| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 |
| 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 296 | 754 | 2.54 | 141 | 47.64% | 85 | 28.72% | 70 | 23.65% |
| 2000/01 | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Manchester United | 30 | 21 | 7 | 2 | 68 | 19 | +49 | 70 | WXWX | 15 | 13 | 1 | 1 | 42 | 7 | 15 | 8 | 6 | 1 | 26 | 12 | ||
| 2 | Arsenal | 30 | 15 | 9 | 6 | 47 | 29 | +18 | 54 | OWLW | 15 | 12 | 3 | 0 | 37 | 8 | 15 | 3 | 6 | 6 | 10 | 21 | ||
| 3 | Ipswich Town | 30 | 15 | 4 | 11 | 44 | 36 | +8 | 49 | WLWW | 15 | 8 | 4 | 3 | 25 | 13 | 15 | 7 | 0 | 8 | 19 | 23 | ||
| 4 | 1 | Sunderland | 30 | 13 | 9 | 8 | 37 | 30 | +7 | 48 | WXLX | 15 | 8 | 6 | 1 | 18 | 8 | 15 | 5 | 3 | 7 | 19 | 22 | |
| 5 | 2 | Leeds United | 30 | 13 | 8 | 9 | 44 | 38 | +6 | 47 | WXWO | 15 | 7 | 3 | 5 | 23 | 19 | 15 | 6 | 5 | 4 | 21 | 19 | |
| 6 | 2 | Liverpool | 28 | 13 | 7 | 8 | 48 | 31 | +17 | 46 | XLXW | 14 | 10 | 3 | 1 | 29 | 9 | 14 | 3 | 4 | 7 | 19 | 22 | |
| 7 | 1 | Leicester City | 29 | 13 | 6 | 10 | 31 | 31 | +0 | 45 | LWWL | 15 | 9 | 4 | 2 | 22 | 13 | 14 | 4 | 2 | 8 | 9 | 18 | |
| 8 | 2 | Southampton | 29 | 12 | 8 | 9 | 34 | 34 | +0 | 44 | WWWW | 15 | 9 | 2 | 4 | 22 | 15 | 14 | 3 | 6 | 5 | 12 | 19 | |
| 9 | 1 | Chelsea | 29 | 11 | 9 | 9 | 52 | 37 | +15 | 42 | LWOX | 15 | 10 | 3 | 2 | 39 | 17 | 14 | 1 | 6 | 7 | 13 | 20 | |
| 10 | 1 | Charlton Athletic | 30 | 11 | 9 | 10 | 39 | 42 | -3 | 42 | LOXW | 15 | 9 | 4 | 2 | 24 | 11 | 15 | 2 | 5 | 8 | 15 | 31 | |
| 11 | 2 | Tottenham Hotspur | 30 | 10 | 9 | 11 | 36 | 38 | -2 | 39 | WLLW | 15 | 9 | 5 | 1 | 26 | 11 | 15 | 1 | 4 | 10 | 10 | 27 | |
| 12 | Aston Villa | 29 | 9 | 11 | 9 | 31 | 30 | +1 | 38 | OWXL | 14 | 5 | 6 | 3 | 18 | 14 | 15 | 4 | 5 | 6 | 13 | 16 | ||
| 13 | 2 | Newcastle United | 29 | 11 | 5 | 13 | 34 | 41 | -7 | 38 | LXLL | 14 | 7 | 2 | 5 | 19 | 15 | 15 | 4 | 3 | 8 | 15 | 26 | |
| 14 | West Ham United | 30 | 8 | 11 | 11 | 35 | 38 | -3 | 35 | LLLW | 15 | 4 | 6 | 5 | 18 | 15 | 15 | 4 | 5 | 6 | 17 | 23 | ||
| 15 | Derby County | 30 | 8 | 11 | 11 | 31 | 45 | -14 | 35 | XWWO | 15 | 7 | 6 | 2 | 19 | 17 | 15 | 1 | 5 | 9 | 12 | 28 | ||
| 16 | Everton | 30 | 8 | 8 | 14 | 31 | 44 | -13 | 32 | LXLW | 15 | 4 | 7 | 4 | 20 | 20 | 15 | 4 | 1 | 10 | 11 | 24 | ||
| 17 | Middlesbrough | 30 | 6 | 13 | 11 | 33 | 36 | -3 | 31 | WOLX | 15 | 3 | 6 | 6 | 15 | 18 | 15 | 3 | 7 | 5 | 18 | 18 | ||
| 18 | Manchester City | 30 | 6 | 9 | 15 | 33 | 49 | -16 | 27 | XLWL | 15 | 3 | 3 | 9 | 17 | 22 | 15 | 3 | 6 | 6 | 16 | 27 | ||
| 19 | Coventry City | 30 | 5 | 9 | 16 | 26 | 51 | -25 | 24 | LOXX | 15 | 2 | 6 | 7 | 11 | 21 | 15 | 3 | 3 | 9 | 15 | 30 | ||
| 20 | Bradford City | 29 | 3 | 8 | 18 | 20 | 55 | -35 | 17 | XLLL | 14 | 2 | 5 | 7 | 13 | 24 | 15 | 1 | 3 | 11 | 7 | 31 | ||
| 16 | Jimmy HASSELBAINK (Chelsea, 3p) | |
| 15 | Marcus STEWART (Ipswich Town) | |
| Thierry HENRY (Arsenal, 1p) | ||
| 14 | Teddy SHERINGHAM (Manchester United) | |
| +1 | Mark VIDUKA (Leeds United) | |
| 11 | James BEATTIE (Southampton) | |
| +2 | Alen BOKSIC (Middlesbrough, 2p) | |
| Emile HESKEY (Liverpool) | ||
| Jonatan JOHANSSON (Charlton Athletic) | ||
| +1 | Kevin PHILLIPS (Sunderland, 2p) | |
| 10 | +1 | Ole SOLSKJÆR (Manchester United) |
| 9 | +1 | Michael OWEN (Liverpool) |
| Andrew COLE (Manchester United) | ||
| Paolo DI CANIO (West Ham United, 3p) | ||
| +1 | Les FERDINAND (Tottenham Hotspur) | |
| +1 | Serhiy REBROV (Tottenham Hotspur, 1p) | |
| 8 | +1 | Eiður GUÐJOHNSEN (Chelsea) |
| Paulo WANCHOPE (Manchester City) | ||
| David BECKHAM (Manchester United, 1p) | ||
| +2 | Don HUTCHISON (Sunderland) | |
| Frédéric KANOUTÉ (West Ham United) |
| Saturday, 17 March 2001 | |||||
| 30 | Bradford City | 2-2 | Manchester City | ||
| 52 | Blake | 22 | Wiekens | ||
| 57 | Ward | 70 | Goater | ||
| 30 | Charlton Athletic | 1-2 | Leeds United | ||
| 18 | Bartlett | 1 | Viduka | ||
| 46 | Smith | ||||
| 30 | Chelsea | 2-4 | Sunderland | ||
| 15 | Desailly | 28 | Hutchison | ||
| 38 | Guðjohnsen | 52 | Hutchison | ||
| 61 | McCann | ||||
| 79 | Phillips | ||||
| 30 | Manchester United | 2-0 | Leicester City | ||
| 88 | Solskjær | ||||
| 90 | Silvestre | ||||
| 30 | Newcastle United | 1-2 | Middlesbrough | ||
| 60 | Cort | 28 | Boksic | ||
| 33 | Boksic | ||||
| 30 | Southampton | 1-0 | Everton | ||
| 58 | Tessem | ||||
| 30 | Tottenham Hotspur | 3-0 | Coventry City | ||
| 29 | Iversen | ||||
| 34 | Ferdinand | ||||
| 59 | Rebrov | ||||
| 30 | West Ham United | 0-1 | Ipswich Town | ||
| 60 | Reuser | ||||
| Sunday, 18 March 2001 | |||||
| 30 | Aston Villa | 0-0 | Arsenal | ||
| 30 | Liverpool | 1-1 | Derby County | ||
| 52 | Owen | 9 | Burton | ||