Major League| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 |
| 18 | 19 | 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 280 | 746 | 2.66 | 150 | 53.57% | 61 | 21.79% | 69 | 24.64% |
| Eastern | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Sporting Kansas City | 30 | 16 | 7 | 7 | 37 | 25 | +12 | 55 | OWXW | 15 | 8 | 4 | 3 | 18 | 11 | 15 | 8 | 3 | 4 | 19 | 14 | ||
| 2 | Chicago Fire | 29 | 16 | 5 | 8 | 42 | 34 | +8 | 53 | WWWW | 15 | 11 | 2 | 2 | 25 | 14 | 14 | 5 | 3 | 6 | 17 | 20 | ||
| 3 | New York Red Bulls | 30 | 14 | 8 | 8 | 50 | 43 | +7 | 50 | XLWX | 14 | 10 | 3 | 1 | 30 | 15 | 16 | 4 | 5 | 7 | 20 | 28 | ||
| 4 | 1 | D.C. United | 29 | 14 | 5 | 10 | 46 | 39 | +7 | 47 | WWLX | 15 | 10 | 4 | 1 | 33 | 15 | 14 | 4 | 1 | 9 | 13 | 24 | |
| 5 | 1 | Houston Dynamo | 29 | 12 | 10 | 7 | 41 | 34 | +7 | 46 | XWLX | 14 | 9 | 5 | 0 | 25 | 10 | 15 | 3 | 5 | 7 | 16 | 24 | |
| 6 | Columbus Crew | 30 | 13 | 6 | 11 | 36 | 37 | -1 | 45 | LWLL | 14 | 9 | 2 | 3 | 22 | 17 | 16 | 4 | 4 | 8 | 14 | 20 | ||
| 7 | Montréal Impact | 31 | 12 | 4 | 15 | 44 | 49 | -5 | 40 | OLLW | 16 | 10 | 3 | 3 | 31 | 18 | 15 | 2 | 1 | 12 | 13 | 31 | ||
| 8 | New England Revolution | 30 | 7 | 8 | 15 | 37 | 41 | -4 | 29 | XLWO | 16 | 6 | 6 | 4 | 22 | 15 | 14 | 1 | 2 | 11 | 15 | 26 | ||
| 9 | Philadelphia Union | 27 | 7 | 6 | 14 | 26 | 32 | -6 | 27 | LXOL | 14 | 5 | 2 | 7 | 18 | 16 | 13 | 2 | 4 | 7 | 8 | 16 | ||
| 10 | Toronto FC | 30 | 5 | 7 | 18 | 34 | 55 | -21 | 22 | LXLL | 15 | 3 | 4 | 8 | 15 | 24 | 15 | 2 | 3 | 10 | 19 | 31 | ||
| Western | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | San Jose Earthquakes | 30 | 18 | 6 | 6 | 62 | 36 | +26 | 60 | WXWW | 15 | 10 | 4 | 1 | 38 | 17 | 15 | 8 | 2 | 5 | 24 | 19 | ||
| 2 | 1 | LA Galaxy | 30 | 15 | 4 | 11 | 54 | 42 | +12 | 49 | WWWW | 15 | 9 | 1 | 5 | 29 | 18 | 15 | 6 | 3 | 6 | 25 | 24 | |
| 3 | 1 | Real Salt Lake | 30 | 15 | 4 | 11 | 40 | 34 | +6 | 49 | WLWO | 16 | 11 | 1 | 4 | 27 | 15 | 14 | 4 | 3 | 7 | 13 | 19 | |
| 4 | 2 | Seattle Sounders | 29 | 13 | 9 | 7 | 45 | 31 | +14 | 48 | LXWX | 14 | 9 | 1 | 4 | 21 | 10 | 15 | 4 | 8 | 3 | 24 | 21 | |
| 5 | Vancouver Whitecaps | 29 | 10 | 7 | 12 | 29 | 38 | -9 | 37 | LLLL | 13 | 7 | 4 | 2 | 19 | 14 | 16 | 3 | 3 | 10 | 10 | 24 | ||
| 6 | FC Dallas | 30 | 9 | 9 | 12 | 35 | 38 | -3 | 36 | WXLW | 16 | 6 | 7 | 3 | 19 | 14 | 14 | 3 | 2 | 9 | 16 | 24 | ||
| 7 | Colorado Rapids | 29 | 9 | 2 | 18 | 36 | 43 | -7 | 29 | LWLL | 14 | 7 | 2 | 5 | 25 | 14 | 15 | 2 | 0 | 13 | 11 | 29 | ||
| 8 | Portland Timbers | 30 | 7 | 8 | 15 | 31 | 51 | -20 | 29 | LXXL | 15 | 7 | 4 | 4 | 22 | 19 | 15 | 0 | 4 | 11 | 9 | 32 | ||
| 9 | Chivas USA | 28 | 7 | 7 | 14 | 21 | 44 | -23 | 28 | LLLL | 14 | 3 | 2 | 9 | 8 | 23 | 14 | 4 | 5 | 5 | 13 | 21 | ||
| 22 | +3 | Chris WONDOLOWSKI (San Jose Earthquakes) |
| 14 | Kenny COOPER (New York Red Bulls) | |
| Álvaro SABORIO (Real Salt Lake) | ||
| +2 | Robbie KEANE (LA Galaxy) | |
| 13 | Eddie JOHNSON (Seattle Sounders) | |
| Thierry HENRY (New York Red Bulls) | ||
| 12 | Fredy MONTERO (Seattle Sounders) | |
| Alan GORDON (San Jose Earthquakes) | ||
| 11 | +1 | Kei KAMARA (Sporting Kansas City) |
| Chris PONTIUS (D.C. United) | ||
| Will BRUIN (Houston Dynamo) | ||
| Saër SÈNE (New England Revolution) | ||
| 9 | Landon DONOVAN (LA Galaxy) | |
| Danny KOEVERMANS (Toronto FC) | ||
| Patrice BERNIER (Montréal Impact) | ||
| 8 | +1 | Simon DAWKINS (San Jose Earthquakes) |
| +2 | Chris ROLFE (Chicago Fire) | |
| Steven LENHART (San Jose Earthquakes) | ||
| 7 | Brad DAVIS (Houston Dynamo) | |
| +1 | Lionard PAJOY (D.C. United) | |
| Eddie GAVEN (Columbus Crew) | ||
| Jaime CASTRILLÓN (Colorado Rapids) | ||
| +1 | Edgar ESPÍNDOLA (Real Salt Lake) | |
| Dwayne DE ROSARIO (D.C. United) | ||
| Darren MATTOCKS (Vancouver Whitecaps) | ||
| +2 | JUNINHO (LA Galaxy) | |
| Kris BOYD (Portland Timbers) | ||
| +1 | C.J. SAPONG (Sporting Kansas City) | |
| David BECKHAM (LA Galaxy) | ||
| MAICON CARIOCA (D.C. United) |
| Wednesday, 19 September 2012 | |||||
| Columbus Crew | 1-0 | Chivas USA | |||
| 89 | Meram | ||||
| New York Red Bulls | 0-2 | Sporting Kansas City | |||
| 12 | Sapong | ||||
| 19 | Kamara | ||||
| San Jose Earthquakes | 2-2 | Portland Timbers | |||
| 73 | Wondolowski | 45 | Mwanga | ||
| 90 | Wondolowski | 62 | Mwanga | ||
| Thursday, 20 September 2012 | |||||
| Philadelphia Union | 0-1 | D.C. United | |||
| 67 | Pajoy | ||||
| Saturday, 22 September 2012 | |||||
| Real Salt Lake | 2-1 | Portland Timbers | |||
| 14 | Espíndola | 61 | Dike | ||
| 36 | Morales | ||||
| New England Revolution | 1-1 | New York Red Bulls | |||
| 90 | Barnes | 90 | Lindpere | ||
| Chicago Fire | 2-1 | Columbus Crew | |||
| 23 | Rolfe | 15 | Arrieta | ||
| 26 | Rolfe | ||||
| Montréal Impact | 0-0 | Sporting Kansas City | |||
| LA Galaxy | 4-2 | Toronto FC | |||
| 11 | Juninho | 38 | Dunfield | ||
| 33 | Juninho | 86 | Silva | ||
| 36 | Keane | ||||
| 90 | Keane | ||||
| Seattle Sounders | 1-2 | San Jose Earthquakes | |||
| 14 | Zakuani | 2 | Dawkins | ||
| 30 | Wondolowski | ||||
