| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 |
| 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 370 | 960 | 2.59 | 179 | 48.38% | 98 | 26.49% | 93 | 25.14% |
| 2000/01 | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Manchester United | 37 | 24 | 8 | 5 | 78 | 28 | +50 | 80 | LLWX | 19 | 15 | 2 | 2 | 49 | 12 | 18 | 9 | 6 | 3 | 29 | 16 | ||
| 2 | Arsenal | 37 | 20 | 10 | 7 | 61 | 35 | +26 | 70 | OWWW | 19 | 15 | 3 | 1 | 45 | 13 | 18 | 5 | 7 | 6 | 16 | 22 | ||
| 3 | Liverpool | 37 | 19 | 9 | 9 | 67 | 39 | +28 | 66 | XWWW | 19 | 13 | 4 | 2 | 40 | 14 | 18 | 6 | 5 | 7 | 27 | 25 | ||
| 4 | Leeds United | 37 | 19 | 8 | 10 | 61 | 42 | +19 | 65 | WLWW | 18 | 10 | 3 | 5 | 33 | 20 | 19 | 9 | 5 | 5 | 28 | 22 | ||
| 5 | Ipswich Town | 37 | 20 | 5 | 12 | 56 | 41 | +15 | 65 | WLWW | 19 | 11 | 5 | 3 | 31 | 15 | 18 | 9 | 0 | 9 | 25 | 26 | ||
| 6 | Chelsea | 37 | 16 | 10 | 11 | 66 | 44 | +22 | 58 | XWLL | 19 | 13 | 3 | 3 | 44 | 20 | 18 | 3 | 7 | 8 | 22 | 24 | ||
| 7 | Sunderland | 37 | 15 | 11 | 11 | 44 | 39 | +5 | 56 | WWXL | 19 | 9 | 7 | 3 | 24 | 16 | 18 | 6 | 4 | 8 | 20 | 23 | ||
| 8 | 1 | Aston Villa | 37 | 13 | 15 | 9 | 46 | 40 | +6 | 54 | WOOX | 19 | 8 | 8 | 3 | 27 | 20 | 18 | 5 | 7 | 6 | 19 | 20 | |
| 9 | 1 | Charlton Athletic | 37 | 14 | 10 | 13 | 50 | 53 | -3 | 52 | LWWX | 18 | 11 | 5 | 2 | 31 | 15 | 19 | 3 | 5 | 11 | 19 | 38 | |
| 10 | 2 | Southampton | 37 | 13 | 10 | 14 | 37 | 46 | -9 | 49 | WLXL | 18 | 10 | 2 | 6 | 24 | 20 | 19 | 3 | 8 | 8 | 13 | 26 | |
| 11 | 1 | Newcastle United | 37 | 13 | 9 | 15 | 41 | 50 | -9 | 48 | OLXW | 18 | 9 | 4 | 5 | 23 | 17 | 19 | 4 | 5 | 10 | 18 | 33 | |
| 12 | 1 | Leicester City | 37 | 14 | 6 | 17 | 38 | 48 | -10 | 48 | WLLL | 19 | 10 | 4 | 5 | 28 | 23 | 18 | 4 | 2 | 12 | 10 | 25 | |
| 13 | 2 | Tottenham Hotspur | 37 | 12 | 10 | 15 | 44 | 53 | -9 | 46 | LOLL | 18 | 10 | 6 | 2 | 28 | 15 | 19 | 2 | 4 | 13 | 16 | 38 | |
| 14 | 1 | West Ham United | 37 | 10 | 12 | 15 | 44 | 48 | -4 | 42 | WLLL | 19 | 6 | 6 | 7 | 24 | 20 | 18 | 4 | 6 | 8 | 20 | 28 | |
| 15 | 1 | Everton | 37 | 11 | 8 | 18 | 43 | 57 | -14 | 41 | LWLL | 18 | 6 | 7 | 5 | 27 | 25 | 19 | 5 | 1 | 13 | 16 | 32 | |
| 16 | 1 | Derby County | 37 | 10 | 11 | 16 | 36 | 58 | -22 | 41 | WLLW | 18 | 8 | 6 | 4 | 22 | 23 | 19 | 2 | 5 | 12 | 14 | 35 | |
| 17 | 1 | Middlesbrough | 37 | 8 | 15 | 14 | 42 | 43 | -1 | 39 | XLWL | 18 | 3 | 7 | 8 | 16 | 22 | 19 | 5 | 8 | 6 | 26 | 21 | |
| 18 | Manchester City | 37 | 8 | 10 | 19 | 40 | 63 | -23 | 34 | LWXW | 18 | 4 | 3 | 11 | 19 | 29 | 19 | 4 | 7 | 8 | 21 | 34 | ||
| 19 | Coventry City | 37 | 8 | 9 | 20 | 36 | 63 | -27 | 33 | LLLW | 18 | 4 | 6 | 8 | 14 | 23 | 19 | 4 | 3 | 12 | 22 | 40 | ||
| 20 | Bradford City | 37 | 5 | 10 | 22 | 30 | 70 | -40 | 25 | LXLL | 19 | 4 | 7 | 8 | 20 | 29 | 18 | 1 | 3 | 14 | 10 | 41 | ||
| 22 | +4 | Jimmy HASSELBAINK (Chelsea, 3p) |
| 19 | Marcus STEWART (Ipswich Town, 2p) | |
| 17 | +1 | Mark VIDUKA (Leeds United) |
| Thierry HENRY (Arsenal, 1p) | ||
| 15 | Teddy SHERINGHAM (Manchester United, 1p) | |
| +5 | Michael OWEN (Liverpool) | |
| 14 | Emile HESKEY (Liverpool) | |
| 12 | Alen BOKSIC (Middlesbrough, 2p) | |
| +1 | Kevin PHILLIPS (Sunderland, 2p) | |
| 11 | James BEATTIE (Southampton) | |
| Ole SOLSKJÆR (Manchester United) | ||
| Gustavo POYET (Chelsea) | ||
| Jonatan JOHANSSON (Charlton Athletic) | ||
| +1 | Frédéric KANOUTÉ (West Ham United) | |
| 10 | Andrew COLE (Manchester United) | |
| Eiður GUÐJOHNSEN (Chelsea) | ||
| +1 | Paolo DI CANIO (West Ham United, 3p) | |
| 9 | +1 | Kevin CAMPBELL (Everton) |
| Ade AKINBIYI (Leicester City) | ||
| +1 | Alan SMITH (Leeds United) | |
| +1 | Lee BOWYER (Leeds United) | |
| Robbie KEANE (Leeds United, 1p) | ||
| Gianfranco ZOLA (Chelsea) | ||
| +1 | Marians PAHARS (Southampton) | |
| Paulo WANCHOPE (Manchester City) | ||
| David BECKHAM (Manchester United, 1p) | ||
| Les FERDINAND (Tottenham Hotspur) | ||
| Serhiy REBROV (Tottenham Hotspur, 1p) |
| Saturday, 5 May 2001 | |||||
| 37 | Arsenal | 2-1 | Leeds United | ||
| 17 | Ljungberg | 58 | Harte | ||
| 56 | Wiltord | ||||
| 37 | Aston Villa | 3-2 | Coventry City | ||
| 61 | Vassell | 18 | Hadji | ||
| 81 | Ángel | 26 | Hadji | ||
| 86 | Merson | ||||
| 37 | Bradford City | 1-1 | Middlesbrough | ||
| 38 | Jacobs | 81 | Karembeu | ||
| 37 | Chelsea | 2-1 | Everton | ||
| 32 | Hasselbaink | 3 | Campbell | ||
| 35 | Hasselbaink | ||||
| 37 | Leicester City | 4-2 | Tottenham Hotspur | ||
| 42 | Rowett | 54 | Davies | ||
| 56 | Sturridge | 61 | Carr | ||
| 82 | Guppy | ||||
| 90 | Savage | ||||
| 37 | Liverpool | 3-0 | Newcastle United | ||
| 25 | Owen | ||||
| 72 | Owen | ||||
| 81 | Owen | ||||
| 37 | Manchester United | 0-1 | Derby County | ||
| 34 | Christie | ||||
| 37 | Sunderland | 3-2 | Charlton Athletic | ||
| 11 | Kilbane | 18 | Svensson | ||
| 20 | Quinn | 60 | Jensen | ||
| 50 | Phillips | ||||
| 37 | West Ham United | 3-0 | Southampton | ||
| 59 | Cole | ||||
| 70 | Di Canio | ||||
| 90 | Kanouté | ||||
| Monday, 7 May 2001 | |||||
| 37 | Ipswich Town | 2-1 | Manchester City | ||
| 78 | Holland | 74 | Goater | ||
| 85 | Reuser | ||||
| Tuesday, 8 May 2001 | |||||
| 28 | Liverpool | 2-2 | Chelsea | ||
| 8 | Owen | 13 | Hasselbaink | ||
| 60 | Owen | 66 | Hasselbaink | ||
| Sunday, 13 May 2001 | |||||
| 34 | Leeds United | 6-1 | Bradford City | ||
| 14 | Viduka | 22 | Ward | ||
| 19 | Harte | ||||
| 27 | Bakke | ||||
| 38 | Smith | ||||
| 43 | Kewell | ||||
| 84 | Bowyer | ||||
| 34 | Southampton | 2-1 | Manchester United | ||
| 11(og) | Brown | 71 | Giggs | ||
| 15 | Pahars | ||||
| Tuesday, 15 May 2001 | |||||
| 32 | Newcastle United | 0-0 | Arsenal | ||