | 57 | WWWL | 16 | 12 | 2 | 2 | 35 | 12 | 15 | 5 | 4 | 6 | 21 | 20 | |
| 6 | Aston Villa | 33 | 14 | 10 | 9 | 37 | 27 | +10 | 52 | WWWL | 16 | 8 | 6 | 2 | 20 | 8 | 17 | 6 | 4 | 7 | 17 | 19 | ||
| 7 | Sunderland | 32 | 14 | 9 | 9 | 52 | 47 | +5 | 51 | WWWX | 17 | 9 | 6 | 2 | 27 | 16 | 15 | 5 | 3 | 7 | 25 | 31 | ||
| 8 | West Ham United | 32 | 13 | 9 | 10 | 44 | 48 | -4 | 48 | WLWO | 16 | 10 | 4 | 2 | 27 | 22 | 16 | 3 | 5 | 8 | 17 | 26 | ||
| 9 | Everton | 33 | 11 | 12 | 10 | 54 | 45 | +9 | 45 | XWLL | 15 | 6 | 8 | 1 | 32 | 18 | 18 | 5 | 4 | 9 | 22 | 27 | ||
| 10 | 1 | Newcastle United | 32 | 12 | 7 | 13 | 53 | 46 | +7 | 43 | LWLW | 15 | 8 | 4 | 3 | 34 | 14 | 17 | 4 | 3 | 10 | 19 | 32 | |
| 11 | 1 | Tottenham Hotspur | 32 | 12 | 7 | 13 | 47 | 40 | +7 | 43 | LLXL | 15 | 8 | 2 | 5 | 32 | 20 | 17 | 4 | 5 | 8 | 15 | 20 | |
| 12 | Middlesbrough | 32 | 12 | 7 | 13 | 38 | 46 | -8 | 43 | LWWX | 17 | 8 | 3 | 6 | 20 | 23 | 15 | 4 | 4 | 7 | 18 | 23 | ||
| 13 | Leicester City | 31 | 12 | 6 | 13 | 44 | 47 | -3 | 42 | XLWL | 17 | 9 | 3 | 5 | 28 | 23 | 14 | 3 | 3 | 8 | 16 | 24 | ||
| 14 | Coventry City | 33 | 10 | 8 | 15 | 41 | 44 | -3 | 38 | LLLW | 17 | 10 | 1 | 6 | 32 | 20 | 16 | 0 | 7 | 9 | 9 | 24 | ||
| 15 | Southampton | 32 | 10 | 7 | 15 | 39 | 55 | -16 | 37 | WLXW | 15 | 6 | 4 | 5 | 20 | 17 | 17 | 4 | 3 | 10 | 19 | 38 | ||
| 16 | 1 | Derby County | 32 | 8 | 8 | 16 | 36 | 46 | -10 | 32 | OWLL | 16 | 5 | 2 | 9 | 19 | 23 | 16 | 3 | 6 | 7 | 17 | 23 | |
| 17 | 1 | Wimbledon | 33 | 7 | 11 | 15 | 43 | 63 | -20 | 32 | LLLL | 17 | 6 | 6 | 5 | 27 | 24 | 16 | 1 | 5 | 10 | 16 | 39 | |
| 18 | Bradford City | 32 | 6 | 8 | 18 | 29 | 57 | -28 | 26 | LLLL | 16 | 4 | 7 | 5 | 18 | 25 | 16 | 2 | 1 | 13 | 11 | 32 | ||
| 19 | Sheffield Wednesday | 32 | 6 | 6 | 20 | 29 | 58 | -29 | 24 | WLLL | 15 | 4 | 3 | 8 | 16 | 18 | 17 | 2 | 3 | 12 | 13 | 40 | ||
| 20 | Watford | 32 | 5 | 5 | 22 | 28 | 65 | -37 | 20 | OLXW | 16 | 4 | 4 | 8 | 19 | 25 | 16 | 1 | 1 | 14 | 9 | 40 | ||
| 27 | Kevin PHILLIPS (Sunderland, 6p) | |
| 19 | +1 | Andrew COLE (Manchester United) |
| Alan SHEARER (Newcastle United, 4p) | ||
| 17 | Dwight YORKE (Manchester United) | |
| 15 | Michael BRIDGES (Leeds United) | |
| 13 | +1 | Niall QUINN (Sunderland) |
| Steffen IVERSEN (Tottenham Hotspur) | ||
| Paolo DI CANIO (West Ham United, 2p) | ||
| 12 | Kevin CAMPBELL (Everton) | |
| 11 | Hamilton RICARD (Middlesbrough, 3p) | |
| +1 | Michael OWEN (Liverpool, 1p) | |
| Robbie KEANE (Coventry City) | ||
| Chris ARMSTRONG (Tottenham Hotspur) | ||
| Thierry HENRY (Arsenal, 2p) | ||
| 10 | +1 | Marians PAHARS (Southampton) |
| +2 | Paulo WANCHOPE (West Ham United) | |
| Nwankwo KANU (Arsenal, 1p) | ||
| 9 | Dion DUBLIN (Aston Villa) | |
| +1 | Gary McALLISTER (Coventry City, 4p) | |
| Harry KEWELL (Leeds United) | ||
| +1 | Paul SCHOLES (Manchester United, 1p) | |
| Titi CAMARA (Liverpool) | ||
| John HARTSON (Wimbledon) | ||
| Carl CORT (Wimbledon) | ||
| +1 | Patrik BERGER (Liverpool, 1p) | |
| Tony COTTEE (Leicester City) | ||
| Tore André FLO (Chelsea) |
| Saturday, 8 April 2000 | |||||
| 32 | Bradford City | 1-2 | Southampton | ||
| 77 | Blake | 56 | Marsden | ||
| 76 | Pahars | ||||
| 32 | Leicester City | 1-1 | Everton | ||
| 8 | Taggart | 27 | Hutchison | ||
| 32 | Sunderland | 2-1 | Wimbledon | ||
| 56 | Quinn | 74 | Hughes | ||
| 81 | Kilbane | ||||
| 32 | Watford | 0-0 | Derby County | ||
| Sunday, 9 April 2000 | |||||
| 32 | Aston Villa | 1-0 | Leeds United | ||
| 40 | Joachim | ||||
| 32 | Liverpool | 2-0 | Tottenham Hotspur | ||
| 34 | Berger | ||||
| 61 | Owen | ||||
| Monday, 10 April 2000 | |||||
| 32 | Middlesbrough | 3-4 | Manchester United | ||
| 18 | Campbell | 46 | Giggs | ||
| 86 | Ince | 60 | Cole | ||
| 90 | Juninho Paulista | 74 | Scholes | ||
| 88 | Fortune | ||||
| Wednesday, 12 April 2000 | |||||
| 32 | Chelsea | 2-1 | Coventry City | ||
| 52(og) | Hendry | 17 | McAllister | ||
| 57 | Zola | ||||
| 32 | West Ham United | 2-1 | Newcastle United | ||
| 60 | Wanchope | 47 | Speed | ||
| 89 | Wanchope | ||||
| 35 | Wimbledon | 0-2 | Sheffield Wednesday | ||
| 39 | De Bilde | ||||
| 87 | Sibon | ||||