| ROUND | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 |
| 20 | 21 | 22 | 23 | 24 | 25 | 26 | 27 | 28 | 29 | 30 | 31 | 32 | 33 | 34 | 35 | 36 | 37 | 38 |
| Season archive |
| Games | Goals | H | D | A | ||||
| 169 | 458 | 2.71 | 84 | 49.70% | 44 | 26.04% | 41 | 24.26% |
| 2000/01 | Overall | Home | Away | |||||||||||||||||||||
| P | W | D | L | F | A | Gdf | Pts | Form | P | W | D | L | F | A | P | W | D | L | F | A | ||||
| 1 | Manchester United | 17 | 12 | 4 | 1 | 44 | 13 | +31 | 40 | XWWW | 8 | 7 | 1 | 0 | 26 | 4 | 9 | 5 | 3 | 1 | 18 | 9 | ||
| 2 | Arsenal | 17 | 10 | 4 | 3 | 29 | 13 | +16 | 34 | WWLL | 9 | 8 | 1 | 0 | 22 | 4 | 8 | 2 | 3 | 3 | 7 | 9 | ||
| 3 | 2 | Ipswich Town | 17 | 9 | 3 | 5 | 24 | 17 | +7 | 30 | WLWW | 8 | 3 | 3 | 2 | 9 | 7 | 9 | 6 | 0 | 3 | 15 | 10 | |
| 4 | 1 | Leicester City | 17 | 8 | 5 | 4 | 17 | 13 | +4 | 29 | LWLW | 8 | 4 | 3 | 1 | 10 | 8 | 9 | 4 | 2 | 3 | 7 | 5 | |
| 5 | 1 | Sunderland | 17 | 8 | 5 | 4 | 18 | 16 | +2 | 29 | WWWW | 9 | 6 | 3 | 0 | 11 | 4 | 8 | 2 | 2 | 4 | 7 | 12 | |
| 6 | 2 | Liverpool | 17 | 8 | 3 | 6 | 32 | 24 | +8 | 27 | LWLL | 9 | 7 | 1 | 1 | 19 | 7 | 8 | 1 | 2 | 5 | 13 | 17 | |
| 7 | West Ham United | 17 | 6 | 7 | 4 | 23 | 18 | +5 | 25 | XWWW | 9 | 3 | 4 | 2 | 12 | 9 | 8 | 3 | 3 | 2 | 11 | 9 | ||
| 8 | Aston Villa | 16 | 6 | 7 | 3 | 19 | 14 | +5 | 25 | XXXL | 7 | 4 | 3 | 0 | 12 | 4 | 9 | 2 | 4 | 3 | 7 | 10 | ||
| 9 | 1 | Tottenham Hotspur | 17 | 7 | 3 | 7 | 25 | 26 | -1 | 24 | XLWW | 8 | 7 | 1 | 0 | 17 | 6 | 9 | 0 | 2 | 7 | 8 | 20 | |
| 10 | 1 | Newcastle United | 17 | 7 | 3 | 7 | 18 | 21 | -3 | 24 | LXWL | 8 | 4 | 1 | 3 | 10 | 8 | 9 | 3 | 2 | 4 | 8 | 13 | |
| 11 | 3 | Chelsea | 17 | 6 | 5 | 6 | 32 | 24 | +8 | 23 | WWLL | 9 | 6 | 2 | 1 | 25 | 10 | 8 | 0 | 3 | 5 | 7 | 14 | |
| 12 | 1 | Leeds United | 16 | 6 | 4 | 6 | 22 | 23 | -1 | 22 | LLWL | 8 | 5 | 0 | 3 | 16 | 12 | 8 | 1 | 4 | 3 | 6 | 11 | |
| 13 | 1 | Charlton Athletic | 17 | 6 | 4 | 7 | 24 | 27 | -3 | 22 | XLLW | 9 | 5 | 3 | 1 | 16 | 7 | 8 | 1 | 1 | 6 | 8 | 20 | |
| 14 | 1 | Everton | 17 | 6 | 3 | 8 | 19 | 28 | -9 | 21 | LLWW | 8 | 3 | 2 | 3 | 11 | 11 | 9 | 3 | 1 | 5 | 8 | 17 | |
| 15 | Southampton | 17 | 5 | 5 | 7 | 22 | 28 | -6 | 20 | WLLW | 9 | 4 | 1 | 4 | 15 | 15 | 8 | 1 | 4 | 3 | 7 | 13 | ||
| 16 | Manchester City | 17 | 5 | 2 | 10 | 23 | 30 | -7 | 17 | WLLL | 9 | 3 | 1 | 5 | 15 | 11 | 8 | 2 | 1 | 5 | 8 | 19 | ||
| 17 | 1 | Coventry City | 17 | 4 | 3 | 10 | 16 | 32 | -16 | 15 | WLXL | 9 | 2 | 2 | 5 | 6 | 13 | 8 | 2 | 1 | 5 | 10 | 19 | |
| 18 | 1 | Derby County | 17 | 2 | 7 | 8 | 20 | 35 | -15 | 13 | LWLW | 8 | 1 | 5 | 2 | 10 | 15 | 9 | 1 | 2 | 6 | 10 | 20 | |
| 19 | 1 | Bradford City | 17 | 2 | 6 | 9 | 12 | 28 | -16 | 12 | XWXL | 9 | 2 | 4 | 3 | 9 | 10 | 8 | 0 | 2 | 6 | 3 | 18 | |
| 20 | 1 | Middlesbrough | 17 | 2 | 5 | 10 | 19 | 28 | -9 | 11 | LLXL | 8 | 0 | 3 | 5 | 7 | 15 | 9 | 2 | 2 | 5 | 12 | 13 | |
| 11 | Teddy SHERINGHAM (Manchester United) | |
| Mark VIDUKA (Leeds United) | ||
| Jimmy HASSELBAINK (Chelsea, 3p) | ||
| 10 | Emile HESKEY (Liverpool) | |
| +1 | Marcus STEWART (Ipswich Town) | |
| +1 | Thierry HENRY (Arsenal, 1p) | |
| 7 | +1 | James BEATTIE (Southampton) |
| Michael OWEN (Liverpool) | ||
| David BECKHAM (Manchester United) | ||
| Paolo DI CANIO (West Ham United, 3p) | ||
| 6 | Alan SMITH (Leeds United) | |
| +1 | Gianfranco ZOLA (Chelsea) | |
| Andrew COLE (Manchester United) | ||
| Marians PAHARS (Southampton) | ||
| +1 | Paulo WANCHOPE (Manchester City) | |
| Jonatan JOHANSSON (Charlton Athletic) | ||
| Les FERDINAND (Tottenham Hotspur) | ||
| 5 | Malcolm CHRISTIE (Derby County) | |
| Alen BOKSIC (Middlesbrough, 1p) | ||
| Alan SHEARER (Newcastle United, 2p) | ||
| Kevin PHILLIPS (Sunderland, 1p) | ||
| Serhiy REBROV (Tottenham Hotspur, 1p) | ||
| Francis JEFFERS (Everton) |
| Saturday, 9 December 2000 | |||||
| 17 | Arsenal | 5-0 | Newcastle United | ||
| 13 | Henry | ||||
| 16 | Parlour | ||||
| 52 | Kanu | ||||
| 86 | Parlour | ||||
| 90 | Parlour | ||||
| 17 | Bradford City | 3-3 | Tottenham Hotspur | ||
| 9 | Lawrence | 1 | King | ||
| 69 | Windass | 21 | Campbell | ||
| 89 | Carbone | 54 | Armstrong | ||
| 17 | Charlton Athletic | 3-3 | Manchester United | ||
| 10 | Bartlett | 42 | Giggs | ||
| 79 | Bartlett | 43 | Solskjær | ||
| 85 | Robinson | 66 | Keane | ||
| 17 | Chelsea | 4-1 | Derby County | ||
| 10 | Guðjohnsen | 56 | Riggott | ||
| 16 | Guðjohnsen | ||||
| 37 | Poyet | ||||
| 54 | Zola | ||||
| 17 | Manchester City | 5-0 | Everton | ||
| 14 | Wanchope | ||||
| 23 | Howey | ||||
| 42 | Goater | ||||
| 54 | Dickov | ||||
| 67(og) | Naysmith | ||||
| 17 | Southampton | 1-0 | Leeds United | ||
| 43 | Beattie | ||||
| 17 | Sunderland | 1-0 | Middlesbrough | ||
| 54 | Gray | ||||
| 17 | West Ham United | 1-1 | Aston Villa | ||
| 15 | Carrick | 37 | Hendrie | ||
| Sunday, 10 December 2000 | |||||
| 17 | Coventry City | 1-0 | Leicester City | ||
| 40 | Bellamy | ||||
| 17 | Liverpool | 0-1 | Ipswich Town | ||
| 45 | Stewart | ||||